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2MOR
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BU of 2mor by Molmil
A tensor-free method for the structural and dynamical refinement of proteins using residual dipolar couplings
Descriptor: Ubiquitin
Authors:Camilloni, C, Vendruscolo, M.
Deposit date:2014-04-29
Release date:2014-06-25
Last modified:2015-02-04
Method:SOLUTION NMR
Cite:A Tensor-Free Method for the Structural and Dynamical Refinement of Proteins using Residual Dipolar Couplings.
J.Phys.Chem.B, 119, 2015
6Y2K
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BU of 6y2k by Molmil
Crystal structure of beta-galactosidase from the psychrophilic Marinomonas ef1
Descriptor: CHLORIDE ION, GLYCEROL, beta-galactosidase
Authors:Mangiagalli, M, Lapi, M, Maione, S, Orlando, M, Brocca, S, Pesce, A, Barbiroli, A, Pucciarelli, S, Camilloni, C, Lotti, M.
Deposit date:2020-02-16
Release date:2020-05-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The co-existence of cold activity and thermal stability in an Antarctic GH42 beta-galactosidase relies on its hexameric quaternary arrangement.
Febs J., 288, 2021
6HUD
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BU of 6hud by Molmil
Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient.
Descriptor: Monoclonal immunoglobulin light chains (LC)
Authors:Paissoni, C, Camilloni, C.
Deposit date:2018-10-06
Release date:2019-03-27
Last modified:2019-04-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.
Nat Commun, 10, 2019
6G4A
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BU of 6g4a by Molmil
FLN5 (full length)
Descriptor: Gelation factor
Authors:Waudby, C.A, Wlodarski, T, Karyadi, M.-E, Cassaignau, A.M.E, Chan, S.H.S, Wentink, A.S, Schmidt-Engler, J.M, Camilloni, C, Vendruscolo, M, Cabrita, L.D, Christodoulou, J.
Deposit date:2018-03-27
Release date:2019-04-10
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Mapping energy landscapes of a growing filamin domain reveals an intermediate associated with proline isomerization during biosynthesis
To Be Published
6S6X
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BU of 6s6x by Molmil
Structure of Azospirillum brasilense Glutamate Synthase in a6b6 oligomeric state.
Descriptor: FE3-S4 CLUSTER, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Chaves-Sanjuan, A, Camilloni, C, Bolognesi, M.
Deposit date:2019-07-03
Release date:2019-09-11
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM Structures of Azospirillum brasilense Glutamate Synthase in Its Oligomeric Assemblies.
J.Mol.Biol., 431, 2019
2MEZ
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BU of 2mez by Molmil
Flexible anchoring of archaeal MBF1 on ribosomes suggests role as recruitment factor
Descriptor: Multiprotein Bridging Factor (MBP-like)
Authors:Launay, H, Blombarch, F, Camilloni, C, Vendruscolo, M, van des Oost, J, Christodoulou, J.
Deposit date:2013-10-03
Release date:2014-06-25
Last modified:2014-08-20
Method:SOLUTION NMR
Cite:Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain.
Biochem.J., 462, 2014
2N1T
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BU of 2n1t by Molmil
Dynamic binding mode of a synaptotagmin-1-SNARE complex in solution
Descriptor: Synaptosomal-associated protein 25, Synaptotagmin-1, Syntaxin-1A, ...
Authors:Brewer, K, Bacaj, T, Cavalli, A, Camilloni, C, Swarbrick, J, Liu, J, Zhou, A, Zhou, P, Barlow, N, Xu, J, Seven, A, Prinslow, E, Voleti, R, Haussinger, D, Bonvin, A, Tomchick, D, Vendruscolo, M, Graham, B, Sudhof, T, Rizo, J.
Deposit date:2015-04-21
Release date:2015-06-03
Last modified:2021-08-18
Method:SOLUTION NMR
Cite:Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution.
Nat.Struct.Mol.Biol., 22, 2015
2N62
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BU of 2n62 by Molmil
ddFLN5+110
Descriptor: gelation factor, secretion monitor chimera
Authors:Cabrita, L.D, Cassaignau, A.M.E, Launay, H.M.M, Waudby, C.A, Camilloni, C, Robertson, A.L, Wang, X, Wlodarski, T, Wentink, A.S, Vendruscolo, M, Dobson, C.M, Christodoulou, J.
Deposit date:2015-08-10
Release date:2016-03-02
Last modified:2016-04-20
Method:SOLUTION NMR
Cite:A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding.
Nat.Struct.Mol.Biol., 23, 2016
5CKA
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BU of 5cka by Molmil
Human beta-2 microglobulin double mutant W60G-N83V
Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-15
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CKG
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BU of 5ckg by Molmil
Human beta-2 microglobulin mutant V85E
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-15
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CFH
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BU of 5cfh by Molmil
human beta-2 microglobulin double mutant W60G-Y63W
Descriptor: Beta-2-microglobulin
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-08
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
6I8C
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BU of 6i8c by Molmil
Crystal structure of the murine beta-2-microglobulin.
Descriptor: Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:Achour, A, Sandalova, T, Ricagno, S, Sun, R.
Deposit date:2018-11-20
Release date:2019-10-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity.
Febs J., 287, 2020
7AH8
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BU of 7ah8 by Molmil
NF-Y bound to suramin inhibitor
Descriptor: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, CITRATE ANION, GLYCEROL, ...
Authors:Nardone, V, Chaves-Sanjuan, A, Lapi, M, Nardini, M.
Deposit date:2020-09-24
Release date:2021-08-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.70001364 Å)
Cite:Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin.
Cells, 9, 2020
4RMW
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BU of 4rmw by Molmil
Crystal structure of the D76A Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
4RMU
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BU of 4rmu by Molmil
Crystal structure of the D76E Beta-2 Microglobulin mutant
Descriptor: Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
4RMV
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BU of 4rmv by Molmil
Crystal structure of the D76H Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.463 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
7ZCF
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BU of 7zcf by Molmil
SARS-CoV-2 Spike RBD in complex with the single chain fragment scFv76 (Focused Refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, scFv76 single chain fragment
Authors:Chaves-Sanjuan, A, Bolognesi, M.
Deposit date:2022-03-28
Release date:2022-10-12
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery.
Mol.Ther., 31, 2022
7ZCE
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BU of 7zce by Molmil
SARS-CoV-2 Spike protein in complex with the single chain fragment scFv76
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Chaves-Sanjuan, A, Bolognesi, M.
Deposit date:2022-03-28
Release date:2022-10-12
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery.
Mol.Ther., 31, 2022
7P0T
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BU of 7p0t by Molmil
CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 PEPTIDE with D-AMINOACID
Descriptor: Beta-2-microglobulin, CHLORIDE ION, Derived peptide gp33-41 from LCMV, ...
Authors:Broggini, L, Ricagno, S.
Deposit date:2021-06-30
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics.
Acs Omega, 7, 2022
7P0A
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BU of 7p0a by Molmil
CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 PEPTIDE with D-AMINOACID (p3P6f)
Descriptor: Beta-2-microglobulin, CHLORIDE ION, H-2 class I histocompatibility antigen, ...
Authors:Broggini, L, Ricagno, S.
Deposit date:2021-06-29
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.429 Å)
Cite:l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics.
Acs Omega, 7, 2022
5J0M
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BU of 5j0m by Molmil
Ground state sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat
Descriptor: Apical region (29-mer) of the HIV-1 TAR RNA element, Cyclic peptide mimetic of HIV-1 Tat
Authors:Borkar, A.N, Bardaro Jr, M.F, Varani, G, Vendruscolo, M.
Deposit date:2016-03-28
Release date:2016-06-08
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J1O
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BU of 5j1o by Molmil
Excited state (Bound-like) sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat
Descriptor: Apical region (29mer) of the HIV-1 TAR element, Cyclic peptide mimetic of Tat
Authors:Borkar, A.N, Bardaro, M.F, Varani, G, Vendruscolo, M.
Deposit date:2016-03-29
Release date:2016-06-08
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J2W
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BU of 5j2w by Molmil
Intermediate state lying on the pathway of release of Tat from HIV-1 TAR.
Descriptor: Apical region (29mer) of the HIV-1 TAR RNA element, Cyclic peptide mimetic of HIV-1 Tat
Authors:Borkar, A.N, Bardaro Jr, M.F, Varani, G, Vendruscolo, M.
Deposit date:2016-03-30
Release date:2016-06-08
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
5CSG
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BU of 5csg by Molmil
The crystal structure of beta2-microglobulin R97Q mutant
Descriptor: ACETATE ION, Beta-2-microglobulin
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
5CSB
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BU of 5csb by Molmil
The crystal structure of beta2-microglobulin D76N mutant at room temperature
Descriptor: Beta-2-microglobulin
Authors:de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.719 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018

 

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