Author results

3PJZ
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CRYSTAL STRUCTURE OF THE POTASSIUM TRANSPORTER TRKH FROM VIBRIO PARAHAEMOLYTICUS
Descriptor:Potassium uptake protein TrkH, POTASSIUM ION
Authors:Cao, Y., Jin, X., Huang, H., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2010-11-10
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.506 Å)
Cite:Crystal structure of a potassium ion transporter, TrkH.
Nature, 471, 2011
3QNQ
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CRYSTAL STRUCTURE OF THE TRANSPORTER CHBC, THE IIC COMPONENT FROM THE N,N'-DIACETYLCHITOBIOSE-SPECIFIC PHOSPHOTRANSFERASE SYSTEM
Descriptor:PTS system, cellobiose-specific IIC component, DI(N-ACETYL-D-GLUCOSAMINE), ...
Authors:Cao, Y., Jin, X., Huang, H., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2011-02-08
Release date:2011-04-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.295 Å)
Cite:Crystal structure of a phosphorylation-coupled saccharide transporter.
Nature, 473, 2011
4J9U
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CRYSTAL STRUCTURE OF THE TRKH/TRKA POTASSIUM TRANSPORT COMPLEX
Descriptor:Trk system potassium uptake protein TrkH, Potassium uptake protein TrkA, HEXATANTALUM DODECABROMIDE, ...
Authors:Cao, Y., Jin, X., Huang, H., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2013-02-17
Release date:2013-04-03
Last modified:2013-05-01
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Gating of the TrkH ion channel by its associated RCK protein TrkA.
Nature, 496, 2013
1A2F
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PROBING THE STRENGTH AND CHARACTER OF AN ASP-HIS-X HYDROGEN BOND BY INTRODUCING BURIED CHARGES
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Cao, Y., Goodin, D.B., Mcree, D.E.
Deposit date:1998-01-02
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Probing the Strength and Character of an Asp-His-X Hydrogen Bond by Introducing Buried Charges
To be Published
1A2G
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PROBING THE STRENGTH AND CHARACTER OF AN ASP-HIS-X HYDROGEN BOND BY INTRODUCING BURIED CHARGES
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Cao, Y., Goodin, D.B., Mcree, D.E.
Deposit date:1998-01-02
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Probing the Strength and Character of an Asp-His-X Hydrogen Bond by Introducing Buried Charges
To be Published
1CCJ
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CONFORMER SELECTION BY LIGAND BINDING OBSERVED WITH PROTEIN CRYSTALLOGRAPHY
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Cao, Y., Musah, R.A., Wilcox, S.K., Goodin, D.B., Mcree, D.E.
Deposit date:1997-01-22
Release date:1997-07-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Protein conformer selection by ligand binding observed with crystallography.
Protein Sci., 7, 1998
1CCL
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PROBING THE STRENGTH AND CHARACTER OF AN ASP-HIS-X HYDROGEN BOND BY INTRODUCING BURIED CHARGES
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Cao, Y., Goodin, D.B., Mcree, D.E.
Deposit date:1998-01-02
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Probing the Strength and Character of an Asp-His-X Hydrogen Bond by Introducing Buried Charges
To be Published
4EZC
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CRYSTAL STRUCTURE OF THE UT-B UREA TRANSPORTER FROM BOS TAURUS
Descriptor:Urea transporter 1, BETA-D-GLUCOSE, B-OCTYLGLUCOSIDE, ...
Authors:Cao, Y., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2012-05-02
Release date:2012-06-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structure and permeation mechanism of a mammalian urea transporter.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EZD
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CRYSTAL STRUCTURE OF THE UT-B UREA TRANSPORTER FROM BOS TAURUS BOUND TO SELENOUREA
Descriptor:Urea transporter 1, selenourea, BETA-D-GLUCOSE, ...
Authors:Cao, Y., Levin, E.J., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2012-05-02
Release date:2012-06-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and permeation mechanism of a mammalian urea transporter.
Proc.Natl.Acad.Sci.USA, 109, 2012
4J9V
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CRYSTAL STRUCTURE OF THE TRKA GATING RING BOUND TO ATP-GAMMA-S
Descriptor:Potassium uptake protein TrkA, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Huang, H., Levin, E.J., Jin, X., Cao, Y., Zhou, M., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2013-02-17
Release date:2013-04-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.051 Å)
Cite:Gating of the TrkH ion channel by its associated RCK protein TrkA.
Nature, 496, 2013
3EAU
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VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT IN COMPLEX WITH CORTISONE
Descriptor:Voltage-gated potassium channel subunit beta-2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE
Authors:Pan, Y., Weng, J., Kabaleeswaran, V., Li, H., Cao, Y., Bhosle, R.C., Zhou, M.
Deposit date:2008-08-26
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Cortisone dissociates the Shaker family K+ channels from their beta subunits.
Nat.Chem.Biol., 4, 2008
3EB3
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VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT (W121A) IN COMPLEX WITH CORTISONE
Descriptor:Voltage-gated potassium channel subunit beta-2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE
Authors:Pan, Y., Weng, J., Kabaleeswaran, V., Li, H., Cao, Y., Bhosle, R.C., Zhou, M.
Deposit date:2008-08-26
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cortisone dissociates the Shaker family K+ channels from their beta subunits.
Nat.Chem.Biol., 4, 2008
3EB4
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VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT (I211R) IN COMPLEX WITH CORTISONE
Descriptor:Voltage-gated potassium channel subunit beta-2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE
Authors:Pan, Y., Weng, J., Kabaleeswaran, V., Li, H., Cao, Y., Bhosle, R.C., Zhou, M.
Deposit date:2008-08-26
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cortisone dissociates the Shaker family K+ channels from their beta subunits.
Nat.Chem.Biol., 4, 2008
5JDB
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BINDING SPECIFICITY OF P[8] VP8* PROTEINS OF ROTAVIRUS VACCINE STRAINS WITH HISTO-BLOOD GROUP ANTIGENS
Descriptor:Outer capsid protein VP4
Authors:Sun, X., Guo, N., Li, D., Zhou, Y., Jin, M., Xie, G., Pang, L., Zhang, Q., Cao, Y., Duan, Z.
Deposit date:2016-04-16
Release date:2016-07-13
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens.
Virology, 495, 2016
6JFW
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CRYSTAL STRUCTURE OF PA0833 PERIPLASMIC DOMAIN FROM PSEUDOMONAS AERUGINOSA REVEALS AN UNEXPECTED ENLARGED PEPTIDOGLYCAN BINDING POCKET
Descriptor:PA0833-PD protein
Authors:Lin, X., Ye, F., Lin, S., Yang, F.L., Chen, Z.M., Cao, Y., Chen, Z.J., Gu, J., Lu, G.W.
Deposit date:2019-02-12
Release date:2019-03-20
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal structure of PA0833 periplasmic domain from Pseudomonas aeruginosa reveals an unexpected enlarged peptidoglycan binding pocket.
Biochem. Biophys. Res. Commun., 2019
1CCI
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HOW FLEXIBLE ARE PROTEINS? TRAPPING OF A FLEXIBLE LOOP
Descriptor:CYTOCHROME C PEROXIDASE, 2,3-DIMETHYLIMIDAZOLIUM ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Cao, Y., Musah, R.A., Wilcox, S.K., Goodin, D.B., Mcree, D.E.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity.
Nat.Struct.Biol., 3, 1996
1CCK
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ALTERING SUBSTRATE SPECIFICITY OF CYTOCHROME C PEROXIDASE TOWARDS A SMALL MOLECULAR SUBSTRATE PEROXIDASE BY SUBSTITUTING TYROSINE FOR PHE 202
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Cao, Y., Musah, R.A., Wilcox, S.K., Goodin, D.B., Mcree, D.E.
Deposit date:1998-01-02
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of recombinant pea cytosolic ascorbate peroxidase.
Biochemistry, 34, 1995
6D1W
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HUMAN PKD2 F604P MUTANT
Descriptor:Polycystin-2, N-ACETYL-D-GLUCOSAMINE
Authors:Zheng, W., Yang, X., Bulkley, D., Chen, X.Z., Cao, E.
Deposit date:2018-04-12
Release date:2018-06-27
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.
Nat Commun, 9, 2018
6DJC
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CRYSTAL STRUCTURE OF HUMAN BROMODOMAIN-CONTAINING PROTEIN 4 (BRD4) BROMODOMAIN WITH MS645
Descriptor:Bromodomain-containing protein 4, N,N'-(decane-1,10-diyl)bis{2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetamide}, 1,2-ETHANEDIOL
Authors:Ren, C., Zhou, M.M.
Deposit date:2018-05-25
Release date:2018-07-25
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DNE
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CRYSTAL STRUCTURE OF HUMAN BROMODOMAIN-CONTAINING PROTEIN 4 (BRD4) BROMODOMAIN WITH MS660
Descriptor:Bromodomain-containing protein 4, N,N'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis{2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetamide}
Authors:Ren, C., Zhou, M.M.
Deposit date:2018-06-06
Release date:2018-07-18
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (2.958 Å)
Cite:Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3JUG
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CRYSTAL STRUCTURE OF ENDO-BETA-1,4-MANNANASE FROM THE ALKALIPHILIC BACILLUS SP. N16-5
Descriptor:Beta-mannanase, SULFATE ION
Authors:Zhao, Y., Zhang, Y., Xue, Y.
Deposit date:2009-09-15
Release date:2010-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure Analysis of Alkaline beta-mannanase from Alkaliphilic Bacillus sp. N16-5 Implications for Adaptation to Alkaline Conditions
To be Published
3RZ2
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CRYSTAL OF PRL-1 COMPLEXED WITH PEPTIDE
Descriptor:Protein tyrosine phosphatase type IVA 1, Prl-1 (PTP4A1)
Authors:Zhang, Z.-Y., Liu, D., Bai, Y.
Deposit date:2011-05-11
Release date:2011-10-26
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.
J.Biol.Chem., 286, 2011
3PDV
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STRUCTURE OF THE PDLIM2 PDZ DOMAIN IN COMPLEX WITH THE C-TERMINAL 6-PEPTIDE EXTENSION OF NS1
Descriptor:PDZ and LIM domain protein 2, C-teminal peptide from Nonstructural protein 1, SODIUM ION
Authors:Li, X.
Deposit date:2010-10-25
Release date:2011-09-07
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1
Plos One, 6, 2011
5Z2C
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CRYSTAL STRUCTURE OF ALPK-1 N-TERMINAL DOMAIN IN COMPLEX WITH ADP-HEPTOSE
Descriptor:Alpha-protein kinase 1, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4S,5S,6R)-6-[(1S)-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate
Authors:Ding, J., She, Y., Shao, F.
Deposit date:2018-01-02
Release date:2018-08-22
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose.
Nature, 561, 2018
6AF0
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STRUCTURE OF CTR9, PAF1 AND CDC73 TERNARY COMPLEX FROM MYCELIOPHTHORA THERMOPHILA
Descriptor:Ctr9 protein, Paf1 protein, Cdc73 protein
Authors:Wang, Z., Deng, P., Zhou, Y.
Deposit date:2018-08-07
Release date:2018-09-19
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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