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6B5B
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BU of 6b5b by Molmil
Cryo-EM structure of the NAIP5-NLRC4-flagellin inflammasome
Descriptor: Baculoviral IAP repeat-containing protein 1e, Flagellin, NLR family CARD domain-containing protein 4
Authors:Tenthorey, J.L, Haloupek, N, Lopez-Blanco, J.R, Grob, P, Adamson, E, Hartenian, E, Lind, N.A, Bourgeois, N.M, Chacon, P, Nogales, E, Vance, R.E.
Deposit date:2017-09-29
Release date:2017-11-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.
Science, 358, 2017
3J47
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BU of 3j47 by Molmil
Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid
Descriptor: 26S proteasome regulatory subunit RPN11, 26S proteasome regulatory subunit RPN12, 26S proteasome regulatory subunit RPN3, ...
Authors:Estrin, E, Lopez-Blanco, J.R, Chacon, P, Martin, A.
Deposit date:2013-06-27
Release date:2013-08-28
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Formation of an Intricate Helical Bundle Dictates the Assembly of the 26S Proteasome Lid.
Structure, 21, 2013
5KMG
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BU of 5kmg by Molmil
Near-atomic cryo-EM structure of PRC1 bound to the microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kellogg, E.H, Howes, S, Ti, S.-C, Ramirez-Aportela, E, Kapoor, T.M, Chacon, P, Nogales, E.
Deposit date:2016-06-27
Release date:2016-08-03
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Near-atomic cryo-EM structure of PRC1 bound to the microtubule.
Proc.Natl.Acad.Sci.USA, 113, 2016
5FUR
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BU of 5fur by Molmil
Structure of human TFIID-IIA bound to core promoter DNA
Descriptor: SUPER CORE PROMOTER, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1, ...
Authors:Louder, R.K, He, Y, Lopez-Blanco, J.R, Fang, J, Chacon, P, Nogales, E.
Deposit date:2016-01-29
Release date:2016-04-06
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly.
Nature, 531, 2016
4C9F
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BU of 4c9f by Molmil
Structure of SIGN-R1 in complex with Sulfodextran
Descriptor: 4-O-sulfo-alpha-D-glucopyranose, CALCIUM ION, CD209 ANTIGEN-LIKE PROTEIN B, ...
Authors:Silva-Martin, N, Bartual, S.G, Rodriguez, A, Ramirez, E, Chacon, P, Anthony, R.M, Park, C.G, Hermoso, J.A.
Deposit date:2013-10-02
Release date:2014-10-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Selective Recognition of Endogenous and Microbial Polysaccharides by Macrophage Receptor Sign-R1
Structure, 22, 2014
6ZP7
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BU of 6zp7 by Molmil
SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up open conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
Authors:Martinez, M, Marabini, R, Carazo, J.M.
Deposit date:2020-07-08
Release date:2020-07-29
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures.
Iucrj, 7, 2020
6ZOW
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BU of 6zow by Molmil
SARS-CoV-2 spike in prefusion state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
Authors:Martinez, M, Marabini, R, Carazo, J.M.
Deposit date:2020-07-07
Release date:2020-07-29
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures.
Iucrj, 7, 2020
6ZP5
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BU of 6zp5 by Molmil
SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up closed conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
Authors:Martinez, M, Marabini, R, Carazo, J.M.
Deposit date:2020-07-08
Release date:2020-07-29
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures.
Iucrj, 7, 2020
3DKX
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BU of 3dkx by Molmil
Crystal Structure of the replication initiator protein encoded on plasmid pMV158 (RepB), trigonal form, to 2.7 Ang resolution
Descriptor: CHLORIDE ION, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Boer, D.R, Ruiz-Maso, J.A, Blanco, A.G, Vives-Llacer, M, Uson, I, Gomis-Ruth, F.X, Espinosa, M, Del Solar, G, Coll, M.
Deposit date:2008-06-26
Release date:2009-06-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains
Embo J., 28, 2009
3DKY
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BU of 3dky by Molmil
Crystal Structure of the replication initiator protein encoded on plasmid pMV158 (RepB), tetragonal form, to 3.6 Ang resolution
Descriptor: MANGANESE (II) ION, Replication protein repB
Authors:Boer, D.R, Ruiz-Maso, J.A, Blanco, A.G, Vives-Llacer, M, Uson, I, Gomis-Ruth, F.X, Espinosa, M, Del Solar, G, Coll, M.
Deposit date:2008-06-26
Release date:2009-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains
Embo J., 28, 2009
7PIM
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BU of 7pim by Molmil
Partial structure of tyrosine hydroxylase lacking the first 35 residues in complex with dopamine.
Descriptor: FE (III) ION, L-DOPAMINE, Regulatory domain alpha-helix, ...
Authors:Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I.
Deposit date:2021-08-20
Release date:2021-12-22
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation.
Nat Commun, 13, 2022
8PW4
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BU of 8pw4 by Molmil
Protein p6 from bacteriophage phi29, C-terminal delta20 truncated version
Descriptor: Histone-like protein p6
Authors:Alcorlo Pages, M, Hermoso Dominguez, J.
Deposit date:2023-07-19
Release date:2024-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Flexible structural arrangement and DNA-binding properties of protein p6 from Bacillus subtillis phage phi 29.
Nucleic Acids Res., 52, 2024
8PW2
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BU of 8pw2 by Molmil
Protein p6 from bacteriophage phi29, C-terminal delta31 truncated version
Descriptor: Histone-like protein p6
Authors:Alcorlo Pages, M, Hermoso Dominguez, J.
Deposit date:2023-07-19
Release date:2024-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Flexible structural arrangement and DNA-binding properties of protein p6 from Bacillus subtillis phage phi 29.
Nucleic Acids Res., 52, 2024
3ZHG
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BU of 3zhg by Molmil
Crystallographic structure of the native mouse SIGN-R1 CRD domain
Descriptor: CALCIUM ION, CD209 ANTIGEN-LIKE PROTEIN B, SULFATE ION
Authors:Silva-Martin, N, Bartual, S.G, Hermoso, J.A.
Deposit date:2012-12-21
Release date:2014-01-15
Last modified:2020-03-11
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural Basis for Selective Recognition of Endogenous and Microbial Polysaccharides by Macrophage Receptor Sign-R1.
Structure, 22, 2014
4CDH
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BU of 4cdh by Molmil
Crystallographic structure of the Human Igg1 alpha 2-6 sialilated Fc-Fragment
Descriptor: IG GAMMA-1 CHAIN C REGION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Silva-Martin, N, Bartual, S.G, Hermoso, J.A.
Deposit date:2013-10-31
Release date:2014-11-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Selective Recognition of Endogenous and Microbial Polysaccharides by Macrophage Receptor Sign-R1
Structure, 22, 2014
4CAJ
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BU of 4caj by Molmil
Crystallographic structure of the mouse SIGN-R1 CRD domain in complex with sialic acid
Descriptor: CALCIUM ION, CD209 ANTIGEN-LIKE PROTEIN B, CHLORIDE ION, ...
Authors:Silva-Martin, N, Bartual, S.G, Hermoso, J.A.
Deposit date:2013-10-08
Release date:2014-10-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.191 Å)
Cite:Structural Basis for Selective Recognition of Endogenous and Microbial Polysaccharides by Macrophage Receptor Sign-R1
Structure, 22, 2014
6ZVP
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BU of 6zvp by Molmil
Atomic model of the EM-based structure of the full-length tyrosine hydroxylase in complex with dopamine (residues 40-497) in which the regulatory domain (residues 40-165) has been included only with the backbone atoms
Descriptor: FE (III) ION, L-DOPAMINE, Tyrosine 3-monooxygenase
Authors:Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I.
Deposit date:2020-07-27
Release date:2021-11-17
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation.
Nat Commun, 13, 2022
6ZZU
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BU of 6zzu by Molmil
Partial structure of the substrate-free tyrosine hydroxylase (apo-TH).
Descriptor: FE (III) ION, Tyrosine 3-monooxygenase
Authors:Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I.
Deposit date:2020-08-05
Release date:2021-11-17
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation.
Nat Commun, 13, 2022
7A2G
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BU of 7a2g by Molmil
Full-length structure of the substrate-free tyrosine hydroxylase (apo-TH).
Descriptor: FE (III) ION, Tyrosine 3-monooxygenase
Authors:Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Flydal, M.I, Martinez, A, Valpuesta, J.M.
Deposit date:2020-08-17
Release date:2021-12-01
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation.
Nat Commun, 13, 2022
6ZN2
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BU of 6zn2 by Molmil
Partial structure of tyrosine hydroxylase in complex with dopamine showing the catalytic domain and an alpha-helix from the regulatory domain involved in dopamine binding.
Descriptor: FE (III) ION, L-DOPAMINE, SER-LEU-ILE-GLU-ASP-ALA-ARG-LYS-GLU-ARG-GLU-ALA-ALA-VAL-ALA-ALA-ALA-ALA, ...
Authors:Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I.
Deposit date:2020-07-06
Release date:2021-12-08
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation.
Nat Commun, 13, 2022
6O9L
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BU of 6o9l by Molmil
Human holo-PIC in the closed state
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I.
Deposit date:2019-03-14
Release date:2019-05-29
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019

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