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2M58
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STRUCTURE OF 2'-5' AG1 LARIAT FORMING RIBOZYME IN ITS INACTIVE STATE
Descriptor:RNA (59-MER)
Authors:Carlomagno, T., Amata, I., Codutti, L., Falb, M., Fohrer, J., Simon, B.
Deposit date:2013-02-18
Release date:2013-04-03
Method:SOLUTION NMR
Cite:Structural principles of RNA catalysis in a 2'-5' lariat-forming ribozyme.
J.Am.Chem.Soc., 135, 2013
1OJ5
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CRYSTAL STRUCTURE OF THE NCO-A1 PAS-B DOMAIN BOUND TO THE STAT6 TRANSACTIVATION DOMAIN LXXLL MOTIF
Descriptor:STEROID RECEPTOR COACTIVATOR 1A, SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6, IODIDE ION
Authors:Razeto, A., Ramakrishnan, V., Giller, K., Lakomek, N., Carlomagno, T., Griesinger, C., Lodrini, M., Litterst, C.M., Pftizner, E., Becker, S.
Deposit date:2003-07-02
Release date:2004-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure of the Ncoa-1/Src-1 Pas-B Domain Bound to the Lxxll Motif of the Stat6 Transactivation Domain
J.Mol.Biol., 336, 2004
2KDU
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STRUCTURAL BASIS OF THE MUNC13-1/CA2+-CALMODULIN INTERACTION: A NOVEL 1-26 CALMODULIN BINDING MOTIF WITH A BIPARTITE BINDING MODE
Descriptor:Calmodulin, Protein unc-13 homolog A, CALCIUM ION
Authors:Rodriguez-Castaneda, F.A., Maestre-Martinez, M., Coudevylle, N., Dimova, K., Jahn, O., Junge, H., Becker, S., Brose, N., Carlomagno, T., Griesinger, C.
Deposit date:2009-01-19
Release date:2009-12-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity.
Embo J., 29, 2010
2N0R
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RNA STRUCTURE DETERMINATION BY SOLID-STATE NMR SPECTROSCOPY
Descriptor:RNA (5'-R(*GP*CP*UP*GP*AP*GP*CP*UP*CP*GP*AP*AP*AP*GP*AP*GP*CP*AP*AP*UP*GP*AP*UP*GP*UP*C)-3')
Authors:Marchanka, A., Simon, B., Althoff-Ospelt, G., Carlomagno, T.
Deposit date:2015-03-12
Release date:2015-05-20
Last modified:2015-05-27
Method:SOLID-STATE NMR
Cite:RNA structure determination by solid-state NMR spectroscopy.
Nat Commun, 6, 2015
2N2O
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STRUCTURE OF MURINE TUMOUR NECROSIS FACTOR ALPHA CDE RNA
Descriptor:RNA (5'-R(P*GP*CP*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*UP*U)-3')
Authors:Codutti, L., Leppek, K., Zalesak, J., Windeisen, V., Masiewicz, P., Stoecklin, G., Carlomagno, T.
Deposit date:2015-05-11
Release date:2015-08-05
Last modified:2015-08-26
Method:SOLUTION NMR
Cite:A Distinct, Sequence-Induced Conformation Is Required for Recognition of the Constitutive Decay Element RNA by Roquin.
Structure, 23, 2015
2N2P
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SOLUTION STRUCTURE OF A DOUBLE BASE-PAIR INVERSION MUTANT OF MURINE TUMOUR NECROSIS FACTOR ALPHA CDE-23 RNA
Descriptor:RNA (5'-R(P*GP*CP*AP*UP*GP*UP*UP*UP*AP*GP*UP*GP*UP*CP*UP*AP*AP*AP*CP*GP*GP*UP*U)-3')
Authors:Codutti, L., Leppek, K., Zalesak, J., Windeisen, V., Masiewicz, P., Stoecklin, G., Carlomagno, T.
Deposit date:2015-05-11
Release date:2015-08-05
Last modified:2015-08-26
Method:SOLUTION NMR
Cite:A Distinct, Sequence-Induced Conformation Is Required for Recognition of the Constitutive Decay Element RNA by Roquin.
Structure, 23, 2015
2XEB
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NMR STRUCTURE OF THE PROTEIN-UNBOUND SPLICEOSOMAL U4 SNRNA 5' STEM LOOP
Descriptor:5'-R(P*GP*AP*UP*CP*GP*UP*AP*GP*CP*CP*AP*AP*UP*GP*AP* GP*GP*UP*U)-3', 5'-R(P*GP*CP*CP*GP*AP*GP*GP*CP*GP*CP*GP*AP*UP*C)-3'
Authors:Falb, M., Amata, I., Gabel, F., Simon, B., Carlomagno, T.
Deposit date:2010-05-12
Release date:2010-05-26
Last modified:2018-01-17
Method:SOLUTION NMR
Cite:Structure of the K-turn U4 RNA: a combined NMR and SANS study.
Nucleic Acids Res., 38, 2010
2XFM
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COMPLEX STRUCTURE OF THE MIWI PAZ DOMAIN BOUND TO METHYLATED SINGLE STRANDED RNA
Descriptor:PIWI-LIKE PROTEIN 1, 5'-R(*AP*CP*CP*GP*AP*CP*UP*(OMU)P)-3'
Authors:Simon, B., Kirkpatrick, J.P., Eckhardt, S., Sehr, P., Andrade-Navarro, M.A., Pillai, R.S., Carlomagno, T.
Deposit date:2010-05-27
Release date:2011-01-26
Last modified:2011-10-26
Method:SOLUTION NMR
Cite:Recognition of 2'-O-Methylated 3'-End of Pirna by the Paz Domain of a Piwi Protein.
Structure, 19, 2011
4BD3
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PHF19 LINKS METHYLATED LYSINE 36 OF HISTONE H3 TO REGULATION OF POLYCOMB ACTIVITY
Descriptor:PHD FINGER PROTEIN 19, HISTONE H3
Authors:Lapinaite, A., Simon, B., Carlomagno, T.
Deposit date:2012-10-04
Release date:2012-10-31
Last modified:2012-12-19
Method:SOLUTION NMR
Cite:Phf19 Links Methylated Lys36 of Histone H3 to Regulation of Polycomb Activity
Nat.Struct.Mol.Biol., 19, 2012
4BY9
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THE STRUCTURE OF THE BOX CD ENZYME REVEALS REGULATION OF RRNA METHYLATION
Descriptor:SSR26, NOP5/NOP56 RELATED PROTEIN, 50S RIBOSOMAL PROTEIN L7AE, ...
Authors:Lapinaite, A., Simon, B., Skjaerven, L., Rakwalska-Bange, M., Gabel, F., Carlomagno, T.
Deposit date:2013-07-18
Release date:2013-10-09
Last modified:2016-05-04
Method:SOLUTION NMR
Cite:The Structure of the Box C/D Enzyme Reveals Regulation of RNA Methylation.
Nature, 502, 2013
5A17
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THE STRUCTURE OF THE SOLE ELEMENT OF OSKAR MRNA
Descriptor:OSKAR MRNA
Authors:Simon, B., Masiewicz, P., Ephrussi, A., Carlomagno, T.
Deposit date:2015-04-28
Release date:2015-05-06
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:The Structure of the Sole Element of Oskar Mrna.
RNA, 21, 2015
5A18
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THE STRUCTURE OF THE SOLE ELEMENT OF OSKAR MRNA
Descriptor:OSKAR MRNA
Authors:Simon, B., Masiewicz, P., Ephrussi, A., Carlomagno, T.
Deposit date:2015-04-28
Release date:2015-05-06
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:The Structure of the Sole Element of Oskar Mrna.
RNA, 21, 2015
6F0Y
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RTT109 PEPTIDE BOUND TO ASF1
Descriptor:Histone chaperone ASF1, histone acetyltransferase Rtt109 C-terminus
Authors:Lercher, L., Kirkpatrick, J.P., Carlomagno, T.
Deposit date:2017-11-21
Release date:2017-12-27
Last modified:2018-04-04
Method:SOLUTION NMR
Cite:Structural characterization of the Asf1-Rtt109 interaction and its role in histone acetylation.
Nucleic Acids Res., 46, 2018
2OZB
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STRUCTURE OF A HUMAN PRP31-15.5K-U4 SNRNA COMPLEX
Descriptor:RNA comprising the 5' Stem-Loop RNA of U4snRNA, U4/U6.U5 tri-snRNP 15.5 kDa protein, U4/U6 small nuclear ribonucleoprotein Prp31, ...
Authors:Liu, S., Luehrmann, R., Wahl, M.C.
Deposit date:2007-02-26
Release date:2007-03-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.
Science, 316, 2007
3DND
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CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 5-benzyl-1,3-thiazol-2-amine
Authors:Schiffer, A., Wendt, K.U.
Deposit date:2008-07-02
Release date:2009-06-23
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystallography-independent determination of ligand binding modes
Angew.Chem.Int.Ed.Engl., 47, 2008
3DNE
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CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 3-pyridin-4-yl-1H-indazole
Authors:Schiffer, A., Wendt, K.U.
Deposit date:2008-07-02
Release date:2009-06-23
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallography-independent determination of ligand binding modes
Angew.Chem.Int.Ed.Engl., 47, 2008
4IE9
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BOVINE PKA C-ALPHA IN COMPLEX WITH 3-PYRIDYLMETHYL-5-METHYL-1H-PYRAZOLE-3-CARBOXYLATE
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, pyridin-3-ylmethyl 5-methyl-1H-pyrazole-3-carboxylate, ...
Authors:Dreyer, M.K., Schiffer, A., Lodge, J.
Deposit date:2012-12-13
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Accounting for Conformational Variability in Protein-Ligand Docking with NMR-Guided Rescoring
J.Am.Chem.Soc., 135, 2013
4IJ9
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BOVINE PKA C-ALPHA IN COMPLEX WITH 2-[[5-(4-PYRIDYL)-1H-1,2,4-TRIAZOL-3-YL]SULFANYL]-1-(2-THIOPHENYL)ETHANONE
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 2-[[5-(4-pyridyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-(2-thiophenyl)ethanone
Authors:Dreyer, M.K., Schiffer, A.
Deposit date:2012-12-21
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Accounting for Conformational Variability in Protein-Ligand Docking with NMR-Guided Rescoring
J.Am.Chem.Soc., 135, 2013
5NWX
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INSIGHT INTO THE MOLECULAR RECOGNITION MECHANISM OF THE COACTIVATOR NCOA1 BY STAT6
Descriptor:Nuclear receptor coactivator 1, Signal transducer and activator of transcription 6
Authors:Russo, L., Giller, K., Pfitzner, E., Griesinger, C., Becker, S.
Deposit date:2017-05-08
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6.
Sci Rep, 7, 2017