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4X0J
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BU of 4x0j by Molmil
Trypanosoma brucei haptoglobin-haemoglobin receptor
Descriptor: Haptoglobin-hemoglobin receptor
Authors:Lane-Serff, H, MacGregor, P, Lowe, E.D, Carrington, M, Higgins, M.K.
Deposit date:2014-11-21
Release date:2014-12-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor.
Elife, 3, 2014
4X0L
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BU of 4x0l by Molmil
Human haptoglobin-haemoglobin complex
Descriptor: CACODYLATE ION, GLYCEROL, Haptoglobin, ...
Authors:Lane-Serff, H, MacGregor, P, Lowe, E.D, Carrington, M, Higgins, M.K.
Deposit date:2014-11-21
Release date:2014-12-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor.
Elife, 3, 2014
5M4T
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BU of 5m4t by Molmil
C-terminal domain structure of VSG M1.1
Descriptor: Variant surface glycoprotein MITAT 1.1
Authors:Jones, N.G, Mott, H.R, Carrington, M.
Deposit date:2016-10-19
Release date:2017-09-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis for the shielding function of the dynamic trypanosome variant surface glycoprotein coat.
Nat Microbiol, 2, 2017
6XZ6
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BU of 6xz6 by Molmil
Structure of the trypanosome brucei factor H receptor bound to domain D5 of bovine factor H
Descriptor: Complement factor H, GARP domain-containing protein
Authors:Macleod, O.J.S, Carrington, M, Higgins, M.K.
Deposit date:2020-02-02
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.
Nat Commun, 11, 2020
6SOY
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BU of 6soy by Molmil
Trypanosoma brucei transferrin receptor in complex with human transferrin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, subunit of heterodimeric transferrin receptor, ...
Authors:Trevor, C, Carrington, M, Higgins, M.K.
Deposit date:2019-08-30
Release date:2019-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion.
Nat Microbiol, 4, 2019
6SOZ
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BU of 6soz by Molmil
Glycosylated Trypanosoma brucei transferrin receptor in complex with human transferrin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, ...
Authors:Trevor, C, Carrington, M, Higgins, M.K.
Deposit date:2019-08-30
Release date:2019-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion.
Nat Microbiol, 4, 2019
4E40
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BU of 4e40 by Molmil
The haptoglobin-hemoglobin receptor of Trypanosoma congolense
Descriptor: Putative uncharacterized protein
Authors:Higgins, M.K, Tkachenko, O, Brown, A, Reed, J, Carrington, M.
Deposit date:2012-03-11
Release date:2013-01-16
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunity.
Proc.Natl.Acad.Sci.USA, 110, 2013
2JWH
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BU of 2jwh by Molmil
Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein
Descriptor: Variant surface glycoprotein ILTAT 1.24
Authors:Jones, N.G, Nietlispach, D, Sharma, R, Burke, D.F, Eyres, I, Mues, M, Mott, H.R, Carrington, M.
Deposit date:2007-10-12
Release date:2007-11-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein
J.Biol.Chem., 283, 2008
2JWG
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BU of 2jwg by Molmil
Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein
Descriptor: Variant surface glycoprotein ILTAT 1.24
Authors:Jones, N.G, Nietlispach, D, Sharma, R, Burke, D.F, Eyres, I, Mues, M, Mott, H.R, Carrington, M.
Deposit date:2007-10-12
Release date:2007-11-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein
J.Biol.Chem., 283, 2008
1XU6
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BU of 1xu6 by Molmil
Structure of the C-terminal domain from Trypanosoma brucei Variant Surface Glycoprotein MITat1.2
Descriptor: Variant surface glycoprotein MITAT 1.2
Authors:Chattopadhyay, A, Jones, N.G, Nietlispach, D, Nielsen, P.R, Voorheis, H.P, Mott, H.R, Carrington, M.
Deposit date:2004-10-25
Release date:2004-11-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the C-terminal domain from Trypanosoma brucei variant surface glycoprotein MITat1.2
J.Biol.Chem., 280, 2004
7PI6
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BU of 7pi6 by Molmil
Trypanosoma brucei ISG65 bound to human complement C3d
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 65 kDa invariant surface glycoprotein, Complement C3dg fragment, ...
Authors:Cook, A.D, Higgins, M.K.
Deposit date:2021-08-19
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor.
Nat Commun, 13, 2022
2VSG
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BU of 2vsg by Molmil
A Structural Motif in the Variant Surface Glycoproteins of Trypanosoma Brucei
Descriptor: VARIANT SURFACE GLYCOPROTEIN ILTAT 1.24
Authors:Blum, M.L, Down, J.A, Metcalf, P, Freymann, D.M, Wiley, D.C.
Deposit date:1998-11-19
Release date:1998-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A structural motif in the variant surface glycoproteins of Trypanosoma brucei.
Nature, 362, 1993
5LY9
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BU of 5ly9 by Molmil
Structure of MITat 1.1
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Variant surface glycoprotein MITAT 1.1, ...
Authors:Schaefer, C, Bartossek, T, Jones, N, Kuper, J, Kisker, C, Engstler, M.
Deposit date:2016-09-26
Release date:2017-09-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for the shielding function of the dynamic trypanosome variant surface glycoprotein coat.
Nat Microbiol, 2, 2017
8OVB
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BU of 8ovb by Molmil
Human Complement C3b in complex with Trypanosoma brucei ISG65.
Descriptor: Complement C3, Complement C3f fragment, ISG65 G
Authors:Cook, A.D, Higgins, M.K.
Deposit date:2023-04-25
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular mechanism of complement factor C3b inhibition by the trypanosome ISG65 receptor.
To be published
6ELU
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BU of 6elu by Molmil
Structure of Serum Resistance Associated protein from T. b. rhodesiense
Descriptor: G10_3 Light chain, G10_3 heavy chain, Serum resistance associated; VSG protein
Authors:Zoll, S, Higgins, M.K.
Deposit date:2017-09-29
Release date:2018-01-24
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of serum resistance-associated protein and its implications for human African trypanosomiasis.
Nat Microbiol, 3, 2018
1VSG
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BU of 1vsg by Molmil
2.9 ANGSTROMS RESOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF A VARIANT SURFACE GLYCOPROTEIN FROM TRYPANOSOMA BRUCEI
Descriptor: VARIANT SURFACE GLYCOPROTEIN MITAT 1.2, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Freymann, D, Down, J, Wiley, D.C.
Deposit date:1990-10-22
Release date:1992-01-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:2.9 A resolution structure of the N-terminal domain of a variant surface glycoprotein from Trypanosoma brucei.
J.Mol.Biol., 216, 1990
5HU6
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BU of 5hu6 by Molmil
Structure of the T. brucei haptoglobin-haemoglobin receptor bound to human haptolgobin-haemoglobin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Haptoglobin, Haptoglobin-hemoglobin receptor, ...
Authors:Lane-Serff, H, Higgins, M.K.
Deposit date:2016-01-27
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor.
Elife, 3, 2014
5JDO
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BU of 5jdo by Molmil
T. congolense haptoglobin-haemoglobin receptor in complex with haemoglobin
Descriptor: Haptoglobin-haemoglobin receptor, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Lane-Serff, H, Higgins, M.K.
Deposit date:2016-04-17
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor.
Elife, 5, 2016
5VGE
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BU of 5vge by Molmil
Crystal structure of HLA-C*07:02 in complex with RYR peptide
Descriptor: ARG-TYR-ARG-PRO-GLY-THR-VAL-ALA-LEU, Beta-2-microglobulin, ZINC ION, ...
Authors:Mobbs, J.I, Vivian, J.P, Gras, S, Rossjohn, J.
Deposit date:2017-04-11
Release date:2017-06-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and regulatory diversity shape HLA-C protein expression levels.
Nat Commun, 8, 2017
5VGD
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BU of 5vgd by Molmil
Crystal Structure of HLA-C*0501 in complex with SAE
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, Cw-5 alpha chain, ...
Authors:Gras, S, Rossjohn, J.
Deposit date:2017-04-11
Release date:2017-05-31
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural and regulatory diversity shape HLA-C protein expression levels.
Nat Commun, 8, 2017

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