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1KNC
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STRUCTURE OF AHPD FROM MYCOBACTERIUM TUBERCULOSIS, A NOVEL ENZYME WITH THIOREDOXIN-LIKE ACTIVITY.
Descriptor:AhpD protein, SULFATE ION
Authors:Bryk, R., Lima, C.D., Erdjument-Bromage, H., Tempst, P., Nathan, C.
Deposit date:2001-12-18
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein.
Science, 295, 2002
2A8X
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CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Rajashankar, K.R., Bryk, R., Kniewel, R., Buglino, J.A., Nathan, C.F., Lima, C.D.
Deposit date:2005-07-10
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis
J.Biol.Chem., 280, 2005
3II4
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STRUCTURE OF MYCOBACTERIAL LIPOAMIDE DEHYDROGENASE BOUND TO A TRIAZASPIRODIMETHOXYBENZOYL INHIBITOR
Descriptor:Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, N-[2-(2,4-dichlorophenyl)ethyl]-2-{8-[(2,4-dimethoxyphenyl)carbonyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl}acetamide
Authors:Lima, C.D.
Deposit date:2009-07-31
Release date:2010-01-26
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase .
Biochemistry, 49, 2010
4M52
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STRUCTURE OF MTB LPD BOUND TO SL827
Descriptor:Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, N~2~-[(2-amino-5-bromopyridin-3-yl)sulfonyl]-N-(4-methoxyphenyl)-N~2~-methylglycinamide
Authors:Lima, C.D.
Deposit date:2013-08-07
Release date:2013-11-27
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase.
Biochemistry, 52, 2013