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6SCT
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CRYO-EM STRUCTURE OF THE CONSENSUS TRISKELION HUB OF THE CLATHRIN COAT COMPLEX
Descriptor:Clathrin heavy chain, Clathrin light chain
Authors:Morris, K.L., Cameron, A.D., Sessions, R., Smith, C.J.
Deposit date:2019-07-25
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.69 Å)
Cite:Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly.
Nat.Struct.Mol.Biol., 26, 2019
6SBZ
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CRYO-EM STRUCTURE OF THE CONSENSUS TRISKELION HUB OF THE CLATHRIN COAT COMPLEX
Descriptor:Clathrin heavy chain, Clathrin light chain
Authors:Morris, K.L., Cameron, A.D., Sessions, R., Smith, C.J.
Deposit date:2019-07-22
Release date:2019-10-16
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.69 Å)
Cite:Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly.
Nat.Struct.Mol.Biol., 26, 2019
6R1B
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CRYSTAL STRUCTURE OF UGPB FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH GLYCEROPHOSPHOCHOLINE
Descriptor:Putative Sn-glycerol-3-phosphate-binding lipoprotein UgpB, 2-(((R)-2,3-DIHYDROXYPROPYL)PHOSPHORYLOXY)-N,N,N-TRIMETHYLETHANAMINIUM, MAGNESIUM ION, ...
Authors:Fenn, J., Nepravishta, R., Guy, C.S., Harrison, J., Angulo, J., Cameron, A.D., Fullam, E.
Deposit date:2019-03-14
Release date:2019-09-04
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (2.270002 Å)
Cite:Structural Basis of Glycerophosphodiester Recognition by theMycobacterium tuberculosisSubstrate-Binding Protein UgpB.
Acs Chem.Biol., 14, 2019
6H7B
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STRUCTURE OF LEISHMANIA PABP1 (DOMAIN J) COMPLEXED WITH A PEPTIDE CONTAINING THE PAM2 MOTIF OF EIF4E4.
Descriptor:Polyadenylate-binding protein, HIS-HIS-MET-ASN-PRO-ASN-ALA-THR-GLU-PHE-MET-PRO
Authors:Cameron, A.D., Firczuk, H., dos Santos Rodrigues, F.H., McCarthy, J.E.G.
Deposit date:2018-07-31
Release date:2018-12-12
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The Leishmania PABP1-eIF4E4 interface: a novel 5'-3' interaction architecture for trans-spliced mRNAs.
Nucleic Acids Res., 47, 2019
6H7A
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STRUCTURE OF LEISHMANIA PABP1 (DOMAIN J).
Descriptor:PABP1 domain J
Authors:Cameron, A.D., Firczuk, H., dos Santos Rodrigues, F.H., McCarthy, J.E.G.
Deposit date:2018-07-31
Release date:2018-12-12
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The Leishmania PABP1-eIF4E4 interface: a novel 5'-3' interaction architecture for trans-spliced mRNAs.
Nucleic Acids Res., 47, 2019
6FV4
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THE STRUCTURE OF N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE DEACETYLASE D267A MUTANT FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE
Descriptor:N-acetylglucosamine-6-phosphate deacetylase, ZINC ION, N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE, ...
Authors:Ahangar, M.S., Furze, C.M., Guy, C.S., Cooper, C., Maskew, K.S., Graham, B., Cameron, A.D., Fullam, E.
Deposit date:2018-03-01
Release date:2018-05-16
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.974 Å)
Cite:Structural and functional determination of homologs of theMycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA).
J. Biol. Chem., 293, 2018
6FV3
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CRYSTAL STRUCTURE OF N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE DEACETYLASE FROM MYCOBACTERIUM SMEGMATIS.
Descriptor:N-acetylglucosamine-6-phosphate deacetylase, ZINC ION
Authors:Ahangar, M.S., Furze, C.M., Guy, C.S., Cooper, C., Maskew, K.S., Graham, B., Cameron, A.D., Fullam, E.
Deposit date:2018-02-28
Release date:2018-05-16
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structural and functional determination of homologs of theMycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA).
J. Biol. Chem., 293, 2018
5I6C
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THE STRUCTURE OF THE EUKARYOTIC PURINE/H+ SYMPORTER, UAPA, IN COMPLEX WITH XANTHINE
Descriptor:Uric acid-xanthine permease, XANTHINE, DODECYL-BETA-D-MALTOSIDE
Authors:Alguel, Y., Amillis, S., Leung, J., Lambrinidis, G., Capaldi, S., Scull, N.J., Craven, G., Iwata, S., Armstrong, A., Mikros, E., Diallinas, G., Cameron, A.D., Byrne, B.
Deposit date:2016-02-16
Release date:2016-04-27
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structure of eukaryotic purine/H(+) symporter UapA suggests a role for homodimerization in transport activity.
Nat Commun, 7, 2016
5BZ3
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CRYSTAL STRUCTURE OF SODIUM PROTON ANTIPORTER NAPA IN OUTWARD-FACING CONFORMATION.
Descriptor:Na(+)/H(+) antiporter, (2R)-2,3-DIHYDROXYPROPYL (7Z)-TETRADEC-7-ENOATE
Authors:Coincon, M., Uzdavinys, P., Emmanuel, N., Cameron, A., Drew, D.
Deposit date:2015-06-11
Release date:2016-01-20
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters.
Nat.Struct.Mol.Biol., 23, 2016
5BZ2
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CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION
Descriptor:Na(+)/H(+) antiporter
Authors:Coincon, M., Uzdavinys, P., Cameron, A., Drew, D.
Deposit date:2015-06-11
Release date:2016-01-20
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters.
Nat.Struct.Mol.Biol., 23, 2016
4YZF
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CRYSTAL STRUCTURE OF THE ANION EXCHANGER DOMAIN OF HUMAN ERYTHROCYTE BAND 3
Descriptor:Band 3 anion transport protein, FAB fragment of Immunoglobulin (IgG) molecule, 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}
Authors:Alguel, Y., Arakawa, T., Yugiri, T.K., Iwanari, H., Hatae, H., Iwata, M., Abe, Y., Hino, T., Suno, C.I., Kuma, H., Kang, D., Murata, T., Hamakubo, T., Cameron, A.D., Kobayashi, T., Hamasaki, N., Iwata, S.
Deposit date:2015-03-25
Release date:2015-11-04
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the anion exchanger domain of human erythrocyte band 3.
Science, 350, 2015
4GAV
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STRUCTURE OF THE NDI1 PROTEIN FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH QUINONE
Descriptor:Rotenone-insensitive NADH-ubiquinone oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, UBIQUINONE-2
Authors:Iwata, M., Lee, Y., Yamashita, T., Yagi, T., Iwata, S., Cameron, A.D., Maher, M.J.
Deposit date:2012-07-25
Release date:2012-09-05
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GAP
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STRUCTURE OF THE NDI1 PROTEIN FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH NAD+
Descriptor:Rotenone-insensitive NADH-ubiquinone oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Iwata, M., Lee, Y., Yamashita, T., Yagi, T., Iwata, S., Cameron, A.D., Maher, M.J.
Deposit date:2012-07-25
Release date:2012-09-05
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4G9K
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STRUCTURE OF THE NDI1 PROTEIN FROM SACCHAROMYCES CEREVISIAE
Descriptor:Rotenone-insensitive NADH-ubiquinone oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Iwata, M., Lee, Y., Yamashita, T., Yagi, T., Iwata, S., Cameron, A.D., Maher, M.J.
Deposit date:2012-07-24
Release date:2012-09-05
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4D1D
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER WITH THE INHIBITOR 5-(2-NAPHTHYLMETHYL)-L-HYDANTOIN.
Descriptor:HYDANTOIN TRANSPORT PROTEIN, 5-(2-NAPHTHYLMETHYL)-L-HYDANTOIN, 5-(2-NAPHTHYLMETHYL)-D-HYDANTOIN, ...
Authors:Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1C
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH BROMOVINYLHYDANTOIN BOUND.
Descriptor:HYDANTOIN TRANSPORT PROTEIN, (5Z)-5-[(3-bromophenyl)methylidene]imidazolidine-2,4-dione, SODIUM ION
Authors:Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1B
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH BENZYL-HYDANTOIN
Descriptor:HYDANTOIN TRANSPORT PROTEIN, (5S)-5-benzylimidazolidine-2,4-dione, SODIUM ION
Authors:Brueckner, F., Geng, T., Weyand, S., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1A
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH INDOLYLMETHYL-HYDANTOIN
Descriptor:HYDANTOIN TRANSPORT PROTEIN, (5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione, SODIUM ION
Authors:Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4BWZ
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CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER, NAPA
Descriptor:NA(+)/H(+) ANTIPORTER, ZINC ION
Authors:Lee, C., Drew, D., Cameron, A.D.
Deposit date:2013-07-05
Release date:2013-08-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.984 Å)
Cite:A two-domain elevator mechanism for sodium/proton antiport.
Nature, 501, 2013
4AU5
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STRUCTURE OF THE NHAA DIMER, CRYSTALLISED AT LOW PH
Descriptor:NA(+)/H(+) ANTIPORTER NHAA, DODECYL-ALPHA-D-MALTOSIDE, SULFATE ION
Authors:Drew, D., Lee, C., Iwata, S., Cameron, A.D.
Deposit date:2012-05-14
Release date:2013-07-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.696 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
4ATV
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STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH
Descriptor:NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION, DODECYL-ALPHA-D-MALTOSIDE
Authors:Drew, D., Lee, C., Iwata, S., Cameron, A.D.
Deposit date:2012-05-10
Release date:2013-07-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
4APS
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CRYSTAL STRUCTURE OF A POT FAMILY PEPTIDE TRANSPORTER IN AN INWARD OPEN CONFORMATION.
Descriptor:DI-OR TRIPEPTIDE H+ SYMPORTER, CADMIUM ION
Authors:Solcan, N., Kwok, J., Fowler, P.W., Cameron, A.D., Drew, D., Iwata, S., Newstead, S.
Deposit date:2012-04-05
Release date:2012-06-13
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Alternating Access Mechanism in the Pot Family of Oligopeptide Transporters.
Embo J., 31, 2012
3ZUY
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CRYSTAL STRUCTURE OF A BACTERIAL HOMOLOGUE OF THE BILE ACID SODIUM SYMPORTER ASBT.
Descriptor:TRANSPORTER, SODIUM ION, TAUROCHOLIC ACID, ...
Authors:Hu, N.-J., Iwata, S., Cameron, A.D., Drew, D.
Deposit date:2011-07-21
Release date:2011-10-12
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Bacterial Homologue of the Bile Acid Sodium Symporter Asbt.
Nature, 478, 2011
3ZUX
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CRYSTAL STRUCTURE OF A BACTERIAL HOMOLOGUE OF THE BILE ACID SODIUM SYMPORTER ASBT.
Descriptor:TRANSPORTER, SODIUM ION, MERCURY (II) ION, ...
Authors:Hu, N.-J., Iwata, S., Cameron, A.D., Drew, D.
Deposit date:2011-07-21
Release date:2011-10-12
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Bacterial Homologue of the Bile Acid Sodium Symporter Asbt.
Nature, 478, 2011
3VGA
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CRYSTAL STRUCTURE OF HUMAN ADENOSINE A2A RECEPTOR WITH AN ALLOSTERIC INVERSE-AGONIST ANTIBODY AT 3.1 A RESOLUTION
Descriptor:Adenosine receptor A2a, antibody fab fragment light chain, antibody fab fragment heavy chain, ...
Authors:Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N., Cameron, A.D., Kobayashi, T., Hamakubo, T., Iwata, S., Murata, T.
Deposit date:2011-08-04
Release date:2012-02-01
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
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