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6BBM
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BU of 6bbm by Molmil
Mechanisms of Opening and Closing of the Bacterial Replicative Helicase: The DnaB Helicase and Lambda P Helicase Loader Complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Replication protein P, Replicative DNA helicase
Authors:Chase, J, Catalano, A, Noble, A.J, Eng, E.T, Olinares, P.D.B, Molloy, K, Pakotiprapha, D, Samuels, M, Chain, B, des Georges, A, Jeruzalmi, D.
Deposit date:2017-10-18
Release date:2019-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Mechanisms of opening and closing of the bacterial replicative helicase.
Elife, 7, 2018
3UWL
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BU of 3uwl by Molmil
Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with 5-formyl tetrahydrofolate
Descriptor: 1,2-ETHANEDIOL, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, SULFATE ION, ...
Authors:Pozzi, C, Catalano, A, Cortesi, D, Luciani, R, Ferrari, S, Fritz, T, Costi, M.P, Mangani, S.
Deposit date:2011-12-02
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:The structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolism.
Acta Crystallogr.,Sect.D, 68, 2012
4O7U
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BU of 4o7u by Molmil
Etherocomplex of Enteroccocus faecalis thymidylate synthase with 5-hydroxymethilene-6-hydrofolic acid and the phtalimidic inhibitor SS7
Descriptor: 1,2-ETHANEDIOL, 4-{[(2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]oxy}-3,5-dimethylphenyl acetate, 5-HYDROXYMETHYLENE-6-HYDROFOLIC ACID, ...
Authors:Mangani, S, Pozzi, C.
Deposit date:2013-12-26
Release date:2014-12-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors.
Eur.J.Med.Chem., 123, 2016
5J7W
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BU of 5j7w by Molmil
Enterococcus faecalis thymidylate synthase complex with methotrexate
Descriptor: METHOTREXATE, SULFATE ION, Thymidylate synthase
Authors:Mangani, S, Pozzi, C.
Deposit date:2016-04-07
Release date:2016-09-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors.
Eur.J.Med.Chem., 123, 2016

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