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2YF2
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CRYSTAL STRUCTURE OF THE OLIGOMERISATION DOMAIN OF C4B-BINDING PROTEIN FROM GALLUS GALLUS
Descriptor:C4B BINDING PROTEIN, 1,2-ETHANEDIOL, ACETATE ION
Authors:Caesar, J.J.E., Hill, F., Lea, S.M.
Deposit date:2011-04-01
Release date:2012-04-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Crystal Structure of the Oligomerisation Domain of C4B-Binding Protein from Gallus Gallus
To be Published
4BF3
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ERPC, A MEMBER OF THE COMPLEMENT REGULATOR ACQUIRING FAMILY OF SURFACE PROTEINS FROM BORRELIA BURGDORFEI, POSSESSES AN ARCHITECTURE PREVIOUSLY UNSEEN IN THIS PROTEIN FAMILY.
Descriptor:ERPC, 1,2-ETHANEDIOL
Authors:Caesar, J.J.E., Johnson, S., Kraiczy, P., Lea, S.M.
Deposit date:2013-03-14
Release date:2013-06-05
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Erpc, a Member of the Complement Regulator-Acquiring Family of Surface Proteins from Borrelia Burgdorferi, Possesses an Architecture Previously Unseen in This Protein Family.
Acta Crystallogr.,Sect.F, 69, 2013
4BL4
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FURTHER STRUCTURAL INSIGHTS INTO THE BINDING OF COMPLEMENT FACTOR H BY COMPLEMENT REGULATOR ACQUIRING SURFACE PROTEIN 1, CSPA (BBCRASP-1), OF BORRELIA BURGDORFERI.
Descriptor:COMPLEMENT REGULATOR-ACQUIRING SURFACE PROTEIN 1 (CRASP-1)
Authors:Caesar, J.J.E., Wallich, R., Kraiczy, P., Zipfel, P.F., Lea, S.M.
Deposit date:2013-05-01
Release date:2013-06-05
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (4.06 Å)
Cite:Further Structural Insights Into the Binding of Complement Factor H by Complement Regulator-Acquiring Surface Protein 1 (CspA) of Borrelia Burgdorferi.
Acta Crystallogr.,Sect.F, 69, 2013
3ZD1
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STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2
Descriptor:COMPLEMENT FACTOR H-RELATED PROTEIN 2, 1,2-ETHANEDIOL
Authors:Caesar, J.J.E., Goicoechea de Jorge, E., Pickering, M.C., Lea, S.M.
Deposit date:2012-11-23
Release date:2013-03-13
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZD2
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THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE
Descriptor:COMPLEMENT FACTOR H-RELATED PROTEIN 1, 1,2-ETHANEDIOL
Authors:Caesar, J.J.E., Goicoechea de Jorge, E., Pickering, M.C., Lea, S.M.
Deposit date:2012-11-23
Release date:2013-03-13
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
2W80
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STRUCTURE OF A COMPLEX BETWEEN NEISSERIA MENINGITIDIS FACTOR H BINDING PROTEIN AND CCPS 6-7 OF HUMAN COMPLEMENT FACTOR H
Descriptor:COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN
Authors:Schneider, M.C., Prosser, B.E., Caesar, J.J.E., Kugelberg, E., Li, S., Zhang, Q., Quoraishi, S., Lovett, J.E., Deane, J.E., Sim, R.B., Roversi, P., Johnson, S., Tang, C.M., Lea, S.M.
Deposit date:2009-01-08
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates.
Nature, 458, 2009
2W81
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STRUCTURE OF A COMPLEX BETWEEN NEISSERIA MENINGITIDIS FACTOR H BINDING PROTEIN AND CCPS 6-7 OF HUMAN COMPLEMENT FACTOR H
Descriptor:COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN
Authors:Schneider, M.C., Prosser, B.E., Caesar, J.J.E., Kugelberg, E., Li, S., Zhang, Q., Quoraishi, S., Lovett, J.E., Deane, J.E., Sim, R.B., Roversi, P., Johnson, S., Tang, C.M., Lea, S.M.
Deposit date:2009-01-08
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates.
Nature, 458, 2009
4V1J
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STRUCTURE OF NEISSERIA MENINGITIDIS MAJOR PILLIN
Descriptor:FIMBRIAL PROTEIN, CHLORIDE ION, 1,2-ETHANEDIOL
Authors:Harding, R.J., Exley, R., Tang, C.M., Caesar, J.J.E., Lea, S.M.
Deposit date:2014-09-29
Release date:2016-01-13
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Tstructure of Neisseria Meningitidis Major Pillin
To be Published
2YBY
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STRUCTURE OF DOMAINS 6 AND 7 OF THE MOUSE COMPLEMENT REGULATOR FACTOR H
Descriptor:COMPLEMENT FACTOR H, 1,2-ETHANEDIOL
Authors:Everett, R.J., Caesar, J.J.E., Johnson, S.J., Tang, C.M., Lea, S.M.
Deposit date:2011-03-30
Release date:2012-04-18
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
3ZUI
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OMCI IN COMPLEX WITH PALMITOLEIC ACID
Descriptor:COMPLEMENT INHIBITOR, PALMITOLEIC ACID
Authors:Roversi, P., Maillet, I., Togbe, D., Couillin, I., Quesniaux, V.F.J., Teixeira, M., Ahmat, N., Lissina, O., Boland, W., Ploss, K., Caesar, J.J.E., Leonhartsberger, S., Ryffel, B., Lea, S.M., Nunn, M.A.
Deposit date:2011-07-19
Release date:2012-08-01
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury.
J.Biol.Chem., 288, 2013
3ZUO
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OMCI IN COMPLEX WITH LEUKOTRIENE B4
Descriptor:COMPLEMENT INHIBITOR, LEUKOTRIENE B4
Authors:Roversi, P., Maillet, I., Togbe, D., Couillin, I., Quesniaux, V.F.J., Teixeira, M., Ahmat, N., Lissina, O., Boland, W., Ploss, K., Caesar, J.J.E., Leonhartsberger, S., Ryffel, B., Lea, S.M., Nunn, M.A.
Deposit date:2011-07-19
Release date:2012-08-01
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury.
J.Biol.Chem., 288, 2013
2XRB
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STRUCTURE OF THE N-TERMINAL FOUR DOMAINS OF THE COMPLEMENT REGULATOR RAT CRRY
Descriptor:COMPLEMENT REGULATORY PROTEIN CRRY, SULFATE ION, 1,2-ETHANEDIOL
Authors:Leath, K.J., Roversi, P., Johnson, S., Morgan, B.P., Lea, S.M.
Deposit date:2010-09-13
Release date:2011-06-22
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of the Rat Complement Regulator Crry.
Acta Crystallogr.,Sect.F, 67, 2011
2XRD
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STRUCTURE OF THE N-TERMINAL FOUR DOMAINS OF THE COMPLEMENT REGULATOR RAT CRRY
Descriptor:COMPLEMENT REGULATORY PROTEIN CRRY
Authors:Leath, K.J., Roversi, P., Johnson, S., Morgan, B.P., Lea, S.M.
Deposit date:2010-09-14
Release date:2011-06-22
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structures of the Rat Complement Regulator Crry.
Acta Crystallogr.,Sect.F, 67, 2011