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6AUI
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BU of 6aui by Molmil
Human ribonucleotide reductase large subunit (alpha) with dATP and CDP
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Brignole, E.J, Drennan, C.L, Asturias, F.J, Tsai, K.L, Penczek, P.A.
Deposit date:2017-09-01
Release date:2018-04-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:3.3- angstrom resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound.
Elife, 7, 2018
7MDI
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BU of 7mdi by Molmil
Structure of the Neisseria gonorrhoeae ribonucleotide reductase in the inactive state
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Levitz, T.S, Drennan, C.L, Brignole, E.J.
Deposit date:2021-04-05
Release date:2022-01-05
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Effects of chameleon dispense-to-plunge speed on particle concentration, complex formation, and final resolution: A case study using the Neisseria gonorrhoeae ribonucleotide reductase inactive complex.
J.Struct.Biol., 214, 2021
6CET
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BU of 6cet by Molmil
Cryo-EM structure of GATOR1
Descriptor: GATOR complex protein DEPDC5, GATOR complex protein NPRL2, GATOR complex protein NPRL3
Authors:Shen, K, Huang, R.K, Brignole, E.J, Yu, Z, Sabatini, D.M.
Deposit date:2018-02-12
Release date:2018-03-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
Nature, 556, 2018
6CES
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BU of 6ces by Molmil
Cryo-EM structure of GATOR1-RAG
Descriptor: GATOR complex protein DEPDC5, GATOR complex protein NPRL2, GATOR complex protein NPRL3, ...
Authors:Shen, K, Huang, R.K, Brignole, E.J, Yu, Z, Sabatini, D.M.
Deposit date:2018-02-12
Release date:2018-03-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
Nature, 556, 2018
5C4I
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BU of 5c4i by Molmil
Structure of an Oxalate Oxidoreductase
Descriptor: IRON/SULFUR CLUSTER, MAGNESIUM ION, Oxalate oxidoreductase subunit alpha, ...
Authors:Gibson, M.I, Brignole, E.J, Pierce, E, Can, M, Ragsdale, S.W, Drennan, C.L.
Deposit date:2015-06-18
Release date:2015-07-01
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.274 Å)
Cite:The Structure of an Oxalate Oxidoreductase Provides Insight into Microbial 2-Oxoacid Metabolism.
Biochemistry, 54, 2015
5D1Y
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BU of 5d1y by Molmil
Low resolution crystal structure of human ribonucleotide reductase alpha6 hexamer in complex with dATP
Descriptor: Ribonucleoside-diphosphate reductase large subunit
Authors:Ando, N, Li, H, Brignole, E.J, Thompson, S, McLaughlin, M.I, Page, J, Asturias, F, Stubbe, J, Drennan, C.L.
Deposit date:2015-08-04
Release date:2016-01-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (9.005 Å)
Cite:Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer.
Biochemistry, 55, 2016
7UHY
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BU of 7uhy by Molmil
Human GATOR2 complex
Descriptor: GATOR complex protein MIOS, GATOR complex protein WDR24, GATOR complex protein WDR59, ...
Authors:Rogala, K.B, Valenstein, M.L, Lalgudi, P.V.
Deposit date:2022-03-27
Release date:2022-07-20
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structure of the nutrient-sensing hub GATOR2.
Nature, 607, 2022
4ERP
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BU of 4erp by Molmil
Crystal structure of a gemcitabine-diphosphate inhibited E. coli class Ia ribonucleotide reductase complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 subunit alpha, ...
Authors:Zimanyi, C.M, Drennan, C.L.
Deposit date:2012-04-20
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.45 Å)
Cite:Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.
Structure, 20, 2012
5USR
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BU of 5usr by Molmil
Crystal structure of human NFS1-ISD11 in complex with E. coli acyl-carrier protein at 3.09 angstroms
Descriptor: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
Authors:Cory, S.A, Barondeau, D.P.
Deposit date:2017-02-13
Release date:2017-06-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7PER
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BU of 7per by Molmil
Model of the inner ring of the human nuclear pore complex
Descriptor: Nuclear pore complex protein Nup155, Nuclear pore complex protein Nup205, Nuclear pore complex protein Nup93, ...
Authors:Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U.
Deposit date:2021-08-11
Release date:2021-10-20
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (35 Å)
Cite:The cellular environment shapes the nuclear pore complex architecture.
Nature, 598, 2021
7PEQ
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BU of 7peq by Molmil
Model of the outer rings of the human nuclear pore complex
Descriptor: Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133, Nuclear pore complex protein Nup160, ...
Authors:Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U.
Deposit date:2021-08-11
Release date:2021-10-20
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (35 Å)
Cite:The cellular environment shapes the nuclear pore complex architecture.
Nature, 598, 2021
6U62
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BU of 6u62 by Molmil
Raptor-Rag-Ragulator complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Rogala, K.B, Sabatini, D.M.
Deposit date:2019-08-29
Release date:2019-10-30
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural basis for the docking of mTORC1 on the lysosomal surface.
Science, 366, 2019
8USQ
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BU of 8usq by Molmil
Structural and biochemical investigations of a HEAT-repeat protein involved in the cytosolic iron-sulfur cluster assembly pathway
Descriptor: DNA repair/transcription protein MET18/MMS19
Authors:Vasquez, S, Drennan, C.L.
Deposit date:2023-10-29
Release date:2023-12-27
Last modified:2024-01-10
Method:ELECTRON MICROSCOPY (12.77 Å)
Cite:Structural and biochemical investigations of a HEAT-repeat protein involved in the cytosolic iron-sulfur cluster assembly pathway
Commun Biol, 6, 2023
8USP
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BU of 8usp by Molmil
Structural and biochemical investigations of a HEAT-repeat protein involved in the cytosolic iron-sulfur cluster assembly pathway
Descriptor: DNA repair/transcription protein MET18/MMS19
Authors:Vasquez, S, Drennan, C.L.
Deposit date:2023-10-28
Release date:2023-12-27
Last modified:2024-01-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and biochemical investigations of a HEAT-repeat protein involved in the cytosolic iron-sulfur cluster assembly pathway
Commun Biol, 6, 2023
3UUS
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BU of 3uus by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit alpha, ...
Authors:Zimanyi, C.M, Drennan, C.L.
Deposit date:2011-11-28
Release date:2011-12-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (5.65 Å)
Cite:Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase.
Proc.Natl.Acad.Sci.USA, 108, 2011
4ERM
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BU of 4erm by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex at 4 Angstroms resolution
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Zimanyi, C.M, Drennan, C.L.
Deposit date:2012-04-20
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.
Structure, 20, 2012
7JUA
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BU of 7jua by Molmil
Crystal structure of the second heterocyclization domain of yersiniabactin synthetase at 2.35 A resolution
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Irp2 protein, SODIUM ION
Authors:Xia, Y, Soule, J, Dowling, D.P.
Deposit date:2020-08-19
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding.
J.Biol.Chem., 2022
7JTJ
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BU of 7jtj by Molmil
Crystal structure of the second heterocyclization domain of yersiniabactin synthetase
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Irp2 protein, SODIUM ION
Authors:Xia, Y, Gnann, A.D, Dowling, D.P.
Deposit date:2020-08-17
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding.
J.Biol.Chem., 298, 2022

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