Author results

5CCA
  • Download 5cca
  • View 5cca
Molmil generated image of 5cca
CRYSTAL STRUCTURE OF MTB TOXIN
Descriptor:Endoribonuclease MazF3
Authors:Cascio, D., Arbing, M., de Serrano, V., Eisenberg, D., Miallau, L., TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-07-01
Release date:2016-09-07
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of Mtb toxin
To Be Published
5HRY
  • Download 5hry
  • View 5hry
Molmil generated image of 5hry
COMPUTATIONALLY DESIGNED CYCLIC DIMER ANK3C2_1
Descriptor:ank3C2_1
Authors:Cascio, D., McNamara, D.E., Fallas, J.A., Baker, D., Yeates, T.O.
Deposit date:2016-01-24
Release date:2017-04-12
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
5HRZ
  • Download 5hrz
  • View 5hrz
Molmil generated image of 5hrz
COMPUTATIONALLY DESIGNED TRIMER 1NA0C3_3
Descriptor:TPR domain protein 1na0C3_3
Authors:Cascio, D., McNamara, D.E., Fallas, J.A., Baker, D., Yeates, T.O.
Deposit date:2016-01-24
Release date:2017-04-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
1RLC
  • Download 1rlc
  • View 1rlc
Molmil generated image of 1rlc
CRYSTAL STRUCTURE OF THE UNACTIVATED RIBULOSE 1, 5-BISPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE COMPLEXED WITH A TRANSITION STATE ANALOG, 2-CARBOXY-D-ARABINITOL 1,5-BISPHOSPHATE
Descriptor:RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (LARGE CHAIN), RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (SMALL CHAIN), 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE
Authors:Zhang, K.Y.J., Cascio, D., Eisenberg, D.
Deposit date:1993-08-04
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the unactivated ribulose 1,5-bisphosphate carboxylase/oxygenase complexed with a transition state analog, 2-carboxy-D-arabinitol 1,5-bisphosphate.
Protein Sci., 3, 1994
3RUB
  • Download 3rub
  • View 3rub
Molmil generated image of 3rub
CRYSTAL STRUCTURE OF THE UNACTIVATED FORM OF RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE FROM TOBACCO REFINED AT 2.0-ANGSTROMS RESOLUTION
Descriptor:RIBULOSE 1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE, FORM III, SULFATE ION, ...
Authors:Schreuder, H., Cascio, D., Curmi, P.M.G., Chapman, M.S., Suh, S.W., Eisenberg, D.S.
Deposit date:1990-05-25
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the unactivated form of ribulose-1,5-bisphosphate carboxylase/oxygenase from tobacco refined at 2.0-A resolution.
J.Biol.Chem., 267, 1992
1BYZ
  • Download 1byz
  • View 1byz
Molmil generated image of 1byz
DESIGNED PEPTIDE ALPHA-1, P1 FORM
Descriptor:PROTEIN (SYNTHETIC DESIGNED PEPTIDE "ALPHA-1"), ETHANOLAMINE, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Prive, G.G., Anderson, D.H., Wesson, L., Cascio, D., Eisenberg, D.
Deposit date:1998-10-20
Release date:1998-10-28
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Packed protein bilayers in the 0.90 A resolution structure of a designed alpha helical bundle.
Protein Sci., 8, 1999
1COS
  • Download 1cos
  • View 1cos
Molmil generated image of 1cos
CRYSTAL STRUCTURE OF A SYNTHETIC TRIPLE-STRANDED ALPHA-HELICAL BUNDLE
Descriptor:COILED SERINE
Authors:Lovejoy, B., Choe, S., Cascio, D., Mcrorie, D.K., Degrado, W., Eisenberg, D.
Deposit date:1993-01-22
Release date:1993-10-31
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a synthetic triple-stranded alpha-helical bundle.
Science, 259, 1993
3AL1
  • Download 3al1
  • View 3al1
Molmil generated image of 3al1
DESIGNED PEPTIDE ALPHA-1, RACEMIC P1BAR FORM
Descriptor:PROTEIN (D, L-ALPHA-1), (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Patterson, W.R., Anderson, D.H., Degrado, W.F., Cascio, D., Eisenberg, D.
Deposit date:1998-10-26
Release date:1998-11-04
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (0.75 Å)
Cite:Centrosymmetric bilayers in the 0.75 A resolution structure of a designed alpha-helical peptide, D,L-Alpha-1.
Protein Sci., 8, 1999
1ZUR
  • Download 1zur
  • View 1zur
Molmil generated image of 1zur
CRYSTAL STRUCTURE OF SPIN LABELED T4 LYSOZYME (V131R1F)
Descriptor:Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, CHLORIDE ION
Authors:Fleissner, M.R., Cascio, D., Sawaya, M.R., Hideg, K., Hubbell, W.L.
Deposit date:2005-05-31
Release date:2006-10-17
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of spin labeled T4 Lysozyme (V131R1F)
To be Published
1ZWN
  • Download 1zwn
  • View 1zwn
Molmil generated image of 1zwn
CRYSTAL STRUCTURE OF SPIN LABELED T4 LYSOZYME (V131R1B)
Descriptor:Lysozyme, S-[(1-oxyl-2,2,4,5,5-pentamethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, AZIDE ION, ...
Authors:Fleissner, M.R., Cascio, D., Sawaya, M.R., Hideg, K., Hubbell, W.L.
Deposit date:2005-06-03
Release date:2006-10-17
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of spin labeled T4 Lysozyme (V131R1B)
To be Published
1ZYT
  • Download 1zyt
  • View 1zyt
Molmil generated image of 1zyt
CRYSTAL STRUCTURE OF SPIN LABELED T4 LYSOZYME (A82R1)
Descriptor:Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, AZIDE ION, ...
Authors:Fleissner, M.R., Cascio, D., Sawaya, M.R., Hideg, K., Hubbell, W.L.
Deposit date:2005-06-10
Release date:2006-08-15
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (1.7 Å), EPR
Cite:Structural origin of weakly ordered nitroxide motion in spin-labeled proteins
Protein Sci., 18, 2009
2A4T
  • Download 2a4t
  • View 2a4t
Molmil generated image of 2a4t
CRYSTAL STRUCTURE OF SPIN LABELED T4 LYSOZYME (V131R7)
Descriptor:Lysozyme, S-[(4-bromo-1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, AZIDE ION, ...
Authors:Fleissner, M.R., Cascio, D., Sawaya, M.R., Hideg, K., Hubbell, W.L.
Deposit date:2005-06-29
Release date:2006-06-13
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of spin labeled T4 Lysozyme (V131R7
To be Published
2CUU
  • Download 2cuu
  • View 2cuu
Molmil generated image of 2cuu
CRYSTAL STRUCTURE OF SPIN LABELED T4 LYSOZYME (V131R1)
Descriptor:Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, AZIDE ION, ...
Authors:Fleissner, M.R., Cascio, D., Sawaya, M.R., Hideg, K., Hubbell, W.L.
Deposit date:2005-05-28
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural origin of weakly ordered nitroxide motion in spin-labeled proteins
Protein Sci., 18, 2009
5K7N
  • Download 5k7n
  • View 5k7n
Molmil generated image of 5k7n
MICROED STRUCTURE OF TAU VQIVYK PEPTIDE AT 1.1 A RESOLUTION
Descriptor:VQIVYK
Authors:de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (1.1 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7O
  • Download 5k7o
  • View 5k7o
Molmil generated image of 5k7o
MICROED STRUCTURE OF LYSOZYME AT 1.8 A RESOLUTION
Descriptor:Lysozyme C, CHLORIDE ION, SODIUM ION
Authors:de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (1.8 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7P
  • Download 5k7p
  • View 5k7p
Molmil generated image of 5k7p
MICROED STRUCTURE OF XYLANASE AT 2.3 A RESOLUTION
Descriptor:Endo-1,4-beta-xylanase 2, IODIDE ION
Authors:de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (2.3 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7Q
  • Download 5k7q
  • View 5k7q
Molmil generated image of 5k7q
MICROED STRUCTURE OF THAUMATIN AT 2.5 A RESOLUTION
Descriptor:Thaumatin-1
Authors:de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (2.5 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7R
  • Download 5k7r
  • View 5k7r
Molmil generated image of 5k7r
MICROED STRUCTURE OF TRYPSIN AT 1.7 A RESOLUTION
Descriptor:Cationic trypsin, CALCIUM ION
Authors:de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (1.7 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7S
  • Download 5k7s
  • View 5k7s
Molmil generated image of 5k7s
MICROED STRUCTURE OF PROTEINASE K AT 1.6 A RESOLUTION
Descriptor:Proteinase K, CALCIUM ION
Authors:de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (1.6 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7T
  • Download 5k7t
  • View 5k7t
Molmil generated image of 5k7t
MICROED STRUCTURE OF THERMOLYSIN AT 2.5 A RESOLUTION
Descriptor:Thermolysin, CALCIUM ION, ZINC ION, ...
Authors:de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (2.5 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
3DG1
  • Download 3dg1
  • View 3dg1
Molmil generated image of 3dg1
SEGMENT SSTNVG DERIVED FROM IAPP
Descriptor:SSTNVG from Islet Amyloid Polypeptide
Authors:Wiltzius, J.J., Sievers, S.A., Sawaya, M.R., Cascio, D., Eisenberg, D.
Deposit date:2008-06-12
Release date:2008-07-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).
Protein Sci., 17, 2008
3DGJ
  • Download 3dgj
  • View 3dgj
Molmil generated image of 3dgj
NNFGAIL SEGMENT FROM ISLET AMYLOID POLYPEPTIDE (IAPP OR AMYLIN)
Descriptor:NNFGAIL peptide
Authors:Wiltzius, J.J., Sievers, S.A., Sawaya, M.R., Cascio, D., Eisenberg, D.
Deposit date:2008-06-13
Release date:2008-07-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).
Protein Sci., 17, 2008
5IM4
  • Download 5im4
  • View 5im4
Molmil generated image of 5im4
CRYSTAL STRUCTURE OF DESIGNED TWO-COMPONENT SELF-ASSEMBLING ICOSAHEDRAL CAGE I52-32
Descriptor:6,7-dimethyl-8-ribityllumazine synthase, Phosphotransferase system, mannose/fructose-specific component IIA
Authors:Liu, Y.A., Cascio, D., Sawaya, M.R., Bale, J.B., Collazo, M.J., Thomas, C., Sheffler, W., King, N.P., Baker, D., Yeates, T.O.
Deposit date:2016-03-05
Release date:2016-07-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
5IM5
  • Download 5im5
  • View 5im5
Molmil generated image of 5im5
CRYSTAL STRUCTURE OF DESIGNED TWO-COMPONENT SELF-ASSEMBLING ICOSAHEDRAL CAGE I53-40
Descriptor:Designed Riboflavin synthase, Designed Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase
Authors:Liu, Y.A., Cascio, D., Sawaya, M.R., Bale, J.B., Collazo, M.J., Thomas, C., Sheffler, W., King, N.P., Baker, D., Yeates, T.O.
Deposit date:2016-03-05
Release date:2016-07-27
Last modified:2016-08-10
Method:X-RAY DIFFRACTION (3.699 Å)
Cite:Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
5IM6
  • Download 5im6
  • View 5im6
Molmil generated image of 5im6
CRYSTAL STRUCTURE OF DESIGNED TWO-COMPONENT SELF-ASSEMBLING ICOSAHEDRAL CAGE I32-28
Descriptor:Designed self-assembling icosahedral cage I32-28 trimeric subunit, Designed self-assembling icosahedral cage I32-28 dimeric subunit
Authors:Liu, Y.A., Cascio, D., Sawaya, M.R., Bale, J.B., Collazo, M.J., Thomas, C., Sheffler, W., King, N.P., Baker, D., Yeates, T.O.
Deposit date:2016-03-05
Release date:2016-07-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (5.588 Å)
Cite:Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016