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5AJ0
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BU of 5aj0 by Molmil
Cryo electron microscopy of actively translating human polysomes (POST state).
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T.
Deposit date:2015-02-19
Release date:2015-05-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Snapshots of Actively Translating Human Ribosomes
Cell(Cambridge,Mass.), 161, 2015
4UJD
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BU of 4ujd by Molmil
mammalian 80S HCV-IRES initiation complex with eIF5B PRE-like state
Descriptor: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S RIBOSOMAL PROTEIN ES1, ...
Authors:Yamamoto, H, Unbehaun, A, Loerke, J, Behrmann, E, Marianne, C, Burger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2014-06-18
Release date:2014-07-30
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Structure of the Mammalian 80S Initiation Complex with Eif5B on Hcv Ires
Nat.Struct.Mol.Biol., 21, 2014
4UJC
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BU of 4ujc by Molmil
mammalian 80S HCV-IRES initiation complex with eIF5B POST-like state
Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES1, ...
Authors:Yamamoto, H, Unbehaun, A, Loerke, J, Behrmann, E, Marianne, C, Burger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2014-06-18
Release date:2014-07-30
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Structure of the Mammalian 80S Initiation Complex with Initiation Factor 5B on Hcv-Ires RNA.
Nat.Struct.Mol.Biol., 21, 2014
5FLX
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BU of 5flx by Molmil
Mammalian 40S HCV-IRES complex
Descriptor: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
Authors:Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T.
Deposit date:2015-10-28
Release date:2015-12-23
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.
Embo J., 34, 2015
7ZNN
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BU of 7znn by Molmil
Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and full-length rat STAT2
Descriptor: B27a, DNA damage-binding protein 1, Signal transducer and activator of transcription, ...
Authors:Lauer, S, Spahn, C.M.T, Schwefel, D.
Deposit date:2022-04-21
Release date:2022-11-09
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor.
Embo J., 42, 2023
7ZN7
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BU of 7zn7 by Molmil
Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and rat STAT2 CCD
Descriptor: B27a, DNA damage-binding protein 1, Signal transducer and activator of transcription, ...
Authors:Lauer, S, Spahn, C.M.T, Schwefel, D.
Deposit date:2022-04-20
Release date:2022-11-09
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor.
Embo J., 42, 2023
7ZJW
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BU of 7zjw by Molmil
Rabbit 80S ribosome as it decodes the Sec-UGA codon
Descriptor: 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ...
Authors:Hilal, T, Simonovic, M, Spahn, C.M.T.
Deposit date:2022-04-12
Release date:2022-10-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Science, 376, 2022
8PEG
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BU of 8peg by Molmil
Escherichia coli paused disome complex (queueing 70S non-rotated closed PRE state)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
Authors:Fluegel, T, Schacherl, M.
Deposit date:2023-06-13
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
3JCJ
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BU of 3jcj by Molmil
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2015-12-18
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
3JCN
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BU of 3jcn by Molmil
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association: Initiation Complex I
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2016-01-04
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
5M1J
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BU of 5m1j by Molmil
Nonstop ribosomal complex bound with Dom34 and Hbs1
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Hilal, T, Yamamoto, H, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2016-10-07
Release date:2017-01-18
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.
Nat Commun, 7, 2016
5LM7
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BU of 5lm7 by Molmil
Crystal structure of the lambda N-Nus factor complex
Descriptor: 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ...
Authors:Said, N, Santos, K, Weber, G, Wahl, M.C.
Deposit date:2016-07-29
Release date:2017-04-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
5LM9
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BU of 5lm9 by Molmil
Structure of E. coli NusA
Descriptor: MAGNESIUM ION, SULFATE ION, Transcription termination/antitermination protein NusA
Authors:Said, N, Weber, G, Santos, K, Wahl, M.C.
Deposit date:2016-07-29
Release date:2017-04-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.143 Å)
Cite:Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
5MS0
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BU of 5ms0 by Molmil
pseudo-atomic model of the RNA polymerase lambda-based antitermination complex solved by cryo-EM
Descriptor: 30S ribosomal protein S10, Antitermination protein N, DNA-directed RNA polymerase subunit alpha, ...
Authors:Said, N, Krupp, F.
Deposit date:2016-12-29
Release date:2017-05-03
Last modified:2018-10-31
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
7PIU
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BU of 7piu by Molmil
Cryo-EM structure of the agonist setmelanotide bound to the active melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein at 2.6 A resolution.
Descriptor: CALCIUM ION, Camelid antibody fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P.
Deposit date:2021-08-23
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide.
Cell Res., 31, 2021
7PIV
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BU of 7piv by Molmil
Active Melanocortin-4 receptor (MC4R)- Gs protein complex bound to agonist NDP-alpha-MSH at 2.86 A resolution.
Descriptor: CALCIUM ION, Camelid antibody VHH fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P.
Deposit date:2021-08-23
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide.
Cell Res., 31, 2021
6GZ3
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BU of 6gz3 by Molmil
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-1 (TI-POST-1)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V.
Deposit date:2018-07-03
Release date:2018-12-05
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
6GZ4
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BU of 6gz4 by Molmil
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-2 (TI-POST-2)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V.
Deposit date:2018-07-03
Release date:2018-12-05
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
6GZ5
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BU of 6gz5 by Molmil
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-3 (TI-POST-3)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V.
Deposit date:2018-07-03
Release date:2018-12-05
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
6Z9T
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BU of 6z9t by Molmil
Transcription termination intermediate complex 5
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Said, N, Hilal, T, Loll, B, Wahl, M.C.
Deposit date:2020-06-04
Release date:2020-11-04
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
6Z9P
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BU of 6z9p by Molmil
Transcription termination intermediate complex 1
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Said, N, Hilal, T, Loll, B, Wahl, M.C.
Deposit date:2020-06-04
Release date:2020-11-04
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
6Z9Q
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BU of 6z9q by Molmil
Transcription termination intermediate complex 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
Authors:Said, N, Hilal, T, Loll, B, Wahl, M.C.
Deposit date:2020-06-04
Release date:2020-11-04
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
6GC8
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BU of 6gc8 by Molmil
50S ribosomal subunit assembly intermediate - 50S rec*
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2018-04-17
Release date:2018-06-20
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC4
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BU of 6gc4 by Molmil
50S ribosomal subunit assembly intermediate state 3
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2018-04-17
Release date:2018-07-04
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC0
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BU of 6gc0 by Molmil
50S ribosomal subunit assembly intermediate state 4
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2018-04-16
Release date:2018-06-20
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018

 

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