Author results

7KES
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CRYSTAL STRUCTURE OF META-AAC0038, AN ENVIRONMENTAL AMINOGLYCOSIDE RESISTANCE ENZYME, MUTANT H168A IN COMPLEX WITH APRAMYCIN AND COA
Descriptor:Aminoglycoside N(3)-acetyltransferase, GLYCEROL, COENZYME A, ...
Authors:Stogios, P.J., Skarina, T., Michalska, K., Xu, Z., Yim, V., Savchenko, A., Joachimiak, A., Satchell, K.J., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-10-12
Release date:2020-10-21
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in complex with apramycin and CoA
To Be Published
7KAG
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CRYSTAL STRUCTURE OF THE UBIQUITIN-LIKE DOMAIN 1 (UBL1) OF NSP3 FROM SARS-COV-2
Descriptor:Non-structural protein 3, 1,2-ETHANEDIOL, SULFATE ION
Authors:Stogios, P.J., Skarina, T., Chang, C., Kim, Y., Di Leo, R., Savchenko, A., Joachimiak, A., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-30
Release date:2020-10-14
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Crystal structure of the ubiquitin-like domain 1 (Ubl1) of Nsp3 from SARS-CoV-2
To Be Published
7KB2
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PUTATIVE ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN FROM ENTEROBACTER CLOACAE
Descriptor:ANK_REP_REGION domain-containing protein, PENTAETHYLENE GLYCOL, ACETATE ION, ...
Authors:Osipiuk, J., Tesar, C., Endres, M., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-10-01
Release date:2020-10-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Putative ankyrin repeat domain-containing protein from Enterobacter cloacae
To Be Published
7KB3
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THE STRUCTURE OF A SENSOR DOMAIN OF A HISTIDINE KINASE (VXRA) FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961, 2ND FORM
Descriptor:Sensor histidine kinase, GLYCEROL, ACETATE ION, ...
Authors:Tan, K., Wu, R., Jedrzejczak, R., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-10-01
Release date:2020-10-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The structure of a sensor domain of a histidine kinase (VxrA) from Vibrio cholerae O1 biovar eltor str. N16961, 2nd form
To Be Published
7KB4
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THE STRUCTURE OF A SENSOR DOMAIN OF A HISTIDINE KINASE (VXRA) FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961, N239 DELETION MUTANT
Descriptor:Sensor histidine kinase, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ...
Authors:Tan, K., Wu, R., Jedrzejczak, R., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID), Center for Membrane Proteins of Infectious Diseases (MPID)
Deposit date:2020-10-01
Release date:2020-10-14
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:THE STRUCTURE OF A SENSOR DOMAIN OF A HISTIDINE KINASE (VxrA) FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961, N239 deletion mutant
To Be Published
7KB7
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THE STRUCTURE OF A SENSOR DOMAIN OF A HISTIDINE KINASE (VXRA) FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961, N239-T240 DELETION MUTANT
Descriptor:Sensor histidine kinase, 1,2-ETHANEDIOL, SULFATE ION, ...
Authors:Tan, K., Wu, R., Jedrzejczak, R., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID), Center for Membrane Proteins of Infectious Diseases (MPID)
Deposit date:2020-10-01
Release date:2020-10-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:THE STRUCTURE OF A SENSOR DOMAIN OF A HISTIDINE KINASE (VxrA) FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961, N239-T240 deletion mutant
To Be Published
7KB9
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THE STRUCTURE OF A SENSOR DOMAIN OF A HISTIDINE KINASE (VXRA) FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961, D238-T240 DELETION MUTANT
Descriptor:Sensor histidine kinase, GLYCEROL, 1,2-ETHANEDIOL
Authors:Tan, K., Wu, R., Jedrzejczak, R., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-10-01
Release date:2020-10-14
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:THE STRUCTURE OF A SENSOR DOMAIN OF A HISTIDINE KINASE (VxrA) FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961, D238-T240 deletion mutant
To Be Published
6V4N
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STRUCTURE OF HUMAN 1G05 FAB IN COMPLEX WITH INFLUENZA VIRUS NEURAMINIDASE FROM B/PHUKET/3073/2013
Descriptor:Neuraminidase, Antibody Fab heavy chain, Antibody Fab light chain, ...
Authors:Dai, Y.N., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-11-28
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 2020
6V4O
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STRUCTURE OF HUMAN 2E01 FAB IN COMPLEX WITH INFLUENZA VIRUS NEURAMINIDASE FROM B/PHUKET/3073/2013
Descriptor:Neuraminidase, Antibody Fab heavy chain, Antibody Fab light chain, ...
Authors:Dai, Y.N., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-11-28
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 2020
7K3N
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CRYSTAL STRUCTURE OF NSP1 FROM SARS-COV-2
Descriptor:Host translation inhibitor nsp1
Authors:Semper, C., Watanabe, N., Chang, C., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-11
Release date:2020-09-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of NSP1 from SARS-CoV-2
To be Published
7JX6
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STRUCTURE OF THE SARS-COV-2 ORF8 ENCODED ACCESSORY PROTEIN
Descriptor:ORF8 protein, SODIUM ION
Authors:Hall, P.D., Nelson, C.A., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-08-26
Release date:2020-09-23
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal Structure of the SARS-CoV-2 ORF8 Protein
To Be Published
7K1L
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CRYSTAL STRUCTURE OF NSP15 ENDORIBONUCLEASE FROM SARS COV-2 IN THE COMPLEX WITH URIDINE-2',3'-VANADATE
Descriptor:Uridylate-specific endoribonuclease, URIDINE-2',3'-VANADATE, ACETATE ION, ...
Authors:Kim, Y., Maltseva, N., Jedrzejczak, R., Endres, M., Welk, L., Chang, C., Michalska, K., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-07
Release date:2020-09-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with Uridine-2',3'-Vanadate
To Be Published
7K1O
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CRYSTAL STRUCTURE OF NSP15 ENDORIBONUCLEASE FROM SARS COV-2 IN THE COMPLEX WITH URIDINE-3',5'-DIPHOSPHATE
Descriptor:Uridylate-specific endoribonuclease, 1-(3,5-di-O-phosphono-alpha-L-xylofuranosyl)pyrimidine-2,4(1H,3H)-dione, 1,2-ETHANEDIOL
Authors:Kim, Y., Maltseva, N., Jedrzejczak, R., Endres, M., Welk, L., Chang, C., Michalska, K., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-08
Release date:2020-09-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with Uridine-3',5'-Diphosphate
To Be Published
7K3M
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CRYSTAL STRUCTURE OF THE BETA LACTAMASE CLASS D FROM CHITINOPHAGA PINENSIS BY SERIAL CRYSTALLOGRAPHY
Descriptor:Beta-lactamase
Authors:Kim, Y., Sherrell, D., Johnson, J., Lavens, A., Maltseva, N., Endres, M., Babnigg, G., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-11
Release date:2020-09-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Beta Lactamase Class D from Chitinophaga pinensis by Serial Crystallography
To Be Published
7JM0
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE RESISTANCE ENZYME APMA, APOENZYME
Descriptor:Aminocyclitol acetyltransferase ApmA, SULFATE ION
Authors:Stogios, P.J., Evdokimova, E., Di Leo, R., Bordeleau, E., Wright, G.D., Savchenko, A., Joachimiak, A., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-30
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structure of aminoglycoside resistance enzyme ApmA, apoenzyme
To Be Published
7JM1
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE RESISTANCE ENZYME APMA, COMPLEX WITH ACETYL-COA
Descriptor:Aminocyclitol acetyltransferase ApmA, ACETYL COENZYME *A
Authors:Stogios, P.J., Evdokimova, E., Di Leo, R., Bordeleau, E., Wright, G.D., Savchenko, A., Joachimiak, A., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-30
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of aminoglycoside resistance enzyme ApmA, complex with acetyl-CoA
To Be Published
7JM2
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE RESISTANCE ENZYME APMA, COMPLEX WITH APRAMYCIN
Descriptor:Aminocyclitol acetyltransferase ApmA, APRAMYCIN, CHLORIDE ION
Authors:Stogios, P.J., Evdokimova, E., Di Leo, R., Bordeleau, E., Wright, G.D., Savchenko, A., Joachimiak, A., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-30
Release date:2020-09-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of aminoglycoside resistance enzyme ApmA, complex with apramycin
To Be Published
7JYY
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CRYSTAL STRUCTURE OF SARS-COV-2 NSP16/10 HETERODIMER IN COMPLEX WITH (M7GPPPA)PUPUPAPAPA (CAP-0) AND S-ADENOSYLMETHIONINE (SAM).
Descriptor:2'-O-methyltransferase, Non-structural protein 10, RNA (5'-D(*(M7G))-R(P*AP*UP*UP*A)-3'), ...
Authors:Minasov, G., Shuvalova, L., Rosas-Lemus, M., Kiryukhina, O., Brunzelle, J.S., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-01
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA)pUpUpApApA (Cap-0) and S-Adenosylmethionine (SAM).
To Be Published
7JZ0
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CRYSTAL STRUCTURE OF SARS-COV-2 NSP16/10 HETERODIMER IN COMPLEX WITH (M7GPPPA2M)PUPUPAPAPA (CAP-1) AND S-ADENOSYL-L-HOMOCYSTEINE (SAH).
Descriptor:2'-O-methyltransferase, Non-structural protein 10, RNA (5'-D(*(M7G))-R(P*(A2M)P*UP*U)-3'), ...
Authors:Minasov, G., Shuvalova, L., Rosas-Lemus, M., Kiryukhina, O., Brunzelle, J.S., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-01
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).
To Be Published
7JU7
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THE CRYSTAL STRUCTURE OF SARS-COV-2 MAIN PROTEASE IN COMPLEX WITH MASITINIB
Descriptor:3C-like proteinase, Masitinib, DIMETHYL SULFOXIDE, ...
Authors:Tan, K., Maltseva, N.I., Welk, L.F., Jedrzejczak, R.P., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-08-19
Release date:2020-09-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of SARS-CoV-2 Main Protease in complex with masitinib.
To Be Published
7JWN
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CRYSTAL STRUCTURE OF HUMAN SERUM ALBUMIN IN COMPLEX WITH KETOPROFEN
Descriptor:Albumin, CYSTEINE, MYRISTIC ACID, ...
Authors:Czub, M.P., Shabalin, I.G., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-08-25
Release date:2020-09-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Human Serum Albumin in complex with ketoprofen
To Be Published
6U6C
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CRYSTAL STRUCTURE OF TRYPTOPHAN SYNTHASE FROM M. TUBERCULOSIS - AMINOACRYLATE- AND GSK2-BOUND FORM
Descriptor:Tryptophan synthase alpha chain, Tryptophan synthase beta chain, FORMIC ACID, ...
Authors:Chang, C., Michalska, K., Maltseva, N.I., Jedrzejczak, R., McCarren, P., Nag, P.P., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-08-29
Release date:2020-09-02
Last modified:2020-09-30
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase.
Protein Sci., 29, 2020
6W79
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STRUCTURE OF SARS-COV MAIN PROTEASE BOUND TO POTENT BROAD-SPECTRUM NON-COVALENT INHIBITOR X77
Descriptor:Main protease, DIMETHYL SULFOXIDE, N-(4-tert-butylphenyl)-N-[(1R)-2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-1H-imidazole-4-carboxamide, ...
Authors:Mesecar, A.D., StJohn, S., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-03-18
Release date:2020-08-26
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:A taxonomically-driven approach to development of potent, broad-spectrum inhibitors of coronavirus main protease including SARS-CoV-2 (COVID-19)
To Be Published
7JHE
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ROOM TEMPERATURE STRUCTURE OF SARS-COV-2 NSP10/NSP16 METHYLTRANSFERASE IN A COMPLEX WITH 2'-O-METHYLATED M7GPPPA CAP-1 AND SAH DETERMINED BY FIXED-TARGET SERIAL CRYSTALLOGRAPHY
Descriptor:2'-O-methyltransferase, Non-structural protein 10, CHLORIDE ION, ...
Authors:Wilamowski, M., Sherrell, D.A., Minasov, G., Kim, Y., Shuvalova, L., Lavens, A., Chard, R., Rosas-Lemus, M., Maltseva, N., Jedrzejczak, R., Michalska, K., Satchell, K.J.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-20
Release date:2020-08-26
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with 2'-O-methylated m7GpppA Cap-1 and SAH Determined by Fixed-Target Serial Crystallography
To Be Published
7JIB
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ROOM TEMPERATURE CRYSTAL STRUCTURE OF NSP10/NSP16 FROM SARS-COV-2 WITH SUBSTRATES AND PRODUCTS OF 2'-O-METHYLATION OF THE CAP-1
Descriptor:2'-O-methyltransferase, Non-structural protein 10, CHLORIDE ION, ...
Authors:Wilamowski, M., Minasov, G., Kim, Y., Sherrell, D.A., Shuvalova, L., Lavens, A., Chard, R., Rosas-Lemus, M., Maltseva, N., Jedrzejczak, R., Michalska, K., Satchell, K.J.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-23
Release date:2020-08-26
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Room Temperature Crystal Structure of Nsp10/Nsp16 from SARS-CoV-2 with Substrates and Products of 2'-O-methylation of the Cap-1
To Be Published
170172
PDB entries from 2020-10-21