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2A79
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MAMMALIAN SHAKER KV1.2 POTASSIUM CHANNEL- BETA SUBUNIT COMPLEX
Descriptor:Voltage-gated potassium channel beta-2 subunit, Potassium voltage-gated channel subfamily A member 2, poly-unknown chain, ...
Authors:Long, S.B., Campbell, E.B., MacKinnon, R.
Deposit date:2005-07-05
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a mammalian voltage-dependent Shaker family K+ channel.
Science, 309, 2005
2R9R
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SHAKER FAMILY VOLTAGE DEPENDENT POTASSIUM CHANNEL (KV1.2-KV2.1 PADDLE CHIMERA CHANNEL) IN ASSOCIATION WITH BETA SUBUNIT
Descriptor:Voltage-gated potassium channel subunit beta-2, Paddle chimera voltage gated potassium channel Kv1.2-Kv2.1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Long, S.B., Tao, X., Campbell, E.B., Mackinnon, R.
Deposit date:2007-09-13
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment.
Nature, 450, 2007
1KPK
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CRYSTAL STRUCTURE OF THE CLC CHLORIDE CHANNEL FROM E. COLI
Descriptor:putative channel transporter
Authors:Dutzler, R., Campbell, E.B., Cadene, M., Chait, B.T., MacKinnon, R.
Deposit date:2001-12-31
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
Nature, 415, 2002
1KPL
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CRYSTAL STRUCTURE OF THE CLC CHLORIDE CHANNEL FROM S. TYPHIMURIUM
Descriptor:putative ClC family, chlorine transport protein, CHLORIDE ION, ...
Authors:Dutzler, R., Campbell, E.B., Cadene, M., Chait, B.T., MacKinnon, R.
Deposit date:2001-12-31
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
Nature, 415, 2002
1OTS
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STRUCTURE OF THE ESCHERICHIA COLI CLC CHLORIDE CHANNEL AND FAB COMPLEX
Descriptor:Voltage-gated ClC-type chloride channel eriC, Fab fragment (heavy chain), Fab fragment (light chain), ...
Authors:Dutzler, R., Campbell, E.B., MacKinnon, R.
Deposit date:2003-03-22
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
1OTT
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STRUCTURE OF THE ESCHERICHIA COLI CLC CHLORIDE CHANNEL E148A MUTANT AND FAB COMPLEX
Descriptor:Voltage-gated ClC-type chloride channel eriC, Fab fragment (Heavy chain), Fab fragment (Light chain), ...
Authors:Dutzler, R., Campbell, E.B., MacKinnon, R.
Deposit date:2003-03-23
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
1OTU
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STRUCTURE OF THE ESCHERICHIA COLI CLC CHLORIDE CHANNEL E148Q MUTANT AND FAB COMPLEX
Descriptor:Voltage-gated ClC-type chloride channel eriC, Fab fragment (Heavy chain), Fab fragment (Light chain), ...
Authors:Dutzler, R., Campbell, E.B., MacKinnon, R.
Deposit date:2003-03-23
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
3LUT
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A STRUCTURAL MODEL FOR THE FULL-LENGTH SHAKER POTASSIUM CHANNEL KV1.2
Descriptor:Voltage-gated potassium channel subunit beta-2, Potassium voltage-gated channel subfamily A member 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Chen, X., Ni, F., Wang, Q., Ma, J.
Deposit date:2010-02-18
Release date:2010-06-23
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement.
Proc.Natl.Acad.Sci.USA, 107, 2010
3ORG
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CRYSTAL STRUCTURE OF A EUKARYOTIC CLC TRANSPORTER
Descriptor:CmCLC, CHLORIDE ION
Authors:Feng, L., MacKinnon, R.
Deposit date:2010-09-07
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle.
Science, 330, 2010
4FG6
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STRUCTURE OF ECCLC E148A MUTANT IN GLUTAMATE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab fragment (Heavy chain), Fab fragment (Light chain)
Authors:Feng, L., MacKinnon, R.
Deposit date:2012-06-04
Release date:2012-07-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.019 Å)
Cite:Molecular mechanism of proton transport in CLC Cl-/H+ exchange transporters.
Proc.Natl.Acad.Sci.USA, 109, 2012
4I9W
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HUMAN TWO PORE DOMAIN K+ CHANNEL TRAAK (K2P4.1) - FAB COMPLEX STRUCTURE
Descriptor:Potassium channel subfamily K member 4, ANTIBODY FAB FRAGMENT LIGHT CHAIN, ANTIBODY FAB FRAGMENT HEAVY CHAIN, ...
Authors:Brohawn, S.G., Mackinnon, R.
Deposit date:2012-12-05
Release date:2013-01-23
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel.
Proc.Natl.Acad.Sci.USA, 110, 2013
4WFE
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HUMAN TRAAK K+ CHANNEL IN A K+ BOUND CONDUCTIVE CONFORMATION
Descriptor:Potassium channel subfamily K member 4, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ...
Authors:Brohawn, S.G., MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFF
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HUMAN TRAAK K+ CHANNEL IN A K+ BOUND NONCONDUCTIVE CONFORMATION
Descriptor:Potassium channel subfamily K member 4, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ...
Authors:Brohawn, S.G., MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFG
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HUMAN TRAAK K+ CHANNEL IN A TL+ BOUND CONDUCTIVE CONFORMATION
Descriptor:Potassium channel subfamily K member 4, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ...
Authors:Brohawn, S.G., MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFH
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HUMAN TRAAK K+ CHANNEL IN A TL+ BOUND NONCONDUCTIVE CONFORMATION
Descriptor:Potassium channel subfamily K member 4, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ...
Authors:Brohawn, S.G., MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
5TQQ
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF A BOVINE CLC-K CHLORIDE CHANNEL, MAIN (CLASS 1) CONFORMATION
Descriptor:Chloride channel protein, Monoclonal antibody, Fab fragment, ...
Authors:Park, E., MacKinnon, R.
Deposit date:2016-10-24
Release date:2017-01-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structure of a CLC chloride ion channel by cryo-electron microscopy.
Nature, 541, 2017
5TR1
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF A BOVINE CLC-K CHLORIDE CHANNEL, ALTERNATE (CLASS 2) CONFORMATION
Descriptor:Chloride channel protein, Monoclonal antibody, Fab fragment, ...
Authors:Park, E., MacKinnon, R.
Deposit date:2016-10-25
Release date:2017-01-11
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structure of a CLC chloride ion channel by cryo-electron microscopy.
Nature, 541, 2017
1BLA
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BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Powers, R., Seddon, A.P., Bohlen, P., Moy, F.J.
Deposit date:1996-05-20
Release date:1996-11-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996
1BLD
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BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Powers, R., Seddon, A.P., Bohlen, P., Moy, F.J.
Deposit date:1996-05-20
Release date:1996-11-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996