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2LMB
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BU of 2lmb by Molmil
Solution Structure of C-terminal RAGE (ctRAGE)
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Rai, V, Maldonado, A.Y, Burz, D.S, Reverdatto, S, Schmidt, A, Shekhtman, A.
Deposit date:2011-11-29
Release date:2011-12-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-terminal rage (ctRAGE) and its binding to mDia1.
J.Biol.Chem., 287, 2012
2MOV
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Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal Derived AGEs.
Descriptor: Advanced glycosylation end product-specific receptor, N~5~-[(5R)-5-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl]-L-ornithine
Authors:Shekhtman, A, Xue, J, Ray, R, Singer, D, Bohme, D, Burz, D.S, Rai, V, Hoffman, R.
Deposit date:2014-05-05
Release date:2014-06-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs.
Biochemistry, 53, 2014
8FG1
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Human diaphanous inhibitory domain bound to diaphanous autoregulatory domain
Descriptor: Protein diaphanous homolog 1
Authors:Ramirez, L.M.S, Theophall, G, Premo, A, Manigrasso, M, Yepuri, G, Burz, D, Ramasamy, R, Schmidt, A.M, Shekhtman, A.
Deposit date:2022-12-12
Release date:2023-10-25
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity.
J.Biol.Chem., 299, 2023
2L7U
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Structure of CEL-PEP-RAGE V domain complex
Descriptor: Advanced glycosylation end product-specific receptor, Serum albumin peptide
Authors:Xue, J, Rai, V, Schmidt, A, Frolov, S, Reverdatto, S, Singer, D, Chabierski, S, Xie, J, Burz, D, Shekhtman, A, Hoffman, R.
Deposit date:2010-12-23
Release date:2011-05-18
Last modified:2023-11-29
Method:SOLUTION NMR
Cite:Advanced glycation end product recognition by the receptor for AGEs.
Structure, 19, 2011
6VXG
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Structure of the C-terminal Domain of RAGE and Its Inhibitor
Descriptor: Advanced glycosylation end product-specific receptor, N-(4-{7-cyano-4-[(morpholin-4-yl)methyl]quinolin-2-yl}phenyl)acetamide
Authors:Ramirez, L, Shekhtman, A.
Deposit date:2020-02-21
Release date:2021-02-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice.
Sci Transl Med, 13, 2021

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