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1YGM
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NMR STRUCTURE OF MISTIC
Descriptor:hypothetical protein BSU31320
Authors:Roosild, T.P., Greenwald, J., Vega, M., Castronovo, S., Riek, R., Choe, S.
Deposit date:2005-01-05
Release date:2005-03-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of Mistic, a membrane-integrating protein for membrane protein expression.
Science, 307, 2005
3P0E
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STRUCTURE OF HUPP2 IN AN ACTIVE CONFORMATION WITH BOUND 5-BENZYLACYCLOURIDINE
Descriptor:Uridine phosphorylase 2, 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION
Authors:Roosild, T.P., Castronovo, S., Villoso, A.
Deposit date:2010-09-28
Release date:2011-09-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity.
J.Struct.Biol., 176, 2011
3P0F
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STRUCTURE OF HUPP2 IN AN INACTIVE CONFORMATION WITH BOUND 5-BENZYLACYCLOURIDINE
Descriptor:Uridine phosphorylase 2, 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE, COBALT (II) ION, ...
Authors:Roosild, T.P., Castronovo, S., Villoso, A.
Deposit date:2010-09-28
Release date:2011-09-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity.
J.Struct.Biol., 176, 2011
3EYW
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF E. COLI KEFC IN COMPLEX WITH KEFF
Descriptor:C-terminal domain of Glutathione-regulated potassium-efflux system protein kefC fused to full length Glutathione-regulated potassium-efflux system ancillary protein kefF, FLAVIN MONONUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Roosild, T.P.
Deposit date:2008-10-22
Release date:2009-06-30
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:KTN (RCK) Domains Regulate K(+) Channels and Transporters by Controlling the Dimer-Hinge Conformation.
Structure, 17, 2009
2G60
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STRUCTURE OF ANTI-FLAG M2 FAB DOMAIN
Descriptor:anti-FLAG M2 Fab light chain, anti-FLAG M2 Fab heavy chain
Authors:Roosild, T.P.
Deposit date:2006-02-23
Release date:2006-09-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins.
Acta Crystallogr.,Sect.F, 62, 2006
3L9W
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KEFC C-TERMINAL DOMAIN IN COMPLEX WITH KEFF AND GSH
Descriptor:Glutathione-regulated potassium-efflux system protein kefC, linker, ancillary protein kefF, ...
Authors:Roosild, T.P.
Deposit date:2010-01-05
Release date:2010-11-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mechanism of ligand-gated potassium efflux in bacterial pathogens.
Proc.Natl.Acad.Sci.USA, 107, 2010
3L9X
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KEFC C-TERMINAL DOMAIN IN COMPLEX WITH KEFF AND ESG
Descriptor:Glutathione-regulated potassium-efflux system protein kefC, linker, ancillary protein kefF, ...
Authors:Roosild, T.P.
Deposit date:2010-01-05
Release date:2010-11-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of ligand-gated potassium efflux in bacterial pathogens.
Proc.Natl.Acad.Sci.USA, 107, 2010
3EUE
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CRYSTAL STRUCTURE OF LIGAND-FREE HUMAN URIDINE PHOSPHORYLASE 1 (HUPP1)
Descriptor:Uridine phosphorylase 1, MAGNESIUM ION, SULFATE ION
Authors:Roosild, T.P.
Deposit date:2008-10-09
Release date:2009-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy.
Bmc Struct.Biol., 9, 2009
3EUF
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CRYSTAL STRUCTURE OF BAU-BOUND HUMAN URIDINE PHOSPHORYLASE 1
Descriptor:Uridine phosphorylase 1, 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION
Authors:Roosild, T.P.
Deposit date:2008-10-10
Release date:2009-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy.
Bmc Struct.Biol., 9, 2009
3NBQ
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HUMAN URIDINE PHOSPHORYLASE 1 (HUPP1) WITH 5-FLUOROURACIL
Descriptor:Uridine phosphorylase 1, 5-FLUOROURACIL
Authors:Roosild, T.P.
Deposit date:2010-06-03
Release date:2010-10-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Active site conformational dynamics in human uridine phosphorylase 1.
Plos One, 5, 2010