Author results

1N52
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CAP BINDING COMPLEX
Descriptor:80 kDa nuclear cap binding protein, 20 kDa nuclear cap binding protein, MAGNESIUM ION, ...
Authors:Calero, G., Wilson, K., Ly, T., Rios-Steiner, J., Clardy, J., Cerione, R.
Deposit date:2002-11-04
Release date:2003-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.
Nat.Struct.Biol., 9, 2002
1N54
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CAP BINDING COMPLEX M7GPPPG FREE
Descriptor:80 kDa nuclear cap binding protein, 20 kDa nuclear cap binding protein, GLYCEROL
Authors:Calero, G., Wilson, K., Ly, T., Rios-Steiner, J., Clardy, J., Cerione, R.
Deposit date:2002-11-04
Release date:2003-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.
Nat.Struct.Biol., 9, 2002
5FI2
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CRYSTAL STRUCTURE OF HUMAN GAC IN COMPLEX WITH INHIBITOR UPGL_00009: 2-PHENYL-~{N}-[5-[[(3~{R})-1-[5-(2-PHENYLETHANOYLAMINO)-1,3,4-THIADIAZOL- 2-YL]PYRROLIDIN-3-YL]AMINO]-1,3,4-THIADIAZOL-2-YL]ETHANAMIDE
Descriptor:Glutaminase kidney isoform, mitochondrial, 2-phenyl-~{N}-[5-[[(3~{R})-1-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide
Authors:Huang, Q., Cerione, R.
Deposit date:2015-12-22
Release date:2016-05-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Design and evaluation of novel glutaminase inhibitors.
Bioorg.Med.Chem., 24, 2016
5FI6
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CRYSTAL STRUCTURE OF HUMAN GAC IN COMPLEX WITH INHIBITOR UPGL_00011: 2-PHENYL-~{N}-[5-[[(3~{S})-1-[5-(2-PHENYLETHANOYLAMINO)-1,3,4-THIADIAZOL-2-YL]PYRROLIDIN-3-YL]AMINO]-1,3,4-THIADIAZOL-2-YL]ETHANAMIDE
Descriptor:Glutaminase kidney isoform, mitochondrial, 2-phenyl-~{N}-[5-[[(3~{S})-1-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide
Authors:Huang, Q., Cerione, R.
Deposit date:2015-12-22
Release date:2016-05-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Design and evaluation of novel glutaminase inhibitors.
Bioorg.Med.Chem., 24, 2016
5FI7
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CRYSTAL STRUCTURE OF HUMAN GAC IN COMPLEX WITH INHIBITOR UPGL_00015: 2-PHENYL-~{N}-[5-[(3~{S})-3-[[5-(2-PHENYLETHANOYLAMINO)-1,3,4-THIADIAZOL-2-YL]OXY]PYRROLIDIN-1-YL]-1,3,4-THIADIAZOL-2-YL]ETHANAMIDE
Descriptor:Glutaminase kidney isoform, mitochondrial, 2-phenyl-~{N}-[5-[(3~{S})-3-[[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]ethanamide
Authors:Huang, Q., Cerione, R.
Deposit date:2015-12-22
Release date:2016-05-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Design and evaluation of novel glutaminase inhibitors.
Bioorg.Med.Chem., 24, 2016
5I94
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE C IN COMPLEX WITH THE INHIBITOR UPGL-00019
Descriptor:Glutaminase kidney isoform, mitochondrial, 2-phenyl-N-{5-[4-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide
Authors:Huang, Q., Cerione, R.
Deposit date:2016-02-19
Release date:2016-05-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.983 Å)
Cite:Design and evaluation of novel glutaminase inhibitors.
Bioorg.Med.Chem., 24, 2016
1AN0
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CDC42HS-GDP COMPLEX
Descriptor:CDC42HS-GDP, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Kongsaeree, P., Cerione, R., Clardy, J.
Deposit date:1997-06-26
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure Determination of Cdc42Hs and Gdp Complex
To be Published
2NGR
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TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP.
Descriptor:PROTEIN (GTP BINDING PROTEIN (G25K)), PROTEIN (GTPASE ACTIVATING PROTEIN (RHG)), MAGNESIUM ION, ...
Authors:Nassar, N., Hoffman, G., Clardy, J., Cerione, R.
Deposit date:1998-07-31
Release date:1999-01-06
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
Nat.Struct.Biol., 5, 1998