Author results

2V3D
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ACID-BETA-GLUCOSIDASE WITH N-BUTYL-DEOXYNOJIRIMYCIN
Descriptor:GLUCOSYLCERAMIDASE, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ...
Authors:Brumshtein, B., Greenblatt, H.M., Butters, T.D., Shaaltiel, Y., Aviezer, D., Silman, I., Futerman, A.H., Sussman, J.L.
Deposit date:2007-06-17
Release date:2007-08-14
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid Beta-Glucosidase: Insights Into the Mechanism of Chemical Chaperone Action in Gaucher Disease.
J.Biol.Chem., 282, 2007
2V3E
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ACID-BETA-GLUCOSIDASE WITH N-NONYL-DEOXYNOJIRIMYCIN
Descriptor:GLUCOSYLCERAMIDASE, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, (2R,3R,4R,5S)-2-(HYDROXYMETHYL)-1-NONYLPIPERIDINE-3,4,5-TRIOL, ...
Authors:Brumshtein, B., Greenblatt, H.M., Butters, T.D., Shaaltiel, Y., Aviezer, D., Silman, I., Futerman, A.H., Sussman, J.L.
Deposit date:2007-06-17
Release date:2007-08-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid Beta-Glucosidase: Insights Into the Mechanism of Chemical Chaperone Action in Gaucher Disease.
J.Biol.Chem., 282, 2007
4ACY
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SELENOMETHIONINE DERIVATIVE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON
Descriptor:ENDO-ALPHA-MANNOSIDASE, GLYCEROL, FORMIC ACID
Authors:Thompson, A.J., Williams, R.J., Hakki, Z., Alonzi, D.S., Wennekes, T., Gloster, T.M., Songsrirote, K., Thomas-Oates, J.E., Wrodnigg, T.M., Spreitz, J., Stuetz, A.E., Butters, T.D., Williams, S.J., Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4ACZ
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STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON
Descriptor:ENDO-ALPHA-MANNOSIDASE, GLYCEROL
Authors:Thompson, A.J., Williams, R.J., Hakki, Z., Alonzi, D.S., Wennekes, T., Gloster, T.M., Songsrirote, K., Thomas-Oates, J.E., Wrodnigg, T.M., Spreitz, J., Stuetz, A.E., Butters, T.D., Williams, S.J., Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AD0
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STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTERIODES THETAIOTAOMICRON IN COMPLEX WITH BIS-TRIS-PROPANE
Descriptor:ENDO-ALPHA-MANNOSIDASE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL
Authors:Thompson, A.J., Williams, R.J., Hakki, Z., Alonzi, D.S., Wennekes, T., Gloster, T.M., Songsrirote, K., Thomas-Oates, J.E., Wrodnigg, T.M., Spreitz, J., Stuetz, A.E., Butters, T.D., Williams, S.J., Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AD1
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STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS
Descriptor:GLYCOSYL HYDROLASE FAMILY 71
Authors:Thompson, A.J., Williams, R.J., Hakki, Z., Alonzi, D.S., Wennekes, T., Gloster, T.M., Songsrirote, K., Thomas-Oates, J.E., Wrodnigg, T.M., Spreitz, J., Stuetz, A.E., Butters, T.D., Williams, S.J., Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AD2
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STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3-ISOFAGOMINE
Descriptor:GLYCOSYL HYDROLASE FAMILY 71, alpha-D-glucopyranose, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE
Authors:Thompson, A.J., Williams, R.J., Hakki, Z., Alonzi, D.S., Wennekes, T., Gloster, T.M., Songsrirote, K., Thomas-Oates, J.E., Wrodnigg, T.M., Spreitz, J., Stuetz, A.E., Butters, T.D., Williams, S.J., Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AD3
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STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3-DEOXYMANNOJIRIMYCIN
Descriptor:GLYCOSYL HYDROLASE FAMILY 71, alpha-D-glucopyranose, 1-DEOXYMANNOJIRIMYCIN
Authors:Thompson, A.J., Williams, R.J., Hakki, Z., Alonzi, D.S., Wennekes, T., Gloster, T.M., Songsrirote, K., Thomas-Oates, J.E., Wrodnigg, T.M., Spreitz, J., Stuetz, A.E., Butters, T.D., Williams, S.J., Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AD4
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STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3-ISOFAGOMINE AND ALPHA-1,2- MANNOBIOSE
Descriptor:GLYCOSYL HYDROLASE FAMILY 71, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, alpha-D-glucopyranose, ...
Authors:Thompson, A.J., Williams, R.J., Hakki, Z., Alonzi, D.S., Wennekes, T., Gloster, T.M., Songsrirote, K., Thomas-Oates, J.E., Wrodnigg, T.M., Spreitz, J., Stuetz, A.E., Butters, T.D., Williams, S.J., Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AD5
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STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3-DEOXYMANNOJIRIMYCIN AND ALPHA-1,2-MANNOBIOSE
Descriptor:GLYCOSYL HYDROLASE FAMILY 71, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, alpha-D-glucopyranose, ...
Authors:Thompson, A.J., Williams, R.J., Hakki, Z., Alonzi, D.S., Wennekes, T., Gloster, T.M., Songsrirote, K., Thomas-Oates, J.E., Wrodnigg, T.M., Spreitz, J., Stuetz, A.E., Butters, T.D., Williams, S.J., Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
6ZDC
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH NICKEL
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, NICKEL (II) ION
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-14
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZDF
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH HEPES
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-14
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZDK
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH HEPES AND HEXATUNGSTOTELLURATE(VI) TEW
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, ...
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-14
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZDL
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH GLCIFG AND HEXATUNGSTOTELLURATE(VI) TEW
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, ...
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-14
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZFA
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH GLCIFG, ALPHA-1,2-MANNOBIOSE AND HEXATUNGSTOTELLURATE(VI) TEW
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-16
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZFN
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STRUCTURE OF AN INACTIVE E404Q VARIANT OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH 1-METHYL ALPHA-1,2-MANNOBIOSE
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, alpha-D-mannopyranose-(1-2)-methyl alpha-D-mannopyranoside, SULFATE ION
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-17
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZFQ
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH BIS-TRIS
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-17
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZJ1
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STRUCTURE OF AN INACTIVE E404Q VARIANT OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH TETRASACCHARIDE N-GLYCAN FRAGMENT AND HEXATUNGSTOTELLURATE(VI) TEW
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-methyl alpha-D-mannopyranoside, MAGNESIUM ION, ...
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-27
Release date:2020-12-02
Method:X-RAY DIFFRACTION (1.957 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 2020
6ZJ6
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STRUCTURE OF THE GH99 ENDO-ALPHA-MANNANASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH CYCLOHEXYLMETHYL-GLC-1,3-ISOFAGOMINE
Descriptor:Glycosyl hydrolase family 71, 1,2-ETHANEDIOL, ACETATE ION, ...
Authors:Thompson, A.J., Sobala, L.F., Fernandes, P.Z., Hakki, Z., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-27
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
1HNF
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR REGION OF THE HUMAN CELL ADHESION MOLECULE CD2 AT 2.5 ANGSTROMS RESOLUTION
Descriptor:CD2, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION
Authors:Bodian, D.L., Jones, E.Y., Harlos, K., Stuart, D.I., Davis, S.J.
Deposit date:1994-08-10
Release date:1995-02-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution.
Structure, 2, 1994
1HNG
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CRYSTAL STRUCTURE AT 2.8 ANGSTROMS RESOLUTION OF A SOLUBLE FORM OF THE CELL ADHESION MOLECULE CD2
Descriptor:CD2
Authors:Jones, E.Y., Davis, S.J., Williams, A.F., Harlos, K., Stuart, D.I.
Deposit date:1994-08-10
Release date:1995-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2.
Nature, 360, 1992
171916
PDB entries from 2020-12-02