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5K5T
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BU of 5k5t by Molmil
Crystal structure of the inactive form of human calcium-sensing receptor extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Extracellular calcium-sensing receptor, ...
Authors:Geng, Y, Mosyak, L, Kurinov, I, Zuo, H, Sturchler, E, Cheng, T.C, Subramanyam, P, Brown, A.P, Brennan, S.C, Mun, H.-C, Bush, M, Chen, Y, Nguyen, T, Cao, B, Chang, D, Quick, M, Conigrave, A, Colecraft, H.M, McDonald, P, Fan, Q.R.
Deposit date:2016-05-23
Release date:2016-08-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural mechanism of ligand activation in human calcium-sensing receptor.
Elife, 5, 2016
5K5S
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BU of 5k5s by Molmil
Crystal structure of the active form of human calcium-sensing receptor extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Extracellular calcium-sensing receptor, ...
Authors:Geng, Y, Mosyak, L, Kurinov, I, Zuo, H, Sturchler, E, Cheng, T.C, Subramanyam, P, Brown, A.P, Brennan, S.C, Mun, H.-C, Bush, M, Chen, Y, Nguyen, T, Cao, B, Chang, D, Quick, M, Conigrave, A, Colecraft, H.M, McDonald, P, Fan, Q.R.
Deposit date:2016-05-23
Release date:2016-08-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural mechanism of ligand activation in human calcium-sensing receptor.
Elife, 5, 2016
4F12
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BU of 4f12 by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor GBR2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 2
Authors:Geng, Y, Xiong, D, Mosyak, L, Malito, D.L, Kniazeff, J, Chen, Y, Burmakina, S, Quick, M, Bush, M, Javitch, J.A, Pin, J.-P, Fan, Q.R.
Deposit date:2012-05-05
Release date:2012-06-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2.
Nat.Neurosci., 15, 2012
4F11
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BU of 4f11 by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor GBR2
Descriptor: Gamma-aminobutyric acid type B receptor subunit 2
Authors:Geng, Y, Xiong, D, Mosyak, L, Malito, D.L, Kniazeff, J, Chen, Y, Burmakina, S, Quick, M, Bush, M, Javitch, J.A, Pin, J.-P, Fan, Q.R.
Deposit date:2012-05-05
Release date:2012-06-06
Last modified:2012-08-15
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2.
Nat.Neurosci., 15, 2012
4MRM
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BU of 4mrm by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist phaclofen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MQF
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BU of 4mqf by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist 2-hydroxysaclofen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxysaclofen, Gamma-aminobutyric acid type B receptor subunit 1, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-16
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MQE
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BU of 4mqe by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor in the apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-16
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MR7
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BU of 4mr7 by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP54626
Descriptor: (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MR8
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BU of 4mr8 by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP35348
Descriptor: (S)-(3-aminopropyl)(diethoxymethyl)phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MS3
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BU of 4ms3 by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the endogenous agonist GABA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid type B receptor subunit 1, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-18
Release date:2013-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MS1
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BU of 4ms1 by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP46381
Descriptor: (S)-(3-aminopropyl)(cyclohexylmethyl)phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-18
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MR9
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BU of 4mr9 by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist SCH50911
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MS4
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BU of 4ms4 by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the agonist baclofen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-18
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
7LA4
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BU of 7la4 by Molmil
Integrin AlphaIIbBeta3-PT25-2 Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Bush, M.W, Walz, T, Coller, B, Filizola, M, Spasic, A, Nesic, D, Li, J.
Deposit date:2021-01-05
Release date:2022-01-12
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin alpha IIb beta 3 for ligand binding.
Blood Adv, 5, 2021
4KSR
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BU of 4ksr by Molmil
Crystal Structure of the Vibrio cholerae ATPase GspE Hexamer
Descriptor: Type II secretion system protein E, Hemolysin-coregulated protein
Authors:Hol, W.G, Turley, S, Lu, C.Y, Park, Y.J, Marionni, S.T, Lee, K, Patrick, M, Sandkvist, M, Bush, M, Shah, R.
Deposit date:2013-05-17
Release date:2013-09-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Hexamers of the Type II Secretion ATPase GspE from Vibrio cholerae with Increased ATPase Activity.
Structure, 21, 2013

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