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1XYR
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BU of 1xyr by Molmil
Poliovirus 135S cell entry intermediate
Descriptor: Genome polyprotein, Coat protein VP1, Coat protein VP2, ...
Authors:Bubeck, D, Filman, D.J, Cheng, N, Steven, A.C, Hogle, J.M, Belnap, D.M.
Deposit date:2004-11-10
Release date:2005-08-02
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (11 Å)
Cite:The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes.
J.Virol., 79, 2005
3P87
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BU of 3p87 by Molmil
Structure of human PCNA bound to RNASEH2B PIP box peptide
Descriptor: Proliferating cell nuclear antigen, Ribonuclease H2 subunit B
Authors:Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P.
Deposit date:2010-10-13
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39, 2011
3P83
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BU of 3p83 by Molmil
Structure of the PCNA:RNase HII complex from Archaeoglobus fulgidus.
Descriptor: DNA polymerase sliding clamp, Ribonuclease HII
Authors:Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P.
Deposit date:2010-10-13
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39, 2011
8B0F
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BU of 8b0f by Molmil
CryoEM structure of C5b8-CD59
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Bubeck, D, Couves, E.C, Gardner, S.
Deposit date:2022-09-07
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
3P56
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BU of 3p56 by Molmil
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Bubeck, D, Graham, S.C, Jones, E.Y.
Deposit date:2010-10-08
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4.06 Å)
Cite:The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011
3P5J
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BU of 3p5j by Molmil
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Bubeck, D, Graham, S.C, Jones, E.Y.
Deposit date:2010-10-08
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011
8QY4
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BU of 8qy4 by Molmil
Structure of interleukin 11 (gp130 P496L mutant).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ...
Authors:Gardner, S, Bubeck, D, Jin, Y.
Deposit date:2023-10-25
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structure of interleukin 11 (gp130 P496L mutant).
To Be Published
8QY5
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BU of 8qy5 by Molmil
Structure of interleukin 6.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
Authors:Gardner, S, Bubeck, D, Jin, Y.
Deposit date:2023-10-25
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of interleukin 6.
To Be Published
8QY6
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BU of 8qy6 by Molmil
Structure of interleukin 6 (gp130 P496L mutant).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
Authors:Gardner, S, Bubeck, D, Jin, Y.
Deposit date:2023-10-25
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structure of interleukin 6 (gp130 P496L mutant).
To Be Published
6ZD0
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BU of 6zd0 by Molmil
Disulfide-locked early prepore intermedilysin-CD59
Descriptor: CD59 glycoprotein, Thiol-activated cytolysin
Authors:Shah, N.R, Bubeck, D.
Deposit date:2020-06-13
Release date:2020-11-18
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for tuning activity and membrane specificity of bacterial cytolysins.
Nat Commun, 11, 2020
7Z0L
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BU of 7z0l by Molmil
IL-27 signalling complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ...
Authors:Jin, Y, Gardner, S, Bubeck, D.
Deposit date:2022-02-23
Release date:2022-07-27
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural insights into the assembly and activation of the IL-27 signaling complex.
Embo Rep., 23, 2022
8B0H
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BU of 8b0h by Molmil
2C9, C5b9-CD59 cryoEM structure
Descriptor: CD59 glycoprotein, Complement C5, Complement component C6, ...
Authors:Couves, E.C, Gardner, S, Bubeck, D.
Deposit date:2022-09-07
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
8B0G
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BU of 8b0g by Molmil
2C9, C5b9-CD59 structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD59 glycoprotein, Complement C5, ...
Authors:Couves, E.C, Gardner, S, Bubeck, D.
Deposit date:2022-09-07
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
7NYC
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BU of 7nyc by Molmil
cryoEM structure of 3C9-sMAC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Menny, A, Couves, E.C, Bubeck, D.
Deposit date:2021-03-22
Release date:2021-10-06
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
7NYD
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BU of 7nyd by Molmil
cryoEM structure of 2C9-sMAC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Menny, A, Couves, E.C, Bubeck, D.
Deposit date:2021-03-22
Release date:2021-10-06
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
4A5W
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BU of 4a5w by Molmil
Crystal structure of C5b6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ...
Authors:Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P.
Deposit date:2011-10-28
Release date:2012-03-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
4BIK
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BU of 4bik by Molmil
Structure of a disulfide locked mutant of Intermedilysin with human CD59
Descriptor: CD59 GLYCOPROTEIN, INTERMEDILYSIN
Authors:Johnson, S, Brooks, N.J, Smith, R.A.G, Lea, S.M, Bubeck, D.
Deposit date:2013-04-10
Release date:2013-05-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.494 Å)
Cite:Structural Basis for Recognition of the Pore- Forming Toxin Intermedilysin by Human Complement Receptor Cd59
Cell Rep., 3, 2013
6GVE
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BU of 6gve by Molmil
GAPDH-CP12-PRK complex
Descriptor: CP12 polypeptide, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:McFarlane, C.R, Shah, N, Bubeck, D, Murray, J.W.
Deposit date:2018-06-20
Release date:2019-07-03
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of light-induced redox regulation in the Calvin-Benson cycle in cyanobacteria.
Proc.Natl.Acad.Sci.USA, 116, 2019
6H03
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BU of 6h03 by Molmil
OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ...
Authors:Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D.
Deposit date:2018-07-06
Release date:2018-12-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
6H04
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BU of 6h04 by Molmil
Closed conformation of the Membrane Attack Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ...
Authors:Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D.
Deposit date:2018-07-06
Release date:2018-12-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
2N59
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BU of 2n59 by Molmil
Solution Structure of R. palustris CsgH
Descriptor: Putative uncharacterized protein CsgH
Authors:Hawthorne, W.J, Taylor, J.D, Escalera-Maurer, A, Lambert, S, Koch, M, Scull, N, Sefer, L, Xu, Y, Matthews, S.J.
Deposit date:2015-07-13
Release date:2016-05-11
Method:SOLUTION NMR
Cite:Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones.
Sci Rep, 6, 2016
8C6I
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BU of 8c6i by Molmil
TMEM2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Hohenester, E.
Deposit date:2023-01-11
Release date:2023-02-01
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the transmembrane protein 2 (TMEM2) ectodomain and its apparent lack of hyaluronidase activity.
Wellcome Open Res, 8, 2023
4A0P
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BU of 4a0p by Molmil
Crystal structure of LRP6P3E3P4E4
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, S, Malinauskas, T, Aricescu, A.R, Siebold, C, Jones, E.Y.
Deposit date:2011-09-11
Release date:2011-10-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Studies of Lrp6 Ectodomain Reveal a Platform for Wnt Signaling.
Dev.Cell, 21, 2011
6GHL
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BU of 6ghl by Molmil
cyanobacterial GAPDH with full-length CP12
Descriptor: CP12 polypeptide, Glyceraldehyde-3-phosphate dehydrogenase, MALONATE ION, ...
Authors:McFarlane, C.R, Murray, J.W.
Deposit date:2018-05-08
Release date:2019-05-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.378 Å)
Cite:Structural basis of light-induced redox regulation in the Calvin-Benson cycle in cyanobacteria.
Proc.Natl.Acad.Sci.USA, 116, 2019
6GFR
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BU of 6gfr by Molmil
cyanobacterial GAPDH with NAD
Descriptor: ACETATE ION, Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION, ...
Authors:McFarlane, C.R, Murray, J.W.
Deposit date:2018-05-01
Release date:2019-05-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.919 Å)
Cite:Structural basis of light-induced redox regulation in the Calvin-Benson cycle in cyanobacteria.
Proc.Natl.Acad.Sci.USA, 116, 2019

 

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