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2UYD
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BU of 2uyd by Molmil
Crystal structure of the SmHasA mutant H83A
Descriptor: ACETATE ION, HEMOPHORE HASA, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Czjzek, M, Caillet-Saguy, C, Fournelle, A, Guigliarelli, B, Izadi-Pruneyre, N, Lecroisey, A.
Deposit date:2007-04-04
Release date:2007-12-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Deciphering the Structural Role of Histidine 83 for Heme Binding in Hemophore Hasa.
J.Biol.Chem., 283, 2008
4AEP
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BU of 4aep by Molmil
HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.8 ANGSTROM
Descriptor: PHOSPHATE ION, RNA-DIRECTED RNA POLYMERASE
Authors:Caillet-Saguy, C, Bressanelli, S.
Deposit date:2012-01-12
Release date:2012-05-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405.
J.Virol., 86, 2012
4AEX
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BU of 4aex by Molmil
HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM in a primitive orthorhombic space group
Descriptor: PHOSPHATE ION, RNA-DIRECTED RNA POLYMERASE
Authors:Caillet-Saguy, C, Bressanelli, S.
Deposit date:2012-01-12
Release date:2012-05-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405.
J.Virol., 86, 2012
2XXD
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BU of 2xxd by Molmil
HCV-JFH1 NS5B polymerase structure at 1.9 angstrom
Descriptor: PHOSPHATE ION, RNA-DIRECTED RNA POLYMERASE
Authors:Caillet-Saguy, C, Bressanelli, S.
Deposit date:2010-11-10
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.881 Å)
Cite:A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes.
J.Virol., 85, 2011
8OEP
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BU of 8oep by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide
Descriptor: Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3
Authors:Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C.
Deposit date:2023-03-11
Release date:2023-05-10
Last modified:2023-05-31
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.
Front Mol Biosci, 10, 2023
8CQY
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BU of 8cqy by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the PBM TACE C-terminal peptide
Descriptor: Disintegrin and metalloproteinase domain-containing protein 17, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3
Authors:Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C.
Deposit date:2023-03-07
Release date:2023-05-10
Last modified:2023-05-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.
Front Mol Biosci, 10, 2023
6HKS
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BU of 6hks by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV16 E6 oncoprotein C-terminal peptide
Descriptor: IODIDE ION, Protein E6, Tyrosine-protein phosphatase non-receptor type 3
Authors:Genera, M, Haouz, A, Caillet-Saguy, C.
Deposit date:2018-09-07
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1944108 Å)
Cite:Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.
Sci Rep, 9, 2019
5EYZ
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BU of 5eyz by Molmil
CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE TAILORED PEPTIDE CYTO8-RETEV
Descriptor: CHLORIDE ION, CYTO8-RETEV, Tyrosine-protein phosphatase non-receptor type 4
Authors:Maisonneuve, P, Vaney, M.C, Babault, B, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N.
Deposit date:2015-11-26
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
J.Biol.Chem., 291, 2016
5EZ0
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BU of 5ez0 by Molmil
CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE PDZ BINDING MOTIF OF THE MITOGEN ACTIVATED PROTEIN KINASE P38GAMMA.
Descriptor: Mitogen-activated protein kinase 12, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 4
Authors:Maisonneuve, P, Vaney, M.C, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N.
Deposit date:2015-11-26
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
J.Biol.Chem., 291, 2016
6Y9P
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BU of 6y9p by Molmil
Crystal structure of Whirlin PDZ3_C-ter in complex with Harmonin a1 C-terminal PDZ binding motif peptide
Descriptor: Harmonin a1, Whirlin
Authors:Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N.
Deposit date:2020-03-10
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.169 Å)
Cite:Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
J.Mol.Biol., 432, 2020
6Y38
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BU of 6y38 by Molmil
Crystal structure of Whirlin PDZ3 in complex with Myosin 15a C-terminal PDZ binding motif peptide
Descriptor: Chains: C,D, Whirlin
Authors:Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N.
Deposit date:2020-02-17
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.697 Å)
Cite:Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
J.Mol.Biol., 432, 2020
6Y9N
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BU of 6y9n by Molmil
Crystal structure of Whirlin PDZ3_C-ter in complex with Myosin 15a C-terminal PDZ binding motif peptide
Descriptor: Unconventional myosin-XV, Whirlin
Authors:Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N.
Deposit date:2020-03-10
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
J.Mol.Biol., 432, 2020
6Y9O
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BU of 6y9o by Molmil
Crystal structure of Whirlin PDZ3_C-ter in complex with CASK internal PDZ binding motif peptide
Descriptor: Peripheral plasma membrane protein CASK, Whirlin
Authors:Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N.
Deposit date:2020-03-10
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.632 Å)
Cite:Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
J.Mol.Biol., 432, 2020
6Y9Q
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BU of 6y9q by Molmil
Crystal structure of Whirlin PDZ3_C-ter in complex with Taperin internal PDZ binding motif peptide
Descriptor: Taperin, Whirlin
Authors:Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N.
Deposit date:2020-03-10
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.315 Å)
Cite:Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
J.Mol.Biol., 432, 2020
7QCR
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BU of 7qcr by Molmil
MLLT4/Afadin PDZ domain in complex with the C-terminal peptide from protein E of SARS-CoV-2
Descriptor: Afadin, Envelope small membrane protein, SULFATE ION
Authors:Zhu, Y, Alvarez, F, Haouz, A, Mechaly, A, Caillet-Saguy, C.
Deposit date:2021-11-25
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins.
Front Microbiol, 13, 2022
7QCS
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BU of 7qcs by Molmil
PALS1/MPP5 PDZ domain in complex with SARS-CoV-2_E PBM peptide
Descriptor: Envelope small membrane protein, Protein PALS1
Authors:Zhu, Y, Alvarez, F, Haouz, A, Mechaly, A, Caillet-Saguy, C.
Deposit date:2021-11-25
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins.
Front Microbiol, 13, 2022
7QCT
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BU of 7qct by Molmil
PDZ2 of LNX2 with SARS-CoV-2_E PBM complex
Descriptor: Envelope small membrane protein, Ligand of Numb protein X 2
Authors:Zhu, Y, Alvarez, F, Haouz, A, Mechaly, A, Caillet-Saguy, C.
Deposit date:2021-11-25
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.197 Å)
Cite:Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins.
Front Microbiol, 13, 2022
6T36
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BU of 6t36 by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HBV core protein C-terminal peptide
Descriptor: BROMIDE ION, Capsid protein, Tyrosine-protein phosphatase non-receptor type 3
Authors:Genera, M, Mechaly, A, Haouz, A, Caillet-Saguy, C.
Deposit date:2019-10-10
Release date:2021-01-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein.
Sci Rep, 11, 2021
2XYM
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BU of 2xym by Molmil
HCV-JFH1 NS5B T385A mutant
Descriptor: PHOSPHATE ION, RNA-DIRECTED RNA POLYMERASE
Authors:Simister, P.C, Caillet-Saguy, C, Bressanelli, S.
Deposit date:2010-11-18
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.774 Å)
Cite:A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes.
J.Virol., 85, 2011
6TWX
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BU of 6twx by Molmil
MAGI1_2 complexed with a phosphorylated 16E6 peptide
Descriptor: 16E6 peptide, CALCIUM ION, CITRIC ACID, ...
Authors:Gogl, G, Cousido-Siah, A, Trave, G.
Deposit date:2020-01-13
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
6TWZ
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BU of 6twz by Molmil
14-3-3 sigma complexed with a phosphorylated 16E6 peptide
Descriptor: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D(-)-TARTARIC ACID, ...
Authors:Gogl, G, Cousido-Siah, A, Sluchanko, N.N, Trave, G.
Deposit date:2020-01-13
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
6TWY
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BU of 6twy by Molmil
MAGI1_2 complexed with a phosphomimetic RSK1 peptide
Descriptor: CALCIUM ION, CITRIC ACID, GLYCEROL, ...
Authors:Gogl, G, Cousido-Siah, A, Trave, G.
Deposit date:2020-01-13
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
6TWU
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BU of 6twu by Molmil
MAGI1_2 complexed with a phosphomimetic 16E6 peptide
Descriptor: CALCIUM ION, CITRIC ACID, GLYCEROL, ...
Authors:Gogl, G, Cousido-Siah, A, Trave, G.
Deposit date:2020-01-13
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
6TWQ
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BU of 6twq by Molmil
MAGI1_2 complexed with a 16E6 peptide
Descriptor: CALCIUM ION, CITRIC ACID, GLYCEROL, ...
Authors:Gogl, G, Cousido-Siah, A, Trave, G.
Deposit date:2020-01-13
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
4ADP
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BU of 4adp by Molmil
HCV-J6 NS5B POLYMERASE V405I MUTANT
Descriptor: RNA-DIRECTED RNA POLYMERASE
Authors:Scrima, N, Bressanelli, S.
Deposit date:2012-01-02
Release date:2012-05-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405.
J.Virol., 86, 2012

 

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