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1D2R
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BU of 1d2r by Molmil
2.9 A CRYSTAL STRUCTURE OF LIGAND-FREE TRYPTOPHANYL-TRNA SYNTHETASE: DOMAIN MOVEMENTS FRAGMENT THE ADENINE NUCLEOTIDE BINDING SITE.
Descriptor: PROTEIN (TRYPTOPHANYL TRNA SYNTHETASE)
Authors:Ilyin, V.A, Carter Jr, C.W.
Deposit date:1999-09-27
Release date:2000-04-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:2.9 A crystal structure of ligand-free tryptophanyl-tRNA synthetase: domain movements fragment the adenine nucleotide binding site.
Protein Sci., 9, 2000
5EKD
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BU of 5ekd by Molmil
Human mitochondrial tryptophanyl-tRNA synthetase bound by indolmycin and Mn*ATP.
Descriptor: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Williams, T.L, Carter Jr, C.W.
Deposit date:2015-11-03
Release date:2016-11-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Binding of Mg2+ATP Enhances Inhibition of Human Mitochondrial Tryptophanyl-tRNA Synthetase by Indolmycin
To Be Published
2OV4
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BU of 2ov4 by Molmil
Crystal structure of B. stearothermophilus tryptophanyl tRNA synthetase in complex with adenosine tetraphosphate
Descriptor: ADENOSINE-5'-TETRAPHOSPHATE, ANILINE, CESIUM ION, ...
Authors:Retailleau, P, Carter Jr, C.W.
Deposit date:2007-02-12
Release date:2007-03-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Adenosine-5' Tetraphosphate: Evidence for Distributed Use of Catalytic Binding Energy in Amino Acid Activation by Class I Aminoacyl-tRNA Synthetases.
J.Mol.Biol., 369, 2007
1HIP
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BU of 1hip by Molmil
TWO-ANGSTROM CRYSTAL STRUCTURE OF OXIDIZED CHROMATIUM HIGH POTENTIAL IRON PROTEIN
Descriptor: HIGH POTENTIAL IRON PROTEIN, IRON/SULFUR CLUSTER
Authors:Carterjunior, C.W, Kraut, J, Freer, S.T, Xuong, N.-H, Alden, R.A, Bartsch, R.G.
Deposit date:1975-04-01
Release date:1976-11-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two-Angstrom crystal structure of oxidized Chromatium high potential iron protein.
J.Biol.Chem., 249, 1974
1CTU
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BU of 1ctu by Molmil
TRANSITION-STATE SELECTIVITY FOR A SINGLE OH GROUP DURING CATALYSIS BY CYTIDINE DEAMINASE
Descriptor: 4-HYDROXY-3,4-DIHYDRO-ZEBULARINE, CYTIDINE DEAMINASE, ZINC ION
Authors:Xiang, S, Short, S.A, Wolfenden, R, Carter, C.W.
Deposit date:1995-02-11
Release date:1995-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Transition-state selectivity for a single hydroxyl group during catalysis by cytidine deaminase.
Biochemistry, 34, 1995
1CTT
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BU of 1ctt by Molmil
TRANSITION-STATE SELECTIVITY FOR A SINGLE OH GROUP DURING CATALYSIS BY CYTIDINE DEAMINASE
Descriptor: 3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE NUCLEOSIDE, CYTIDINE DEAMINASE, ZINC ION
Authors:Xiang, S, Short, S.A, Wolfenden, R, Carter, C.W.
Deposit date:1995-02-11
Release date:1995-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Transition-state selectivity for a single hydroxyl group during catalysis by cytidine deaminase.
Biochemistry, 34, 1995
1CMY
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BU of 1cmy by Molmil
THE MUTATION BETA99 ASP-TYR STABILIZES Y-A NEW, COMPOSITE QUATERNARY STATE OF HUMAN HEMOGLOBIN
Descriptor: HEMOGLOBIN YPSILANTI (CARBONMONOXY) (ALPHA CHAIN), HEMOGLOBIN YPSILANTI (CARBONMONOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE
Authors:Smith, F.R, Lattman, E.E, Carter Junior, C.W.
Deposit date:1992-09-18
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:The mutation beta 99 Asp-Tyr stabilizes Y--a new, composite quaternary state of human hemoglobin.
Proteins, 10, 1991
3FI0
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BU of 3fi0 by Molmil
Crystal Structure Analysis of B. stearothermophilus Tryptophanyl-tRNA Synthetase Complexed with Tryptophan, AMP, and Inorganic Phosphate
Descriptor: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, TRYPTOPHAN, ...
Authors:Laowanapiban, P, Kapustina, M, Vonrhein, C, Delarue, M, Koehl, P, Carter Jr, C.W.
Deposit date:2008-12-10
Release date:2009-02-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Independent saturation of three TrpRS subsites generates a partially assembled state similar to those observed in molecular simulations.
Proc.Natl.Acad.Sci.Usa, 106, 2009
3FHJ
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BU of 3fhj by Molmil
Independent saturation of three TrpRS subsites generates a partially-assembled state similar to those observed in molecular simulations
Descriptor: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, TRYPTOPHAN, ...
Authors:Laowanapiban, P, Kapustina, M, Vonrhein, C, Delarue, M, Koehl, P, Carter Jr, C.W.
Deposit date:2008-12-09
Release date:2009-02-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Independent saturation of three TrpRS subsites generates a partially assembled state similar to those observed in molecular simulations.
Proc.Natl.Acad.Sci.Usa, 106, 2009
1AF2
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BU of 1af2 by Molmil
CRYSTAL STRUCTURE OF CYTIDINE DEAMINASE COMPLEXED WITH URIDINE
Descriptor: CYTIDINE DEAMINASE, URIDINE-5'-MONOPHOSPHATE, ZINC ION
Authors:Xiang, S, Carter, C.W.
Deposit date:1997-03-20
Release date:1997-07-07
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of the cytidine deaminase-product complex provides evidence for efficient proton transfer and ground-state destabilization.
Biochemistry, 36, 1997
1ALN
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BU of 1aln by Molmil
CRYSTAL STRUCTURE OF CYTIDINE DEAMINASE COMPLEXED WITH 3-DEAZACYTIDINE
Descriptor: 3-DEAZACYTIDINE, CYTIDINE DEAMINASE, ZINC ION
Authors:Xiang, S, Carter, C.W.
Deposit date:1997-06-02
Release date:1997-09-17
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cytidine deaminase complexed to 3-deazacytidine: a "valence buffer" in zinc enzyme catalysis.
Biochemistry, 35, 1996
5DK4
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BU of 5dk4 by Molmil
Crystal structure analysis of Tryptophanyl-trna synthetase from Bacillus stearothermophilus in complex with indolmycin and Mg*ATP
Descriptor: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Williams, T, Yin, W.Y, Carter Jr, C.W.
Deposit date:2015-09-02
Release date:2015-11-18
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Selective Inhibition of Bacterial Tryptophanyl-tRNA Synthetases by Indolmycin Is Mechanism-based.
J.Biol.Chem., 291, 2016
1MAW
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BU of 1maw by Molmil
Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with ATP in an Open Conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, TRYPTOPHAN-TRNA LIGASE
Authors:Retailleau, P, Huang, X, Yin, Y, Hu, M, Weinreb, V, Vachette, P, Vonrhein, C, Bricogne, G, Roversi, P, Ilyin, V, Carter Jr, C.W.
Deposit date:2002-08-02
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.Mol.Biol., 325, 2003
1M83
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BU of 1m83 by Molmil
Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with ATP in a Closed, Pre-transition State Conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Retailleau, P, Huang, X, Yin, Y, Hu, M, Weinreb, V, Vachette, P, Vonrhein, C, Bricogne, G, Roversi, P, Ilyin, V, Carter Jr, C.W.
Deposit date:2002-07-24
Release date:2002-12-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.Mol.Biol., 325, 2003
1MAU
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BU of 1mau by Molmil
Crystal structure of Tryptophanyl-tRNA Synthetase Complexed with ATP and Tryptophanamide in a Pre-Transition state Conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, GLYCEROL, ...
Authors:Retailleau, P, Huang, X, Yin, Y, Hu, M, Weinreb, V, Vachette, P, Vonrhein, C, Bricogne, G, Roversi, P, Ilyin, V, Carter Jr, C.W.
Deposit date:2002-08-02
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.Mol.Biol., 325, 2003
1MB2
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BU of 1mb2 by Molmil
Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation
Descriptor: TRYPTOPHAN, TRYPTOPHAN-TRNA LIGASE
Authors:Retailleau, P, Huang, X, Yin, Y, Hu, M, Weinreb, V, Vachette, P, Vonrhein, C, Bricogne, G, Roversi, P, Ilyin, V, Carter Jr, C.W.
Deposit date:2002-08-02
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.Mol.Biol., 325, 2003

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