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2BNQ
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STRUCTURAL AND KINETIC BASIS FOR HEIGHTENED IMMUNOGENICITY OF T CELL VACCINES
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, BETA-2-MICROGLOBULIN, SYNTHETIC PEPTIDE, ...
Authors:Chen, J.-L., Stewart-Jones, G., Bossi, G., Lissin, N.M., Wooldridge, L., Choi, E.M.L., Held, G., Dunbar, P.R., Esnouf, R.M., Sami, M., Boultier, J.M., Rizkallah, P.J., Renner, C., Sewell, A., van der Merwe, P.A., Jackobsen, B.K., Griffiths, G., Jones, E.Y., Cerundolo, V.
Deposit date:2005-03-31
Release date:2005-05-23
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
2BNR
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STRUCTURAL AND KINETIC BASIS FOR HEIGHTENED IMMUNOGENICITY OF T CELL VACCINES
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, BETA-2-MICROGLOBULIN, SYNTHETIC PEPTIDE, ...
Authors:Chen, J.-L., Stewart-Jones, G., Bossi, G., Lissin, N.M., Wooldridge, L., Choi, E.M.L., Held, G., Dunbar, P.R., Esnouf, R.M., Sami, M., Boultier, J.M., Rizkallah, P.J., Renner, C., Sewell, A., van der Merwe, P.A., Jackobsen, B.K., Griffiths, G., Jones, E.Y., Cerundolo, V.
Deposit date:2005-03-31
Release date:2005-05-23
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
2BNU
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STRUCTURAL AND KINETIC BASIS FOR HEIGHTENED IMMUNOGENICITY OF T CELL VACCINES
Descriptor:T-CELL RECEPTOR ALPHA CHAIN C REGION, T-CELL RECEPTOR BETA CHAIN C REGION
Authors:Chen, J.-L., Stewart-Jones, G., Bossi, G., Lissin, N.M., Wooldridge, L., Choi, E.M.L., Held, G., Dunbar, P.R., Esnouf, R.M., Sami, M., Boultier, J.M., Rizkallah, P.J., Renner, C., Sewell, A., Van Der Merwe, P.A., Jackobsen, B.K., Griffiths, G., Jones, E.Y., Cerundolo, V.
Deposit date:2005-04-04
Release date:2005-05-24
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines.
J.Exp.Med., 201, 2005
1GZP
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CD1B IN COMPLEX WITH GM2 GANGLIOSIDE
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD1B, B2-MICROGLOBULIN, N-[(1S,2S)-2-HYDROXY-1-({[(2R,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2-YL]OXY}METHYL)OCTADECYL]OCTADECANAMIDE, ...
Authors:Gadola, S.D., Zaccai, N.R., Harlos, K., Shepherd, D., Ritter, G., Schmidt, R.R., Jones, E.Y., Cerundolo, V.
Deposit date:2002-05-24
Release date:2002-07-31
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.
Nat. Immunol., 3, 2002
1GZQ
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CD1B IN COMPLEX WITH PHOPHATIDYLINOSITOL
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD1B, B2-MICROGLOBULIN, 2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE, ...
Authors:Gadola, S.D., Zaccai, N.R., Harlos, K., Shepherd, D., Ritter, G., Schmidt, R.R., Jones, E.Y., Cerundolo, V.
Deposit date:2002-05-24
Release date:2002-07-31
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structure of Human Cd1B with Bound Ligands at 2.3 A, a Maze for Alkyl Chains
Nat.Immunol., 3, 2002
1UQS
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THE CRYSTAL STRUCTURE OF HUMAN CD1B WITH A BOUND BACTERIAL GLYCOLIPID
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD1B, BETA-2-MICROGLOBULIN, GLUCOSE MONOMYCOLATE
Authors:Batuwangala, T., Shepherd, D., Gadola, S.D., Gibson, K.J.C., Zaccai, N.R., Besra, G.S., Cerundolo, V., Jones, E.Y.
Deposit date:2003-10-16
Release date:2003-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Crystal Structure of Human Cd1B with a Bound Bacterial Glycolipid
J.Immunol., 172, 2004
1ZT4
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THE CRYSTAL STRUCTURE OF HUMAN CD1D WITH AND WITHOUT ALPHA-GALACTOSYLCERAMIDE
Descriptor:T-cell surface glycoprotein CD1d, Beta-2-microglobulin, N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE
Authors:Koch, M., Stronge, V.S., Shepherd, D., Gadola, S.D., Mathew, B., Ritter, G., Fersht, A.R., Besra, G.S., Schmidt, R.R., Jones, E.Y., Cerundolo, V., Structural Proteomics in Europe (SPINE)
Deposit date:2005-05-26
Release date:2005-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of human CD1d with and without alpha-galactosylceramide
Nat.Immunol., 6, 2005
2CDE
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STRUCTURE AND BINDING KINETICS OF THREE DIFFERENT HUMAN CD1D-ALPHA- GALACTOSYLCERAMIDE SPECIFIC T CELL RECEPTORS - INKT-TCR
Descriptor:INKT-TCR
Authors:Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y.
Deposit date:2006-01-23
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
2CDF
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STRUCTURE AND BINDING KINETICS OF THREE DIFFERENT HUMAN CD1D-ALPHA- GALACTOSYLCERAMIDE-SPECIFIC T CELL RECEPTORS (TCR 5E)
Descriptor:TCR 5E
Authors:Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y.
Deposit date:2006-01-23
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
2CDG
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STRUCTURE AND BINDING KINETICS OF THREE DIFFERENT HUMAN CD1D-ALPHA- GALACTOSYLCERAMIDE-SPECIFIC T CELL RECEPTORS (TCR 5B)
Descriptor:TCR 5E
Authors:Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y.
Deposit date:2006-01-23
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
3BEW
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10MER CRYSTAL STRUCTURE OF CHICKEN MHC CLASS I HAPLOTYPE B21
Descriptor:Major histocompatibility complex class I glycoprotein haplotype B21, Beta-2-microglobulin, 10-mer from Tubulin beta-6 chain
Authors:Koch, M., Camp, S., Collen, T., Avila, D., Salomonsen, J., Wallny, H.J., van Hateren, A., Hunt, L., Jacob, J.P., Johnston, F., Marston, D.A., Shaw, I., Dunbar, P.R., Cerundolo, V., Jones, E.Y., Kaufman, J.
Deposit date:2007-11-20
Release date:2008-01-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of an MHC class I molecule from b21 chickens illustrate promiscuous Peptide binding
Immunity, 27, 2007
3GJE
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RATIONAL DEVELOPMENT OF HIGH-AFFINITY T-CELL RECEPTOR-LIKE ANTIBODIES
Descriptor:Fab Light Chain, Fab Heavy Chain
Authors:Stewart-Jones, G., Wadle, A., Hombach, A., Shenderov, E., Held, G., Fischer, E., Kleber, S., Stenner-Liewen, F., Bauer, S., McMichael, A., Knuth, A., Abken, H., Hombach, A.A., Cerundolo, V., Jones, E.Y., Renner, C.
Deposit date:2009-03-08
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
3GJF
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RATIONAL DEVELOPMENT OF HIGH-AFFINITY T-CELL RECEPTOR-LIKE ANTIBODIES
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Stewart-Jones, G., Wadle, A., Hombach, A., Shenderov, E., Held, G., Fischer, E., Kleber, S., Stenner-Liewen, F., Bauer, S., McMichael, A., Knuth, A., Abken, H., Hombach, A.A., Cerundolo, V., Jones, E.Y., Renner, C.
Deposit date:2009-03-08
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
3BEV
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11MER STRUCTURE OF AN MHC CLASS I MOLECULE FROM B21 CHICKENS ILLUSTRATE PROMISCUOUS PEPTIDE BINDING
Descriptor:Major histocompatibility complex class I glycoprotein haplotype B21, Beta-2-microglobulin, Hemoglobin subunit alpha-A
Authors:Koch, M., Kaufman, J., Jones, Y.
Deposit date:2007-11-20
Release date:2008-01-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of an MHC class I molecule from b21 chickens illustrate promiscuous Peptide binding
Immunity, 27, 2007
3HAE
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RATIONAL DEVELOPMENT OF HIGH-AFFINITY T-CELL RECEPTOR-LIKE ANTIBODIES
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Stewart-Jones, G., Wadle, A., Hombach, A., Shenderov, E., Held, G., Fischer, E.
Deposit date:2009-05-01
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
3KLA
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CA2+ RELEASE FROM THE ENDOPLASMIC RETICULUM OF NY-ESO-1 SPECIFIC T CELLS IS MODULATED BY THE AFFINITY OF T CELL RECEPTOR AND BY THE USE OF THE CD8 CO-RECEPTOR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Chen, J.L., Morgan, A.J., Stewart-Jones, G., Shepherd, D., Bossi, G., Wooldridge, L.
Deposit date:2009-11-07
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Ca2+ Release from the Endoplasmic Reticulum of NY-ESO-1-Specific T Cells Is Modulated by the Affinity of TCR and by the Use of the CD8 Coreceptor.
J.Immunol., 184, 2010