Author results

2IF7
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CRYSTAL STRUCTURE OF NTB-A
Descriptor:SLAM family member 6, CALCIUM ION, CHLORIDE ION
Authors:Cao, E., Ramagopal, U.A., Fedorov, A.A., Fedorov, E.V., Nathenson, S.G., Almo, S.C.
Deposit date:2006-09-20
Release date:2006-10-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:NTB-A Receptor Crystal Structure: Insights into Homophilic Interactions in the Signaling Lymphocytic Activation Molecule Receptor Family.
Immunity, 25, 2006
2OYP
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T CELL IMMUNOGLOBULIN MUCIN-3 CRYSTAL STRUCTURE REVEALED A GALECTIN-9-INDEPENDENT BINDING SURFACE
Descriptor:Hepatitis A virus cellular receptor 2, SULFATE ION
Authors:Cao, E., Ramagopal, U.A., Fedorov, A.A., Fedorov, E.V., Nathenson, S.G., Almo, S.C.
Deposit date:2007-02-22
Release date:2007-04-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface
Immunity, 26, 2007
3J5Q
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STRUCTURE OF TRPV1 ION CHANNEL IN COMPLEX WITH DKTX AND RTX DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1, Double-knot toxin
Authors:Liao, M., Cao, E., Julius, D., Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
3J5R
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RECONSTRUCTION OF TRPV1 ION CHANNEL IN COMPLEX WITH CAPSAICIN BY SINGLE PARTICLE CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1
Authors:Liao, M., Cao, E., Julius, D., Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
6D1W
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HUMAN PKD2 F604P MUTANT
Descriptor:Polycystin-2, N-ACETYL-D-GLUCOSAMINE
Authors:Zheng, W., Yang, X., Bulkley, D., Chen, X.Z., Cao, E.
Deposit date:2018-04-12
Release date:2018-06-27
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.
Nat Commun, 9, 2018
3BOV
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CRYSTAL STRUCTURE OF THE RECEPTOR BINDING DOMAIN OF MOUSE PD-L2
Descriptor:Programmed cell death 1 ligand 2, SODIUM ION, FORMIC ACID
Authors:Lazar-Molnar, E., Ramagopal, U., Cao, E., Toro, R., Nathenson, S.G., Almo, S.C.
Deposit date:2007-12-17
Release date:2008-07-15
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.USA, 105, 2008
3BP5
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CRYSTAL STRUCTURE OF THE MOUSE PD-1 AND PD-L2 COMPLEX
Descriptor:Programmed cell death protein 1, Programmed cell death 1 ligand 2, GLYCEROL
Authors:Yan, Q., Lazar-Molnar, E., Cao, E., Ramagopal, U.A., Toro, R., Nathenson, S.G., Almo, S.C.
Deposit date:2007-12-18
Release date:2008-07-15
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BP6
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CRYSTAL STRUCTURE OF THE MOUSE PD-1 MUTANT AND PD-L2 COMPLEX
Descriptor:Programmed cell death protein 1, Programmed cell death 1 ligand 2, GLYCEROL
Authors:Yan, Q., Lazar-Molnar, E., Cao, E., Ramagopal, U.A., Toro, R., Nathenson, S.G., Almo, S.C.
Deposit date:2007-12-18
Release date:2009-02-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the mouse PD-1 A99L and PD-L2 complex
To be published
3RNK
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN MOUSE PD-1 MUTANT AND PD-L2 IGV DOMAIN
Descriptor:Programmed cell death protein 1, Programmed cell death 1 ligand 2
Authors:Lazar-Molnar, E., Ramagopal, U.A., Cao, E., Nathenson, S.G., Almo, S.C.
Deposit date:2011-04-22
Release date:2011-06-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of the complex between mouse PD-1 mutant and PD-L2 IgV domain
To be Published
3SBW
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE EXTRACELLULAR DOMAINS OF MOUSE PD-1 MUTANT AND HUMAN PD-L1
Descriptor:Programmed cell death protein 1, Programmed cell death 1 ligand 1
Authors:Lazar-Molnar, E., Ramagopal, U.A., Cao, E., Nathenson, S.G., Almo, S.C.
Deposit date:2011-06-06
Release date:2011-07-13
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1
To be published
2PKD
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CRYSTAL STRUCTURE OF CD84: INSITE INTO SLAM FAMILY FUNCTION
Descriptor:SLAM family member 5, CHLORIDE ION
Authors:Yan, Q., Malashkevich, V.N., Fedorov, A., Cao, E., Lary, J.W., Cole, J.L., Nathenson, S.G., Almo, S.C.
Deposit date:2007-04-17
Release date:2007-06-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:Structure of CD84 provides insight into SLAM family function.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1NPU
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MURINE PD-1
Descriptor:Programmed cell death protein 1
Authors:Zhang, X., Schwartz, J.-C.D., Guo, X., Cao, E., Chen, L., Zhang, Z.-Y., Nathenson, S.G., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2003-01-20
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the costimulatory receptor programmed death-1.
Immunity, 20, 2004
3J5P
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STRUCTURE OF TRPV1 ION CHANNEL DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1
Authors:Liao, M., Cao, E., Julius, D., Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.275 Å)
Cite:Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
Nature, 504, 2013
5IRX
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STRUCTURE OF TRPV1 IN COMPLEX WITH DKTX AND RTX, DETERMINED IN LIPID NANODISC
Descriptor:Transient receptor potential cation channel subfamily V member 1, Tau-theraphotoxin-Hs1a, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ...
Authors:Gao, Y., Cao, E., Julius, D., Cheng, Y.
Deposit date:2016-03-14
Release date:2016-05-25
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
5IRZ
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STRUCTURE OF TRPV1 DETERMINED IN LIPID NANODISC
Descriptor:Transient receptor potential cation channel subfamily V member 1, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(pentanoyloxy)propan-2-yl decanoate, ...
Authors:Gao, Y., Cao, E., Julius, D., Cheng, Y.
Deposit date:2016-03-15
Release date:2016-05-25
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
5IS0
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STRUCTURE OF TRPV1 IN COMPLEX WITH CAPSAZEPINE, DETERMINED IN LIPID NANODISC
Descriptor:Transient receptor potential cation channel subfamily V member 1, capsazepine
Authors:Gao, Y., Cao, E., Julius, D., Cheng, Y.
Deposit date:2016-03-15
Release date:2016-05-25
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
5T4D
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CRYO-EM STRUCTURE OF POLYCYSTIC KIDNEY DISEASE PROTEIN 2 (PKD2), RESIDUES 198-703
Descriptor:hPKD:198-703, Polycystin-2, N-ACETYL-D-GLUCOSAMINE
Authors:Shen, P.S., Yang, X., DeCaen, P.G., Liu, X., Bulkley, D., Clapham, D.E., Cao, E.
Deposit date:2016-08-29
Release date:2016-11-02
Last modified:2017-11-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs.
Cell, 167, 2016
3J9J
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STRUCTURE OF THE CAPSAICIN RECEPTOR, TRPV1, DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1
Authors:Wang, R.Y.-R., Barad, B.A., Fraser, J.S., DiMaio, F.
Deposit date:2015-02-02
Release date:2015-09-02
Last modified:2015-10-14
Method:ELECTRON MICROSCOPY (3.275 Å)
Cite:EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.
Nat.Methods, 12, 2015
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