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2JED
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THE CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF THE PROTEIN KINASE C THETA IN COMPLEX WITH NVP-XAA228 AT 2.32A RESOLUTION.
Descriptor:PROTEIN KINASE C THETA, 3-(8-DIMETHYLAMINOMETHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]INDOL-10-YL)-4-(1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Stark, W., Bitsch, F., Berner, A., Buelens, F., Graff, P., Depersin, H., Geiser, M., Knecht, R., Rahuel, J., Rummel, G., Schlaeppi, J.M., Schmitz, R., Strauss, A., Wagner, J.
Deposit date:2007-01-16
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:The Crystal Structure of the Kinase Domain of the Protein Kinase C Theta in Complex with Nvp-Xaa228
To be Published
2XG4
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E. COLI P PILUS CHAPERONE-SUBUNIT COMPLEX PAPD-PAPH BOUND TO PILUS BIOGENESIS INHIBITOR, PILICIDE 2C
Descriptor:CHAPERONE PROTEIN PAPD, PAP FIMBRIAL MINOR PILIN PROTEIN, (3R)-8-CYCLOPROPYL-6-(MORPHOLIN-4-YLMETHYL)-7-(1-NAPHTHYLMETHYL)-5-OXO-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID, ...
Authors:Remaut, H., Phan, G., Buelens, F., Chorell, E., Pinkner, J.S., Edvinsson, S., Almqvist, F., Hultgren, S.J., Waksman, G.
Deposit date:2010-05-30
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity.
J.Med.Chem., 53, 2010
2XG5
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E. COLI P PILUS CHAPERONE-SUBUNIT COMPLEX PAPD-PAPH BOUND TO PILUS BIOGENESIS INHIBITOR, PILICIDE 5D
Descriptor:CHAPERONE PROTEIN PAPD, PAP FIMBRIAL MINOR PILIN PROTEIN, GLYCEROL, ...
Authors:Remaut, H., Phan, G., Buelens, F., Chorell, E., Pinkner, J.S., Edvinsson, S., Almqvist, F., Hultgren, S.J., Waksman, G.
Deposit date:2010-05-30
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity.
J.Med.Chem., 53, 2010
2J7L
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E. COLI P PILUS CHAPERONE PAPD IN COMPLEX WITH A PILUS BIOGENESIS INHIBITOR, PILICIDE 2C
Descriptor:CHAPERONE PROTEIN PAPD, (3R)-8-CYCLOPROPYL-6-(MORPHOLIN-4-YLMETHYL)-7-(1-NAPHTHYLMETHYL)-5-OXO-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID
Authors:Remaut, H., Pinkner, J.S., Hultgren, S.J., Almqvist, F., Waksman, G.
Deposit date:2006-10-12
Release date:2006-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Rationally Designed Small Compounds Inhibit Pilus Biogenesis in Uropathogenic Bacteria.
Proc.Natl.Acad.Sci.USA, 103, 2006