Author results

2GJS
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THE CRYSTAL STRUCTURE OF HUMAN RRAD IN COMPLEX WITH GDP
分子名称:GTP-binding protein RAD, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Turnbull, A.P., Yang, X., Soundararajan, M., Schoch, G., Debreczeni, J., Elkins, J.M., Gileadi, C., Berridge, G., Pantic, N., Burgess, N., Smee, C.E.A., Bray, J., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-03-31
公開日2006-04-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of human RRAD in complex with GDP
To be Published
2ATV
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THE CRYSTAL STRUCTURE OF HUMAN RERG IN THE GDP BOUND STATE
分子名称:RAS-like estrogen-regulated growth inhibitor, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Turnbull, A.P., Salah, E., Schoch, G., Elkins, J., Burgess, N., Gileadi, O., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2005-08-26
公開日2005-10-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of human RERG in the GDP bound state
To be Published
2C2H
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CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP
分子名称:RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
著者Debreczeni, J.E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., von Delft, F., Doyle, D., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A.
登録日2005-09-29
公開日2005-10-13
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of the Human Rac3 in Complex with Gdp
To be Published
2C60
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CRYSTAL STRUCTURE OF HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 ISOFORM 2 PHOX DOMAIN AT 1.25 A RESOLUTION
分子名称:HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 ISOFORM 2, CALCIUM ION, GLYCEROL
著者Debreczeni, J.E., Salah, E., Papagrigoriou, E., Burgess, N., von Delft, F., Gileadi, O., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., Knapp, S.
登録日2005-11-04
公開日2005-11-29
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase Kinase 3 Isoform 2 Fox Domain at 1.25 A Resolution
To be Published
2ERX
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CRYSTAL STRUCTURE OF DIRAS2 IN COMPLEX WITH GDP AND INORGANIC PHOSPHATE
分子名称:GTP-binding protein Di-Ras2, PHOSPHATE ION, MAGNESIUM ION, ...
著者Papagrigoriou, E., Yang, X., Elkins, J., Niesen, F.E., Burgess, N., Salah, E., Fedorov, O., Ball, L.J., von Delft, F., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., Doyle, D.
登録日2005-10-25
公開日2005-11-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of DiRas2
To be Published
2ERY
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THE CRYSTAL STRUCTURE OF THE RAS RELATED PROTEIN RRAS2 (RRAS2) IN THE GDP BOUND STATE
分子名称:Ras-related protein R-Ras2, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Salah, E., Schoch, G., Turnbull, A., Papagrigoriou, E., Soundararajan, M., Burgess, N., Elkins, J., Gileadi, C., Gileadi, O., von Delft, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2005-10-25
公開日2005-11-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state
To be Published
2F5Y
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN FROM HUMAN RGS-3
分子名称:regulator of G-protein signalling 3 isoform 1, SULFATE ION
著者Ugochukwu, E., Berridge, G., Johansson, C., Smee, C., Savitsky, P., Burgess, N., Colebrook, S., Yang, X., Elkins, J., Doyle, D., Turnbull, A., Papagrigoriou, E., Debreczeni, J., Bunkoczi, G., Gorrec, F., von Delft, F., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
登録日2005-11-28
公開日2005-12-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal Structure of the PDZ Domain from Human RGS-3
To be Published
2FN4
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THE CRYSTAL STRUCTURE OF HUMAN RAS-RELATED PROTEIN, RRAS, IN THE GDP-BOUND STATE
分子名称:Ras-related protein R-Ras, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Turnbull, A.P., Elkins, J.M., Gileadi, C., Burgess, N., Salah, E., Papagrigoriou, E., Debreczeni, J., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-01-10
公開日2006-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state
To be Published
2G0N
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THE CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP AND CHLORIDE
分子名称:Ras-related C3 botulinum toxin substrate 3, MAGNESIUM ION, CHLORIDE ION, ...
著者Ugochukwu, E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-02-13
公開日2006-05-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
To be Published
2GF2
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CRYSTAL STRUCTURE OF HUMAN HYDROXYISOBUTYRATE DEHYDROGENASE
分子名称:3-hydroxyisobutyrate dehydrogenase
著者Papagrigoriou, E., Salah, E., Turnbull, A.P., Smee, C., Burgess, N., Gileadi, O., von Delft, F., Gorrec, F., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Edwards, A.M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-03-21
公開日2006-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Crystal structure of human hydroxyisobutyrate dehydrogenase
To be Published
2I9P
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CRYSTAL STRUCTURE OF HUMAN HYDROXYISOBUTYRATE DEHYDROGENASE COMPLEXED WITH NAD+
分子名称:3-hydroxyisobutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavanagh, K.L., Papagrigoriou, E., Salah, E., Lukacik, P., Smee, C., Burgess, N., von Delft, F., Weigelt, J., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-09-06
公開日2006-09-26
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of human hydroxyisobutyrate dehydrogenase complexed with NAD+
To be Published
2NZJ
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THE CRYSTAL STRUCTURE OF REM1 IN COMPLEX WITH GDP
分子名称:GTP-binding protein REM 1, MAGNESIUM ION, CHLORIDE ION, ...
著者Turnbull, A.P., Papagrigoriou, E., Ugochukwu, E., Elkins, J.M., Soundararajan, M., Yang, X., Gorrec, F., Umeano, C., Salah, E., Burgess, N., Johansson, C., Berridge, G., Gileadi, O., Bray, J., Marsden, B., Watts, S., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-11-23
公開日2006-12-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of REM1 in complex with GDP
To be Published
2OCS
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THE CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN NHERF-2 (SLC9A3R2)
分子名称:Na(+)/H(+) exchange regulatory cofactor NHE-RF2, THIOCYANATE ION, 1,2-ETHANEDIOL
著者Papagrigoriou, E., Phillips, C., Gileadi, C., Elkins, J., Salah, E., Berridge, G., Savitsky, P., Gorrec, F., Umeano, C., Ugochukwu, E., Gileadi, O., Burgess, N., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-12-21
公開日2007-01-16
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2)
To be Published
2ODB
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THE CRYSTAL STRUCTURE OF HUMAN CDC42 IN COMPLEX WITH THE CRIB DOMAIN OF HUMAN P21-ACTIVATED KINASE 6 (PAK6)
分子名称:Human Cell Division Cycle 42 (CDC42), Serine/threonine-protein kinase PAK 6, CHLORIDE ION, ...
著者Ugochukwu, E., Yang, X., Elkins, J., Soundararajan, M., Pike, A.C.W., Eswaran, J., Burgess, N., Debreczeni, J.E., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Gileadi, O., von Delft, F., Knapp, S., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-12-22
公開日2007-01-30
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6)
To be Published
2OVJ
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THE CRYSTAL STRUCTURE OF THE HUMAN RAC GTPASE ACTIVATING PROTEIN 1 (RACGAP1) MGCRACGAP.
分子名称:Rac GTPase-activating protein 1, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL
著者Shrestha, L., Papagrigoriou, E., Soundararajan, M., Elkins, J., Johansson, C., von Delft, F., Pike, A.C.W., Burgess, N., Turnbull, A., Debreczeni, J., Gorrec, F., Umeano, C., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-02-14
公開日2007-02-27
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP.
To be Published
2P0A
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THE CRYSTAL STRUCTURE OF HUMAN SYNAPSIN III (SYN3) IN COMPLEX WITH AMPPNP
分子名称:Synapsin-3, CHLORIDE ION, SULFATE ION, ...
著者Turnbull, A.P., Phillips, C., Pike, A.C.W., Elkins, J.M., Gileadi, C., Salah, E., Niesen, F.H., Burgess, N., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2007-02-28
公開日2007-03-27
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of human synapsin III (SYN3) in complex with AMPPNP
To be Published
2UXW
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CRYSTAL STRUCTURE OF HUMAN VERY LONG CHAIN ACYL-COA DEHYDROGENASE (ACADVL)
分子名称:VERY-LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Pike, A.C.W., Hozjan, V., Smee, C., Berridge, G., Burgess, N., Salah, E., Bunkoczi, G., Uppenberg, J., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U.
登録日2007-03-30
公開日2007-05-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl)
To be Published
3BHH
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CRYSTAL STRUCTURE OF HUMAN CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE IIB ISOFORM 1 (CAMK2B)
分子名称:Calcium/calmodulin-dependent protein kinase type II beta chain, [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile
著者Filippakopoulos, P., Rellos, P., Niesen, F., Burgess, N., Bullock, A., Berridge, G., Pike, A.C.W., Ugochukwu, E., Pilka, E.S., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Knapp, S., Structural Genomics Consortium (SGC)
登録日2007-11-28
公開日2007-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Human Calcium/Calmodulin-Dependent Protein Kinase IIB Isoform 1 (CAMK2B).
To be Published
2AHS
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN TYROSINE RECEPTOR PHOSPHATASE BETA
分子名称:Receptor-type tyrosine-protein phosphatase beta, CHLORIDE ION, SODIUM ION, ...
著者Ugochukwu, E., Eswaran, J., Barr, A., Gileadi, O., Sobott, F., Burgess, N., Ball, L., Bray, J., von Delft, F., Debreczeni, J., Bunkoczi, G., Turnbull, A., Das, S., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
登録日2005-07-28
公開日2005-08-09
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2CJZ
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CRYSTAL STRUCTURE OF THE C472S MUTANT OF HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP, STRIATUM ENRICHED PHOSPHATASE) IN COMPLEX WITH PHOSPHOTYROSINE
分子名称:HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5, O-PHOSPHOTYROSINE, 1,2-ETHANEDIOL
著者Debreczeni, J.E., Barr, A.J., Eswaran, J., Smee, C., Burgess, N., Gileadi, O., Savitsky, P., Sundstrom, M., Arrowsmith, C., Edwards, A., Weigelt, J., Knapp, S., von Delft, F.
登録日2006-04-10
公開日2006-05-16
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2I75
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CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINE PHOSPHATASE N4 (PTPN4)
分子名称:Tyrosine-protein phosphatase non-receptor type 4, SULFATE ION
著者Ugochukwu, E., Barr, A., Savitsky, P., Burgess, N., Das, S., Turnbull, A., von Delft, F., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., Knapp, S., Structural Genomics Consortium (SGC)
登録日2006-08-30
公開日2006-10-17
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2P8U
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CRYSTAL STRUCTURE OF HUMAN 3-HYDROXY-3-METHYLGLUTARYL COA SYNTHASE I
分子名称:Hydroxymethylglutaryl-CoA synthase, cytoplasmic, COENZYME A, ...
著者Turnbull, A., Shafqat, N., Salah, E., Niesen, F.H., Burgess, N., Bunkoczi, G., Debreczeni, J., Pike, A.C.W., Umeano, C., Gorrec, F., von Delft, F., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-03-23
公開日2007-04-03
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.
J.Mol.Biol., 398, 2010
2G3Y
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CRYSTAL STRUCTURE OF THE HUMAN SMALL GTPASE GEM
分子名称:GTP-binding protein GEM, GUANOSINE-5'-DIPHOSPHATE
著者Ugochukwu, E., Soundararajan, M., Elkins, J., Gileadi, C., Schoch, G., Sobott, F., Fedorov, O., Bray, J., Pantic, N., Berridge, G., Burgess, N., Lee, W.H., Turnbull, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-02-21
公開日2006-04-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the human small GTPase GEM
To be Published
2A3K
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CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE, PTPN7 (HEPTP, HEMATOPOIETIC PROTEIN TYROSINE PHOSPHATASE)
分子名称:protein tyrosine phosphatase, non-receptor type 7, isoform 1, ...
著者Barr, A., Turnbull, A.P., Das, S., Eswaran, J., Debreczeni, J.E., Longmann, E., Smee, C., Burgess, N., Gileadi, O., Sundstrom, M., Arrowsmith, C., Edwards, A., von Delft, F., Knapp, S., Structural Genomics Consortium (SGC)
登録日2005-06-24
公開日2005-07-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1.
Protein Sci., 15, 2006
2BIJ
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CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP, STRIATUM ENRICHED ENRICHED PHOSPHATASE)
分子名称:TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 5, SULFATE ION
著者Barr, A.J., Debreczeni, J.E., Eswaran, J., Smee, C., Burgess, N., Gileadi, O., Sundstrom, M., Arrowsmith, C., Edwards, A., Knapp, S., von Delft, F.
登録日2005-01-21
公開日2005-03-17
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases.
Biochem. J., 395, 2006
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