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1GVE
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BU of 1gve by Molmil
Aflatoxin aldehyde reductase (AKR7A1) from Rat Liver
Descriptor: AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3, CITRIC ACID, GLYCEROL, ...
Authors:Kozma, E, Brown, E, Ellis, E.M, Lapthorn, A.J.
Deposit date:2002-02-08
Release date:2002-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:The Crystal Structure of Rat Liver Akr7A1: A Dimeric Member of the Aldo-Keto Reductase Superfamily
J.Biol.Chem., 277, 2002
4L39
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BU of 4l39 by Molmil
Crystal structure of GH3.12 from Arabidopsis thaliana in complex with AMPCPP and salicylate
Descriptor: 2-HYDROXYBENZOIC ACID, 4-substituted benzoates-glutamate ligase GH3.12, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Zubieta, C, Jez, J.M, Brown, E, Marcellin, R, Kapp, U, Round, A, Westfall, C.
Deposit date:2013-06-05
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Determination of the GH3.12 protein conformation through HPLC-integrated SAXS measurements combined with X-ray crystallography.
Acta Crystallogr.,Sect.D, 69, 2013
6Q2A
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BU of 6q2a by Molmil
Trypanosoma brucei CLK1 kinase domain in complex with a covalent aminobenzimidazole inhibitor AB1
Descriptor: Protein kinase, putative, SULFATE ION, ...
Authors:Ma, X, Ornelas, E.
Deposit date:2019-08-07
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors.
Nat Microbiol, 5, 2020
8U7X
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BU of 8u7x by Molmil
Crystal structure of non-receptor protein tyrosine phosphatase SHP2 in complex with inhibitor compound 24
Descriptor: (3S,4S)-8-{6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]pyrido[2,3-b]pyrazin-2-yl}-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine, Tyrosine-protein phosphatase non-receptor type 11
Authors:Mou, T.C.
Deposit date:2023-09-15
Release date:2024-01-03
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Discovery of 5-Azaquinoxaline Derivatives as Potent and Orally Bioavailable Allosteric SHP2 Inhibitors.
Acs Med.Chem.Lett., 14, 2023
8U7W
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BU of 8u7w by Molmil
Crystal structure of non-receptor protein tyrosine phosphatase SHP2 in complex with inhibitor compound 7
Descriptor: 1-{6-[(2,3-dichlorophenyl)sulfanyl]pyrido[2,3-b]pyrazin-2-yl}-4-methylpiperidin-4-amine, Tyrosine-protein phosphatase non-receptor type 11
Authors:Mou, T.C.
Deposit date:2023-09-15
Release date:2024-01-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Discovery of 5-Azaquinoxaline Derivatives as Potent and Orally Bioavailable Allosteric SHP2 Inhibitors.
Acs Med.Chem.Lett., 14, 2023
8B7D
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BU of 8b7d by Molmil
Luminal domain of TMEM106B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Pye, V.E, Roustan, C, Cherepanov, P.
Deposit date:2022-09-29
Release date:2023-07-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry.
Cell, 186, 2023
3JVS
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BU of 3jvs by Molmil
Characterization of the Chk1 allosteric inhibitor binding site
Descriptor: 2-[(4-tert-butyl-3-nitrophenyl)carbonyl]-N-naphthalen-1-ylhydrazinecarboxamide, Serine/threonine-protein kinase Chk1
Authors:Chen, P.
Deposit date:2009-09-17
Release date:2009-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of the CHK1 allosteric inhibitor binding site.
Biochemistry, 48, 2009
3JVR
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BU of 3jvr by Molmil
Characterization of the Chk1 allosteric inhibitor binding site
Descriptor: (1S)-1-(1H-benzimidazol-2-yl)ethyl (3,4-dichlorophenyl)carbamate, Serine/threonine-protein kinase Chk1
Authors:Chen, P.
Deposit date:2009-09-17
Release date:2009-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Characterization of the CHK1 allosteric inhibitor binding site.
Biochemistry, 48, 2009
4OX0
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BU of 4ox0 by Molmil
Crystal structure of the keratin-like domain from the MADS transcription factor Sepallata 3
Descriptor: Developmental protein SEPALLATA 3
Authors:Zubieta, C, Acajjaoui, C.
Deposit date:2014-02-04
Release date:2014-10-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural Basis for the Oligomerization of the MADS Domain Transcription Factor SEPALLATA3 in Arabidopsis.
Plant Cell, 26, 2014
4HMM
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BU of 4hmm by Molmil
Crystal structure of mutant rabbit PRP 121-230 (S174N)
Descriptor: CHLORIDE ION, GLYCEROL, Major prion protein, ...
Authors:Sweeting, B, Chakrabartty, A, Pai, E.F.
Deposit date:2012-10-18
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:N-Terminal Helix-Cap in alpha-Helix 2 Modulates beta-State Misfolding in Rabbit and Hamster Prion Proteins.
Plos One, 8, 2013
4HLS
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BU of 4hls by Molmil
Crystal structure of mutant rabbit PRP 121-230 (S170N)
Descriptor: CHLORIDE ION, GLYCEROL, Major prion protein, ...
Authors:Sweeting, B, Chakrabartty, A, Pai, E.F.
Deposit date:2012-10-17
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:N-Terminal Helix-Cap in alpha-Helix 2 Modulates beta-State Misfolding in Rabbit and Hamster Prion Proteins.
Plos One, 8, 2013
4HMR
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BU of 4hmr by Molmil
Crystal structure of mutant rabbit PRP 121-230 (S170N/S174N)
Descriptor: CHLORIDE ION, GLYCEROL, Major prion protein, ...
Authors:Sweeting, B, Chakrabartty, A, Pai, E.F.
Deposit date:2012-10-18
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:N-Terminal Helix-Cap in alpha-Helix 2 Modulates beta-State Misfolding in Rabbit and Hamster Prion Proteins.
Plos One, 8, 2013

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