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3S8S
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CRYSTAL STRUCTURE OF THE RRM DOMAIN OF HUMAN SETD1A
Descriptor:Histone-lysine N-methyltransferase SETD1A, UNKNOWN ATOM OR ION
Authors:Chao, X., Tempel, W., Bian, C., Cerovina, T., Walker, J.R., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-05-30
Release date:2011-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the RRM domain of human SETD1A
to be published
4FU6
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CRYSTAL STRUCTURE OF THE PSIP1 PWWP DOMAIN
Descriptor:PC4 and SFRS1-interacting protein, SULFATE ION, GLYCEROL, ...
Authors:Qin, S., Tempel, W., Xu, C., Wu, H., Dong, A., Cerovina, T., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2012-06-28
Release date:2012-08-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the PSIP1 PWWP domain
TO BE PUBLISHED
4HBD
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CRYSTAL STRUCTURE OF KANK2 ANKYRIN REPEATS
Descriptor:KN motif and ankyrin repeat domain-containing protein 2, UNKNOWN ATOM OR ION
Authors:Xu, C., Tempel, W., Cerovina, T., El Bakkouri, M., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2012-09-27
Release date:2012-12-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of KANK2 ankyrin repeats
To be Published
5UPD
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METHYLTRANSFERASE DOMAIN OF HUMAN WOLF-HIRSCHHORN SYNDROME CANDIDATE 1-LIKE PROTEIN 1 (WHSC1L1)
Descriptor:Histone-lysine N-methyltransferase NSD3, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION, ...
Authors:Tempel, W., Yu, W., Dong, A., Cerovina, T., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2017-02-02
Release date:2017-02-15
Last modified:2017-03-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Methyltransferase domain of human Wolf-Hirschhorn Syndrome Candidate 1-Like protein 1 (WHSC1L1)
To Be Published
5C0M
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CRYSTAL STRUCTURE OF SGF29 TANDEM TUDOR DOMAIN IN COMPLEX WITH A CARBA CONTAINING PEPTIDE
Descriptor:SAGA-associated factor 29 homolog, Carba-containing peptide, SULFATE ION, ...
Authors:Dong, A., Xu, C., Tempel, W., Cerovina, T., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2015-06-12
Release date:2015-07-01
Last modified:2016-03-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins.
Nat Commun, 6, 2015
5TEE
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CRYSTAL STRUCTURE OF GEMIN5 WD40 REPEATS IN APO FORM
Descriptor:Gem-associated protein 5, GLYCEROL, UNKNOWN ATOM OR ION, ...
Authors:Chao, X., Tempel, W., Bian, C., Cerovina, T., He, H., Walker, J.R., Seitova, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2016-09-21
Release date:2016-10-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Genes Dev., 30, 2016
5TEF
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CRYSTAL STRUCTURE OF GEMIN5 WD40 REPEATS IN COMPLEX WITH M7GPPPG
Descriptor:Gem-associated protein 5, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, GLYCEROL, ...
Authors:Chao, X., Tempel, W., Bian, C., He, H., Cerovina, T., Seitova, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2016-09-21
Release date:2016-10-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Genes Dev., 30, 2016
5THA
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GEMIN5 WD40 REPEATS IN COMPLEX WITH A GUANOSYL MOIETY
Descriptor:Gem-associated protein 5, UNKNOWN ATOM OR ION, DIGUANOSINE-5'-TRIPHOSPHATE
Authors:Chao, X., Tempel, W., Bian, C., Cerovina, T., He, H., Seitova, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2016-09-29
Release date:2016-10-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Genes Dev., 30, 2016
4HP1
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CRYSTAL STRUCTURE OF TET3 IN COMPLEX WITH A NON-CPG DSDNA
Descriptor:DNA (5'-D(*GP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*C)-3'), LOC100036628 protein, ZINC ION
Authors:Chao, X., Tempel, W., Bian, C., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2012-10-23
Release date:2012-12-05
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.
Cell(Cambridge,Mass.), 151, 2012
4HP3
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CRYSTAL STRUCTURE OF TET3 IN COMPLEX WITH A CPG DSDNA
Descriptor:DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), LOC100036628 protein, UNKNOWN ATOM OR ION, ...
Authors:Chao, X., Tempel, W., Bian, C., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2012-10-23
Release date:2012-12-05
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.
Cell(Cambridge,Mass.), 151, 2012
4O61
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STRUCTURE OF HUMAN ALKBH5 CRYSTALLIZED IN THE PRESENCE OF CITRATE
Descriptor:RNA demethylase ALKBH5, GLYCEROL, CITRIC ACID, ...
Authors:Tempel, W., Chao, X., Liu, K., Dong, A., Cerovina, T., He, H., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2013-12-20
Release date:2014-02-26
Last modified:2015-07-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.
J.Biol.Chem., 289, 2014
4OCT
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CRYSTAL STRUCTURE OF HUMAN ALKBH5 CRYSTALLIZED IN THE PRESENCE OF MN^{2+} AND 2-OXOGLUTARATE
Descriptor:RNA demethylase ALKBH5, MANGANESE (II) ION, 2-OXOGLUTARIC ACID, ...
Authors:Tempel, W., Chao, X., Liu, K., Dong, A., Cerovina, T., He, H., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2014-01-09
Release date:2014-04-16
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.
J.Biol.Chem., 289, 2014