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4FVB
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CRYSTAL STRUCTURE OF EV71 2A PROTEINASE C110A MUTANT
Descriptor:2A proteinase, ZINC ION
Authors:Cai, Q., Muhammad, Y., Liu, W., Gao, Z., Peng, X., Cai, Y., Wu, C., Zheng, Q., Li, J., Lin, T.
Deposit date:2012-06-29
Release date:2013-06-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational Plasticity of 2A Proteinase from Enterovirus 71
J.Virol., 87, 2013
4FVD
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CRYSTAL STRUCTURE OF EV71 2A PROTEINASE C110A MUTANT IN COMPLEX WITH SUBSTRATE
Descriptor:2A proteinase, 10-mer peptide from 2A proteinase, ZINC ION
Authors:Cai, Q., Muhammad, Y., Liu, W., Gao, Z., Peng, X., Cai, Y., Wu, C., Zheng, Q., Li, J., Lin, T.
Deposit date:2012-06-29
Release date:2013-06-19
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Conformational Plasticity of 2A Proteinase from Enterovirus 71
J.Virol., 87, 2013
4GHQ
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE
Descriptor:3C proteinase
Authors:Chen, C., Wu, C., Cai, Q., Li, N., Peng, X., Cai, Y., Yin, K., Chen, X., Wang, X., Zhang, R., Liu, L., Chen, S., Li, J., Lin, T.
Deposit date:2012-08-08
Release date:2013-06-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
4GHT
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH AG7088
Descriptor:3C proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
Authors:Chen, C., Wu, C., Cai, Q., Li, N., Peng, X., Cai, Y., Yin, K., Chen, X., Wang, X., Zhang, R., Liu, L., Chen, S., Li, J., Lin, T.
Deposit date:2012-08-08
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
5DP3
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 2
Descriptor:3C proteinase, ethyl (4S)-5-[(3S)-2-oxopyrrolidin-3-yl]-4-[(3-phenylpropanoyl)amino]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP4
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 3
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[(2S)-2-methyl-3-phenylpropanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP5
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 4
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[(2R,5S)-5-amino-2-(4-fluorobenzyl)-6-methyl-4-oxoheptanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP6
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 7
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[N-(3-cyclopropylpropanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP7
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 5
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[N-(3-methylbutanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP8
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 8
Descriptor:3C proteinase, ethyl (2Z,4S)-4-[(N-{[(2-cyclopropylethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP9
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 9
Descriptor:3C proteinase, ethyl (2Z,4S)-4-[(N-{[(cyclobutylmethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DPA
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 6
Descriptor:3C proteinase, ethyl (2Z,4S)-4-[(N-acetyl-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
3HTO
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THE HEMAGGLUTININ STRUCTURE OF AN AVIAN H1N1 INFLUENZA A VIRUS
Descriptor:Hemagglutinin, Hemagglutinin HA2 chain, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Wang, G., Li, A., Zhang, Q., Wu, C., Zhang, R., Cai, Q., Song, W., Yuen, K.-Y.
Deposit date:2009-06-12
Release date:2009-08-11
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
3HTP
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THE HEMAGGLUTININ STRUCTURE OF AN AVIAN H1N1 INFLUENZA A VIRUS IN COMPLEX WITH LSTA
Descriptor:Hemagglutinin, Hemagglutinin HA2 chain, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Wang, G., Li, A., Zhang, Q., Wu, C., Zhang, R., Cai, Q., Song, W., Yuen, K.-Y.
Deposit date:2009-06-12
Release date:2009-08-11
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
3HTQ
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THE HEMAGGLUTININ STRUCTURE OF AN AVIAN H1N1 INFLUENZA A VIRUS IN COMPLEX WITH LSTC
Descriptor:Hemagglutinin, Hemagglutinin HA2 chain, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Wang, G., Li, A., Zhang, Q., Wu, C., Zhang, R., Cai, Q., Song, W., Yuen, K.-Y.
Deposit date:2009-06-12
Release date:2009-08-11
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (2.955 Å)
Cite:The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
3HTT
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THE HEMAGGLUTININ STRUCTURE OF AN AVIAN H1N1 INFLUENZA A VIRUS IN COMPLEX WITH 2,3-SIALYLLACTOSE
Descriptor:Hemagglutinin, Hemagglutinin HA2 chain, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, G., Li, A., Zhang, Q., Wu, C., Zhang, R., Cai, Q., Song, W., Yuen, K.-Y.
Deposit date:2009-06-12
Release date:2009-08-11
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
4NNG
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STRUCTURAL BASIS FOR TARGETING THE RIBOSOMAL PROTEIN S1 OF MYCOBACTERIUM TUBERCULOSIS BY PYRAZINAMIDE
Descriptor:30S ribosomal protein S1
Authors:Yang, J., Liu, Y., Cai, Q., Lin, D.
Deposit date:2013-11-18
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
4NNH
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STRUCTURAL BASIS FOR TARGETING THE RIBOSOMAL PROTEIN S1 OF MYCOBACTERIUM TUBERCULOSIS BY PYRAZINAMIDE
Descriptor:30S ribosomal protein S1
Authors:Yang, J., Liu, Y., Cai, Q., Lin, D.
Deposit date:2013-11-18
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
4NNI
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STRUCTURAL BASIS FOR TARGETING THE RIBOSOMAL PROTEIN S1 OF MYCOBACTERIUM TUBERCULOSIS BY PYRAZINAMIDE
Descriptor:30S ribosomal protein S1, PYRAZINE-2-CARBOXYLIC ACID
Authors:Yang, J., Liu, Y., Cai, Q., Lin, D.
Deposit date:2013-11-18
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
4NNK
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STRUCTURAL BASIS FOR TARGETING THE RIBOSOMAL PROTEIN S1 OF MYCOBACTERIUM TUBERCULOSIS BY PYRAZINAMIDE
Descriptor:30S ribosomal protein S1
Authors:Yang, J., Liu, Y., Cai, Q., Lin, D.
Deposit date:2013-11-18
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
5C1U
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND XB
Descriptor:3C proteinase, Nalpha-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-enoyl}-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5C1X
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND VIII
Descriptor:3C proteinase, Nalpha-[(benzyloxy)carbonyl]-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5C1Y
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 1
Descriptor:3C proteinase, N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-Nalpha-[(propan-2-yloxy)carbonyl]-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5C20
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 2
Descriptor:3C proteinase, Nalpha-[(2-methylpropoxy)carbonyl]-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5EO3
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CRYSTAL STRUCTURE OF PELOTA C TERMINAL DOMAIN FROM HUMAN
Descriptor:Protein pelota homolog
Authors:Zhang, L., Cai, Q., Lin, T.
Deposit date:2015-11-10
Release date:2016-11-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Purification, crystallization and crystallographic analysis of the Pelota C terminal domian from human
to be published
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