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4UF1
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BU of 4uf1 by Molmil
Deerpox virus DPV022 in complex with Bak BH3
Descriptor: Antiapoptotic membrane protein, Bcl-2 homologous antagonist/killer, SULFATE ION
Authors:Burton, D.R, Kvansakul, M.
Deposit date:2014-12-23
Release date:2015-08-05
Last modified:2021-06-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis.
Acta Crystallogr.,Sect.D, 71, 2015
4UF2
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BU of 4uf2 by Molmil
Deerpox virus DPV022 in complex with Bax BH3
Descriptor: Antiapoptotic membrane protein, Apoptosis regulator BAX
Authors:Burton, D.R, Kvansakul, M.
Deposit date:2014-12-23
Release date:2015-08-05
Last modified:2021-06-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis.
Acta Crystallogr.,Sect.D, 71, 2015
4UF3
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BU of 4uf3 by Molmil
Deerpox virus DPV022 in complex with Bim BH3
Descriptor: Antiapoptotic membrane protein, Bcl-2-like protein 11
Authors:Burton, D.R, Kvansakul, M.
Deposit date:2014-12-23
Release date:2015-08-05
Last modified:2021-06-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis.
Acta Crystallogr.,Sect.D, 71, 2015
7KCR
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BU of 7kcr by Molmil
Cryo-EM structure of Zika virus in complex with E protein cross-linking human monoclonal antibody ADI30056
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADI30056 Fab heavy chain variable region, ADI30056 Fab light chain variable region, ...
Authors:Sevvana, M, Rogers, T.F, Miller, A.S, Long, F, Klose, T, Beutler, N, Lai, Y.C, Parren, M, Walker, L.M, Buda, G, Burton, D.R, Rossmann, M.G, Kuhn, R.J.
Deposit date:2020-10-07
Release date:2020-12-16
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections.
Viruses, 12, 2020
1TZG
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BU of 1tzg by Molmil
Crystal structure of HIV-1 neutralizing human Fab 4E10 in complex with a 13-residue peptide containing the 4E10 epitope on gp41
Descriptor: Envelope polyprotein GP160, Fab 4E10, GLYCEROL
Authors:Cardoso, R.M.F, Zwick, M.B, Stanfield, R.L, Kunert, R, Binley, J.M, Katinger, H, Burton, D.R, Wilson, I.A.
Deposit date:2004-07-09
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41
Immunity, 22, 2005
2FX9
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BU of 2fx9 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41
Descriptor: Fab 4E10, Fragment of HIV glycoprotein gp41
Authors:Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
Deposit date:2006-02-03
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
2FX8
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BU of 2fx8 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with an aib-induced peptide encompassing the 4e10 epitope on gp41
Descriptor: Fab 4E10, Fragment of HIV glycoprotein (GP41)
Authors:Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
Deposit date:2006-02-03
Release date:2006-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
1HZH
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BU of 1hzh by Molmil
CRYSTAL STRUCTURE OF THE INTACT HUMAN IGG B12 WITH BROAD AND POTENT ACTIVITY AGAINST PRIMARY HIV-1 ISOLATES: A TEMPLATE FOR HIV VACCINE DESIGN
Descriptor: IMMUNOGLOBULIN HEAVY CHAIN, IMMUNOGLOBULIN LIGHT CHAIN,Uncharacterized protein, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Saphire, E.O, Burton, D.R, Wilson, I.A.
Deposit date:2001-01-24
Release date:2001-08-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.
Science, 293, 2001
2FX7
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BU of 2fx7 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a 16-residue peptide encompassing the 4e10 epitope on gp41
Descriptor: Fab 4E10, Fragment of HIV glycoprotein (GP41), GLYCEROL
Authors:Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
Deposit date:2006-02-03
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
1CR9
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BU of 1cr9 by Molmil
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4
Descriptor: FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN
Authors:Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E.
Deposit date:1999-08-14
Release date:2000-04-17
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
1CU4
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BU of 1cu4 by Molmil
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 IN COMPLEX WITH ITS PEPTIDE EPITOPE
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, RECOGNITION PEPTIDE
Authors:Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E.
Deposit date:1999-08-20
Release date:2000-04-17
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
6OHY
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BU of 6ohy by Molmil
Chimpanzee SIV Env trimeric ectodomain.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Pallesen, J, Andrabi, R, de Val, N, Burton, D.R, Ward, A.B.
Deposit date:2019-04-08
Release date:2019-06-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template.
Cell Rep, 27, 2019
3HI1
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BU of 3hi1 by Molmil
Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, F105 Heavy Chain, F105 Light Chain, ...
Authors:Kwon, Y.D, Chen, L, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z, Zhang, M.-Y, Arthos, J, Burton, D.R, Dimitrov, D, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D.
Deposit date:2009-05-18
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
3IDX
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BU of 3idx by Molmil
Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C222
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fab b13 heavy chain, ...
Authors:Chen, L, Kwon, Y.D, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z.Y, Zhang, M.Y, Arthos, J, Burton, D.R, Dimitrov, D.S, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D.
Deposit date:2009-07-22
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
3IDY
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BU of 3idy by Molmil
Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab b13 heavy chain, Fab b13 light chain, ...
Authors:Chen, L, Kwon, Y.D, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z.Y, Zhang, M.Y, Arthos, J, Burton, D.R, Dimitrov, D.S, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D.
Deposit date:2009-07-22
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
3INU
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BU of 3inu by Molmil
Crystal structure of an unbound KZ52 neutralizing anti-Ebolavirus antibody.
Descriptor: GLYCEROL, KZ52 antibody fragment heavy chain, KZ52 antibody fragment light chain, ...
Authors:Lee, J.E, Fusco, M.L, Abelson, D.M, Hessell, A.J, Burton, D.R, Saphire, E.O.
Deposit date:2009-08-12
Release date:2009-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Techniques and tactics used in determining the structure of the trimeric ebolavirus glycoprotein.
Acta Crystallogr.,Sect.D, 65, 2009
1N0X
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BU of 1n0x by Molmil
Crystal Structure of a Broadly Neutralizing Anti-HIV-1 Antibody in Complex with a Peptide Mimotope
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, B2.1 peptide, GLYCEROL, ...
Authors:Saphire, E.O, Montero, M, Menendez, A, Irving, M.B, Zwick, M.B, Parren, P.W.H.I, Burton, D.R, Scott, J.K, Wilson, I.A.
Deposit date:2002-10-15
Release date:2004-04-13
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of a Broadly Neutralizing Anti-HIV-1 Antibody in Complex with a Peptide Mimotope
To be Published
3CSY
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BU of 3csy by Molmil
Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing antibody from a human survivor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein GP1, ...
Authors:Lee, J.E, Fusco, M.L, Hessell, A.J, Oswald, W.B, Burton, D.R, Saphire, E.O.
Deposit date:2008-04-10
Release date:2008-07-08
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor.
Nature, 454, 2008
1RHH
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BU of 1rhh by Molmil
Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution
Descriptor: Fab X5, heavy chain, light chain
Authors:Darbha, R, Phogat, S, Labrijn, A.F, Shu, Y, Gu, Y, Andrykovitch, M, Zhang, M.Y, Pantophlet, R, Martin, L, Vita, C, Burton, D.R, Dimitrov, D.S, Ji, X.
Deposit date:2003-11-14
Release date:2004-02-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Broadly Cross-Reactive HIV-1-Neutralizing Fab X5 and Fine Mapping of Its Epitope
Biochemistry, 43, 2004
3U1S
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BU of 3u1s by Molmil
Crystal structure of human Fab PGT145, a broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: Fab PGT145 Heavy chain, Fab PGT145 Light chain, GLYCEROL, ...
Authors:Julien, J.-P, Diwanji, D, Burton, D.R, Wilson, I.A.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
2NY7
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BU of 2ny7 by Molmil
HIV-1 gp120 Envelope Glycoprotein Complexed with the Broadly Neutralizing CD4-Binding-Site Antibody b12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY b12, HEAVY CHAIN, ...
Authors:Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY4
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BU of 2ny4 by Molmil
HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E268C, S334A, S375W) Complexed with CD4 and Antibody 17b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ...
Authors:Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY3
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BU of 2ny3 by Molmil
HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E267C, S334A, S375W) Complexed with CD4 and Antibody 17b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ...
Authors:Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY2
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BU of 2ny2 by Molmil
HIV-1 gp120 Envelope Glycoprotein (T123C, T257S, S334A, S375W, G431C) Complexed with CD4 and Antibody 17b
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, ...
Authors:Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NXY
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HIV-1 gp120 Envelope Glycoprotein(S334A) Complexed with CD4 and Antibody 17b
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, ...
Authors:Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007

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