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2GJS
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BU of 2gjs by Molmil
The crystal structure of human RRAD in complex with GDP
Descriptor: GTP-binding protein RAD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Turnbull, A.P, Yang, X, Soundararajan, M, Schoch, G, Debreczeni, J, Elkins, J.M, Gileadi, C, Berridge, G, Pantic, N, Burgess, N, Smee, C.E.A, Bray, J, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2006-03-31
Release date:2006-04-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human RRAD in complex with GDP
To be Published
2ERY
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BU of 2ery by Molmil
The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein R-Ras2
Authors:Salah, E, Schoch, G, Turnbull, A, Papagrigoriou, E, Soundararajan, M, Burgess, N, Elkins, J, Gileadi, C, Gileadi, O, von Delft, F, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2005-10-25
Release date:2005-11-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state
To be Published
2ERX
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BU of 2erx by Molmil
Crystal Structure of DiRas2 in Complex With GDP and Inorganic Phosphate
Descriptor: GTP-binding protein Di-Ras2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Papagrigoriou, E, Yang, X, Elkins, J, Niesen, F.E, Burgess, N, Salah, E, Fedorov, O, Ball, L.J, von Delft, F, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.
Deposit date:2005-10-25
Release date:2005-11-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of DiRas2
To be Published
2F5Y
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BU of 2f5y by Molmil
Crystal Structure of the PDZ Domain from Human RGS-3
Descriptor: SULFATE ION, regulator of G-protein signalling 3 isoform 1
Authors:Ugochukwu, E, Berridge, G, Johansson, C, Smee, C, Savitsky, P, Burgess, N, Colebrook, S, Yang, X, Elkins, J, Doyle, D, Turnbull, A, Papagrigoriou, E, Debreczeni, J, Bunkoczi, G, Gorrec, F, von Delft, F, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Structural Genomics Consortium (SGC)
Deposit date:2005-11-28
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Crystal Structure of the PDZ Domain from Human RGS-3
To be Published
2G0N
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BU of 2g0n by Molmil
The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ugochukwu, E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2006-02-13
Release date:2006-05-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
To be Published
2FN4
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BU of 2fn4 by Molmil
The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein R-Ras
Authors:Turnbull, A.P, Elkins, J.M, Gileadi, C, Burgess, N, Salah, E, Papagrigoriou, E, Debreczeni, J, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2006-01-10
Release date:2006-01-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state
To be Published
2GF2
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BU of 2gf2 by Molmil
Crystal structure of human hydroxyisobutyrate dehydrogenase
Descriptor: 3-hydroxyisobutyrate dehydrogenase
Authors:Papagrigoriou, E, Salah, E, Turnbull, A.P, Smee, C, Burgess, N, Gileadi, O, von Delft, F, Gorrec, F, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Edwards, A.M, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2006-03-21
Release date:2006-04-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of human hydroxyisobutyrate dehydrogenase
To be Published
2I9P
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BU of 2i9p by Molmil
Crystal structure of human hydroxyisobutyrate dehydrogenase complexed with NAD+
Descriptor: 3-hydroxyisobutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Kavanagh, K.L, Papagrigoriou, E, Salah, E, Lukacik, P, Smee, C, Burgess, N, von Delft, F, Weigelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2006-09-06
Release date:2006-09-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of human hydroxyisobutyrate dehydrogenase complexed with NAD+
To be Published
2NZJ
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BU of 2nzj by Molmil
The crystal structure of REM1 in complex with GDP
Descriptor: CHLORIDE ION, GTP-binding protein REM 1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Turnbull, A.P, Papagrigoriou, E, Ugochukwu, E, Elkins, J.M, Soundararajan, M, Yang, X, Gorrec, F, Umeano, C, Salah, E, Burgess, N, Johansson, C, Berridge, G, Gileadi, O, Bray, J, Marsden, B, Watts, S, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C.H, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2006-11-23
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of REM1 in complex with GDP
To be Published
2OCS
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BU of 2ocs by Molmil
The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2)
Descriptor: 1,2-ETHANEDIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF2, THIOCYANATE ION
Authors:Papagrigoriou, E, Phillips, C, Gileadi, C, Elkins, J, Salah, E, Berridge, G, Savitsky, P, Gorrec, F, Umeano, C, Ugochukwu, E, Gileadi, O, Burgess, N, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2006-12-21
Release date:2007-01-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2)
To be Published
2ODB
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BU of 2odb by Molmil
The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6)
Descriptor: CHLORIDE ION, Human Cell Division Cycle 42 (CDC42), MAGNESIUM ION, ...
Authors:Ugochukwu, E, Yang, X, Elkins, J, Soundararajan, M, Pike, A.C.W, Eswaran, J, Burgess, N, Debreczeni, J.E, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Gileadi, O, von Delft, F, Knapp, S, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2006-12-22
Release date:2007-01-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6)
To be Published
2OVJ
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BU of 2ovj by Molmil
The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP.
Descriptor: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Rac GTPase-activating protein 1
Authors:Shrestha, L, Papagrigoriou, E, Soundararajan, M, Elkins, J, Johansson, C, von Delft, F, Pike, A.C.W, Burgess, N, Turnbull, A, Debreczeni, J, Gorrec, F, Umeano, C, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2007-02-14
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP.
To be Published
2P0A
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BU of 2p0a by Molmil
The crystal structure of human synapsin III (SYN3) in complex with AMPPNP
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Turnbull, A.P, Phillips, C, Pike, A.C.W, Elkins, J.M, Gileadi, C, Salah, E, Niesen, F.H, Burgess, N, Gileadi, O, Gorrec, F, Umeano, C, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C.H, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2007-02-28
Release date:2007-03-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human synapsin III (SYN3) in complex with AMPPNP
To be Published
2ATV
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BU of 2atv by Molmil
The crystal structure of human RERG in the GDP bound state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-like estrogen-regulated growth inhibitor
Authors:Turnbull, A.P, Salah, E, Schoch, G, Elkins, J, Burgess, N, Gileadi, O, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2005-08-26
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human RERG in the GDP bound state
To be Published
2C60
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BU of 2c60 by Molmil
crystal structure of human mitogen-activated protein kinase kinase kinase 3 isoform 2 phox domain at 1.25 A resolution
Descriptor: CALCIUM ION, GLYCEROL, HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 ISOFORM 2
Authors:Debreczeni, J.E, Salah, E, Papagrigoriou, E, Burgess, N, von Delft, F, Gileadi, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Knapp, S.
Deposit date:2005-11-04
Release date:2005-11-29
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase Kinase 3 Isoform 2 Fox Domain at 1.25 A Resolution
To be Published
2C2H
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BU of 2c2h by Molmil
CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP
Descriptor: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Debreczeni, J.E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, von Delft, F, Doyle, D, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A.
Deposit date:2005-09-29
Release date:2005-10-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Human Rac3 in Complex with Gdp
To be Published
3BHH
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BU of 3bhh by Molmil
Crystal structure of human calcium/calmodulin-dependent protein kinase IIB isoform 1 (CAMK2B)
Descriptor: Calcium/calmodulin-dependent protein kinase type II beta chain, [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile
Authors:Filippakopoulos, P, Rellos, P, Niesen, F, Burgess, N, Bullock, A, Berridge, G, Pike, A.C.W, Ugochukwu, E, Pilka, E.S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2007-11-28
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Human Calcium/Calmodulin-Dependent Protein Kinase IIB Isoform 1 (CAMK2B).
To be Published
2UXW
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BU of 2uxw by Molmil
Crystal structure of human very long chain acyl-CoA dehydrogenase (ACADVL)
Descriptor: 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, TRANS DELTA2 PALMITENOYL-COENZYMEA, ...
Authors:Pike, A.C.W, Hozjan, V, Smee, C, Berridge, G, Burgess, N, Salah, E, Bunkoczi, G, Uppenberg, J, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Oppermann, U.
Deposit date:2007-03-30
Release date:2007-05-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl)
To be Published
2I75
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BU of 2i75 by Molmil
Crystal Structure of Human Protein Tyrosine Phosphatase N4 (PTPN4)
Descriptor: SULFATE ION, Tyrosine-protein phosphatase non-receptor type 4
Authors:Ugochukwu, E, Barr, A, Savitsky, P, Burgess, N, Das, S, Turnbull, A, von Delft, F, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2006-08-30
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2AHS
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BU of 2ahs by Molmil
Crystal Structure of the Catalytic Domain of Human Tyrosine Receptor Phosphatase Beta
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Receptor-type tyrosine-protein phosphatase beta, ...
Authors:Ugochukwu, E, Eswaran, J, Barr, A, Gileadi, O, Sobott, F, Burgess, N, Ball, L, Bray, J, von Delft, F, Debreczeni, J, Bunkoczi, G, Turnbull, A, Das, S, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2005-07-28
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2CJZ
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BU of 2cjz by Molmil
crystal structure of the c472s mutant of human protein tyrosine phosphatase ptpn5 (step, striatum enriched phosphatase) in complex with phosphotyrosine
Descriptor: 1,2-ETHANEDIOL, HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5, O-PHOSPHOTYROSINE
Authors:Debreczeni, J.E, Barr, A.J, Eswaran, J, Smee, C, Burgess, N, Gileadi, O, Savitsky, P, Sundstrom, M, Arrowsmith, C, Edwards, A, Weigelt, J, Knapp, S, von Delft, F.
Deposit date:2006-04-10
Release date:2006-05-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2P8U
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BU of 2p8u by Molmil
Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I
Descriptor: COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ...
Authors:Turnbull, A, Shafqat, N, Salah, E, Niesen, F.H, Burgess, N, Bunkoczi, G, Debreczeni, J, Pike, A.C.W, Umeano, C, Gorrec, F, von Delft, F, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2007-03-23
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.
J.Mol.Biol., 398, 2010
2G3Y
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BU of 2g3y by Molmil
Crystal structure of the human small GTPase GEM
Descriptor: GTP-binding protein GEM, GUANOSINE-5'-DIPHOSPHATE
Authors:Ugochukwu, E, Soundararajan, M, Elkins, J, Gileadi, C, Schoch, G, Sobott, F, Fedorov, O, Bray, J, Pantic, N, Berridge, G, Burgess, N, Lee, W.H, Turnbull, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2006-02-21
Release date:2006-04-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human small GTPase GEM
To be Published
2F57
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BU of 2f57 by Molmil
Crystal Structure Of The Human P21-Activated Kinase 5
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE, Serine/threonine-protein kinase PAK 7
Authors:Eswaran, J, Turnbull, A, Ugochukwu, E, Papagrigoriou, E, Bray, J, Das, S, Savitsky, P, Smee, C, Burgess, N, Fedorov, O, Filippakopoulos, P, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2005-11-25
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs.
Structure, 15, 2007
2FCF
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BU of 2fcf by Molmil
The crystal structure of the 7th PDZ domain of MPDZ (MUPP-1)
Descriptor: Multiple PDZ domain protein
Authors:Papagrigoriou, E, Berridge, G, Johansson, C, Colebrook, S, Salah, E, Burgess, N, Smee, C, Savitsky, P, Bray, J, Schoch, G, Phillips, C, Gileadi, C, Soundarajan, M, Yang, X, Elkins, J.M, Gorrec, F, Turnbull, A, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2005-12-12
Release date:2006-01-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007

 

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