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1UQS
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BU of 1uqs by Molmil
The Crystal Structure of Human CD1b with a Bound Bacterial Glycolipid
Descriptor: BETA-2-MICROGLOBULIN, GLUCOSE MONOMYCOLATE, T-CELL SURFACE GLYCOPROTEIN CD1B
Authors:Batuwangala, T, Shepherd, D, Gadola, S.D, Gibson, K.J.C, Zaccai, N.R, Besra, G.S, Cerundolo, V, Jones, E.Y.
Deposit date:2003-10-16
Release date:2003-10-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The crystal structure of human CD1b with a bound bacterial glycolipid.
J Immunol., 172, 2004
1GZQ
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BU of 1gzq by Molmil
CD1b in complex with Phophatidylinositol
Descriptor: 2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE, B2-MICROGLOBULIN, DOCOSANE, ...
Authors:Gadola, S.D, Zaccai, N.R, Harlos, K, Shepherd, D, Ritter, G, Schmidt, R.R, Jones, E.Y, Cerundolo, V.
Deposit date:2002-05-24
Release date:2002-07-31
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structure of Human Cd1B with Bound Ligands at 2.3 A, a Maze for Alkyl Chains
Nat.Immunol., 3, 2002
1GZP
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BU of 1gzp by Molmil
CD1b in complex with GM2 ganglioside
Descriptor: B2-MICROGLOBULIN, DOCOSANE, DODECANE, ...
Authors:Gadola, S.D, Zaccai, N.R, Harlos, K, Shepherd, D, Ritter, G, Schmidt, R.R, Jones, E.Y, Cerundolo, V.
Deposit date:2002-05-24
Release date:2002-07-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.
Nat. Immunol., 3, 2002
3BEW
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BU of 3bew by Molmil
10mer Crystal Structure of chicken MHC class I haplotype B21
Descriptor: 10-mer from Tubulin beta-6 chain, Beta-2-microglobulin, Major histocompatibility complex class I glycoprotein haplotype B21
Authors:Koch, M, Camp, S, Collen, T, Avila, D, Salomonsen, J, Wallny, H.J, van Hateren, A, Hunt, L, Jacob, J.P, Johnston, F, Marston, D.A, Shaw, I, Dunbar, P.R, Cerundolo, V, Jones, E.Y, Kaufman, J.
Deposit date:2007-11-20
Release date:2008-01-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of an MHC class I molecule from b21 chickens illustrate promiscuous Peptide binding
Immunity, 27, 2007
2BNU
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BU of 2bnu by Molmil
Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Descriptor: T-CELL RECEPTOR ALPHA CHAIN C REGION, T-CELL RECEPTOR BETA CHAIN C REGION
Authors:Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, Van Der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
Deposit date:2005-04-04
Release date:2005-05-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines.
J.Exp.Med., 201, 2005
2BNR
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BU of 2bnr by Molmil
Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ...
Authors:Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
Deposit date:2005-03-31
Release date:2005-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
2BNQ
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BU of 2bnq by Molmil
Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ...
Authors:Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
Deposit date:2005-03-31
Release date:2005-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
3GJF
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BU of 3gjf by Molmil
Rational development of high-affinity T-cell receptor-like antibodies
Descriptor: Antibody heavy chain, Antibody light chain, Beta-2-microglobulin, ...
Authors:Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E, Kleber, S, Stenner-Liewen, F, Bauer, S, McMichael, A, Knuth, A, Abken, H, Hombach, A.A, Cerundolo, V, Jones, E.Y, Renner, C.
Deposit date:2009-03-08
Release date:2009-04-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
3GJE
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BU of 3gje by Molmil
Rational development of high-affinity T-cell receptor-like antibodies
Descriptor: Fab Heavy Chain, Fab Light Chain
Authors:Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E, Kleber, S, Stenner-Liewen, F, Bauer, S, McMichael, A, Knuth, A, Abken, H, Hombach, A.A, Cerundolo, V, Jones, E.Y, Renner, C.
Deposit date:2009-03-08
Release date:2009-04-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
1ZT4
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BU of 1zt4 by Molmil
The crystal structure of human CD1d with and without alpha-Galactosylceramide
Descriptor: Beta-2-microglobulin, N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE, T-cell surface glycoprotein CD1d
Authors:Koch, M, Stronge, V.S, Shepherd, D, Gadola, S.D, Mathew, B, Ritter, G, Fersht, A.R, Besra, G.S, Schmidt, R.R, Jones, E.Y, Cerundolo, V, Structural Proteomics in Europe (SPINE)
Deposit date:2005-05-26
Release date:2005-07-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of human CD1d with and without alpha-galactosylceramide
Nat.Immunol., 6, 2005
2CDF
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BU of 2cdf by Molmil
Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide-specific T cell receptors (TCR 5E)
Descriptor: TCR 5E
Authors:Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y.
Deposit date:2006-01-23
Release date:2006-03-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
2CDG
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BU of 2cdg by Molmil
Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide-specific T cell receptors (TCR 5B)
Descriptor: TCR 5E
Authors:Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y.
Deposit date:2006-01-23
Release date:2006-03-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
2CDE
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BU of 2cde by Molmil
Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide specific T cell receptors - iNKT-TCR
Descriptor: INKT-TCR
Authors:Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y.
Deposit date:2006-01-23
Release date:2006-03-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
3BEV
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BU of 3bev by Molmil
11mer Structure of an MHC class I molecule from B21 chickens illustrate promiscuous peptide binding
Descriptor: Beta-2-microglobulin, Hemoglobin subunit alpha-A, Major histocompatibility complex class I glycoprotein haplotype B21
Authors:Koch, M, Kaufman, J, Jones, Y.
Deposit date:2007-11-20
Release date:2008-01-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of an MHC class I molecule from b21 chickens illustrate promiscuous Peptide binding
Immunity, 27, 2007
6PVC
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BU of 6pvc by Molmil
Structure of human MAIT A-F7 TCR in complex with human MR1-DB28
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Awad, W, Rossjohn, J.
Deposit date:2019-07-20
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Ligand-dependent downregulation of MR1 cell surface expression.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PVD
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BU of 6pvd by Molmil
Structure of human MAIT A-F7 TCR in complex with human MR1-NV18.1
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Awad, W, Rossjohn, J.
Deposit date:2019-07-20
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Ligand-dependent downregulation of MR1 cell surface expression.
Proc.Natl.Acad.Sci.USA, 117, 2020
3HAE
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BU of 3hae by Molmil
Rational development of high-affinity T-cell receptor-like antibodies
Descriptor: Antibody heavy chain, Antibody light chain, Beta-2-microglobulin, ...
Authors:Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E.
Deposit date:2009-05-01
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
3KLA
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BU of 3kla by Molmil
Ca2+ release from the endoplasmic reticulum of NY-ESO-1 specific T cells is modulated by the affinity of T cell receptor and by the use of the CD8 co-receptor
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Chen, J.L, Morgan, A.J, Stewart-Jones, G, Shepherd, D, Bossi, G, Wooldridge, L.
Deposit date:2009-11-07
Release date:2010-02-16
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Ca2+ Release from the Endoplasmic Reticulum of NY-ESO-1-Specific T Cells Is Modulated by the Affinity of TCR and by the Use of the CD8 Coreceptor.
J.Immunol., 184, 2010
6SS4
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BU of 6ss4 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021181
Descriptor: Arginase-2, mitochondrial, Fab C0021181 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS2
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BU of 6ss2 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021158
Descriptor: Arginase-2, mitochondrial, Fab C0021158 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS5
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BU of 6ss5 by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0020187
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SS0
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BU of 6ss0 by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021181
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fab C0021181 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS6
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BU of 6ss6 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0020187
Descriptor: Arginase-2, mitochondrial, Fab C0020187 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SRV
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BU of 6srv by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021144
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2020-09-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SRX
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BU of 6srx by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021158
Descriptor: ACETATE ION, CHLORIDE ION, Fab C0021158 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12

 

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