1QSL | |
2KFN | | KLENOW FRAGMENT WITH BRIDGING-SULFUR SUBSTRATE AND MANGANESE | | Descriptor: | 5'-D(*GP*CP*TP*TP*AP*(US1)P*G)-3', KLENOW FRAGMENT OF DNA POLYMERASE I, MANGANESE (II) ION, ... | | Authors: | Brautigam, C.A., Sun, S., Piccirilli, J.A., Steitz, T.A. | | Deposit date: | 1998-07-01 | | Release date: | 1998-11-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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2KFZ | | KLENOW FRAGMENT WITH BRIDGING-SULFUR SUBSTRATE AND ZINC ONLY | | Descriptor: | 5'-D(*GP*CP*TP*TP*AP*(US1)P*G)-3', KLENOW FRAGMENT OF DNA POLYMERASE I, ZINC ION, ... | | Authors: | Brautigam, C.A., Sun, S., Piccirilli, J.A., Steitz, T.A. | | Deposit date: | 1998-07-02 | | Release date: | 1998-11-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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2KZM | | KLENOW FRAGMENT WITH NORMAL SUBSTRATE AND ZINC AND MANGANESE | | Descriptor: | DNA (5'-D(*GP*CP*TP*TP*A*CP*GP*C)-3'), PROTEIN (DNA POLYMERASE I), MANGANESE (II) ION, ... | | Authors: | Brautigam, C.A., Sun, S., Piccirilli, J.A., Steitz, T.A. | | Deposit date: | 1998-07-03 | | Release date: | 1999-02-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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2KZZ | | KLENOW FRAGMENT WITH NORMAL SUBSTRATE AND ZINC ONLY | | Descriptor: | DNA (5'-D(*GP*CP*TP*T*AP*CP*G)-3'), PROTEIN (DNA POLYMERASE I), ZINC ION | | Authors: | Brautigam, C.A., Sun, S., Piccirilli, J.A., Steitz, T.A. | | Deposit date: | 1998-07-07 | | Release date: | 1999-12-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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4U3Q | |
1KFS | | DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX | | Descriptor: | DNA (5'-D(*GP*CP*TP*TP*AP*CP*G)-3'), PROTEIN (DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7)), MAGNESIUM ION, ... | | Authors: | Brautigam, C.A., Steitz, T.A. | | Deposit date: | 1997-08-18 | | Release date: | 1998-02-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates.
J.Mol.Biol., 277, 1998
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1KRP | | DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX | | Descriptor: | DNA (5'-D(P*TP*TP*PST)-3'), PROTEIN (DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7)), ZINC ION | | Authors: | Brautigam, C.A., Steitz, T.A. | | Deposit date: | 1997-08-19 | | Release date: | 1998-02-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates.
J.Mol.Biol., 277, 1998
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1KSP | | DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX | | Descriptor: | DNA (5'-D(P*TP*TP*PST)-3'), PROTEIN (DNA POLYMERASE I-KLENOW FRAGMENT (E.C.2.7.7.7)), ZINC ION | | Authors: | Brautigam, C.A., Steitz, T.A. | | Deposit date: | 1997-08-19 | | Release date: | 1998-02-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates.
J.Mol.Biol., 277, 1998
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1PK8 | | CRYSTAL STRUCTURE OF RAT SYNAPSIN I C DOMAIN COMPLEXED TO CA.ATP | | Descriptor: | rat synapsin I, CALCIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Brautigam, C.A., Chelliah, Y., Deisenhofer, J. | | Deposit date: | 2003-06-05 | | Release date: | 2004-03-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I.
J.Biol.Chem., 279, 2004
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1PX2 | | CRYSTAL STRUCTURE OF RAT SYNAPSIN I C DOMAIN COMPLEXED TO CA.ATP (FORM 1) | | Descriptor: | Synapsin I, CALCIUM ION, ADENOSINE-5'-TRIPHOSPHATE | | Authors: | Brautigam, C.A., Chelliah, Y., Deisenhofer, J. | | Deposit date: | 2003-07-02 | | Release date: | 2004-03-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I.
J.Biol.Chem., 279, 2004
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1U3C | | CRYSTAL STRUCTURE OF THE PHR DOMAIN OF CRYPTOCHROME 1 FROM ARABIDOPSIS THALIANA | | Descriptor: | Cryptochrome 1 apoprotein, MAGNESIUM ION, CHLORIDE ION, ... | | Authors: | Brautigam, C.A., Smith, B.S., Ma, Z., Palnitkar, M., Tomchick, D.R., Machius, M., Deisenhofer, J. | | Deposit date: | 2004-07-21 | | Release date: | 2004-08-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1U3D | | CRYSTAL STRUCTURE OF THE PHR DOMAIN OF CRYPTOCHROME 1 FROM ARABIDOPSIS THALIANA WITH AMPPNP BOUND | | Descriptor: | Cryptochrome 1 apoprotein, MAGNESIUM ION, CHLORIDE ION, ... | | Authors: | Brautigam, C.A., Smith, B.S., Ma, Z., Palnitkar, M., Tomchick, D.R., Machius, M., Deisenhofer, J. | | Deposit date: | 2004-07-21 | | Release date: | 2004-08-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1ZMC | | CRYSTAL STRUCTURE OF HUMAN DIHYDROLIPOAMIDE DEHYDROGENASE COMPLEXED TO NAD+ | | Descriptor: | Dihydrolipoyl dehydrogenase, mitochondrial, SULFATE ION, ... | | Authors: | Brautigam, C.A., Chuang, J.L., Tomchick, D.R., Machius, M., Chuang, D.T. | | Deposit date: | 2005-05-10 | | Release date: | 2005-06-28 | | Last modified: | 2019-11-13 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Crystal Structure of Human Dihydrolipoamide Dehydrogenase: NAD(+)/NADH Binding and the Structural Basis of Disease-causing Mutations
J.Mol.Biol., 350, 2005
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1ZMD | | CRYSTAL STRUCTURE OF HUMAN DIHYDROLIPOAMIDE DEHYDROGENASE COMPLEXED TO NADH | | Descriptor: | Dihydrolipoyl dehydrogenase, SULFATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Brautigam, C.A., Chuang, J.L., Tomchick, D.R., Machius, M., Chuang, D.T. | | Deposit date: | 2005-05-10 | | Release date: | 2005-06-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Crystal Structure of Human Dihydrolipoamide Dehydrogenase: NAD+/NADH Binding and the Structural Basis of Disease-causing Mutations
J.Mol.Biol., 350, 2005
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2F5Z | | CRYSTAL STRUCTURE OF HUMAN DIHYDROLIPOAMIDE DEHYDROGENASE (E3) COMPLEXED TO THE E3-BINDING DOMAIN OF HUMAN E3-BINDING PROTEIN | | Descriptor: | Dihydrolipoyl dehydrogenase, Pyruvate dehydrogenase protein X component, SULFATE ION, ... | | Authors: | Brautigam, C.A., Chuang, J.L., Wynn, R.M., Tomchick, D.R., Machius, M., Chuang, D.T. | | Deposit date: | 2005-11-28 | | Release date: | 2006-01-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Structural Insight into Interactions between Dihydrolipoamide Dehydrogenase (E3) and E3 Binding Protein of Human Pyruvate Dehydrogenase Complex.
Structure, 14, 2006
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2F60 | | CRYSTAL STRUCTURE OF THE DIHYDROLIPOAMIDE DEHYDROGENASE (E3)-BINDING DOMAIN OF HUMAN E3-BINDING PROTEIN | | Descriptor: | Pyruvate dehydrogenase protein X component, GLYCEROL | | Authors: | Brautigam, C.A., Chuang, J.L., Wynn, R.M., Tomchick, D.R., Machius, M., Chuang, D.T. | | Deposit date: | 2005-11-28 | | Release date: | 2006-01-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural Insight into Interactions between Dihydrolipoamide Dehydrogenase (E3) and E3 Binding Protein of Human Pyruvate Dehydrogenase Complex.
Structure, 14, 2006
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3PJL | | THE CRYSTAL STRUCTURE OF TP34 BOUND TO CO (II) ION AT PH 7.5 | | Descriptor: | 34 kDa membrane antigen, COBALT (II) ION, SULFATE ION, ... | | Authors: | Brautigam, C.A., Deka, R.K., Tomchick, D.R., Machius, M., Norgard, M.V. | | Deposit date: | 2010-11-10 | | Release date: | 2011-11-02 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Characterization of the Tp34 lipoprotein from Treponema pallidum suggests a role in transition metal homeostasis
To be Published
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3PJN | | THE CRYSTAL STRUCTURE OF TP34 BOUND TO ZN(II) ION AT PH 7.5 | | Descriptor: | 34 kDa membrane antigen, ZINC ION, SULFATE ION, ... | | Authors: | Brautigam, C.A., Deka, R.K., Tomchick, D.R., Machius, M., Norgard, M.V. | | Deposit date: | 2010-11-10 | | Release date: | 2011-11-02 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Characterization of the Tp34 lipoprotein from Treponema pallidum suggests a role in transition metal homeostasis
To be Published
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3RNM | | THE CRYSTAL STRUCTURE OF THE SUBUNIT BINDING OF HUMAN DIHYDROLIPOAMIDE TRANSACYLASE (E2B) BOUND TO HUMAN DIHYDROLIPOAMIDE DEHYDROGENASE (E3) | | Descriptor: | Dihydrolipoyl dehydrogenase, mitochondrial, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, ... | | Authors: | Brautigam, C.A., Wynn, R.M., Chuang, J.C., Young, B.B., Chuang, D.T. | | Deposit date: | 2011-04-22 | | Release date: | 2011-05-04 | | Last modified: | 2011-07-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and Thermodynamic Basis for Weak Interactions between Dihydrolipoamide Dehydrogenase and Subunit-binding Domain of the Branched-chain {alpha}-Ketoacid Dehydrogenase Complex.
J.Biol.Chem., 286, 2011
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4DI3 | |
4DI4 | | CRYSTAL STRUCTURE OF A 3:1 COMPLEX OF TREPONEMA PALLIDUM TATP(T) (TP0957) BOUND TO TATT (TP0956) | | Descriptor: | TatT (Tp0956), TatP(T) (Tp0957), TRIETHYLENE GLYCOL, ... | | Authors: | Brautigam, C.A., Deka, R.K., Norgard, M.V. | | Deposit date: | 2012-01-30 | | Release date: | 2012-05-23 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.714 Å) | | Cite: | Structural and Thermodynamic Characterization of the Interaction between Two Periplasmic Treponema pallidum Lipoproteins that are Components of a TPR-Protein-Associated TRAP Transporter (TPAT).
J.Mol.Biol., 420, 2012
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4N13 | | CRYSTAL STRUCTURE OF PSTS (BB_0215) FROM BORRELIA BURGDORFERI | | Descriptor: | Phosphate ABC transporter, periplasmic phosphate-binding protein, SULFATE ION, ... | | Authors: | Brautigam, C.A., Deka, R.K., Norgard, M.V. | | Deposit date: | 2013-10-03 | | Release date: | 2014-01-22 | | Last modified: | 2014-02-12 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Sequence, biophysical, and structural analyses of the PstS lipoprotein (BB0215) from Borrelia burgdorferi reveal a likely binding component of an ABC-type phosphate transporter.
Protein Sci., 23, 2014
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5JX2 | | CRYSTAL STRUCTURE OF MGLB-2 (TP0684) FROM TREPONEMA PALLIDUM | | Descriptor: | Glucose/galactose-binding lipoprotein, CALCIUM ION, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | Authors: | Brautigam, C.A., Deka, R.K., Norgard, M.V. | | Deposit date: | 2016-05-12 | | Release date: | 2016-08-31 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.0504 Å) | | Cite: | The Tp0684 (MglB-2) Lipoprotein of Treponema pallidum: A Glucose-Binding Protein with Divergent Topology.
Plos One, 11, 2016
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5U2P | | THE CRYSTAL STRUCTURE OF TP0737 FROM TREPONEMA PALLIDUM | | Descriptor: | Sugar ABC transporter substrate-binding protein, BROMIDE ION, CHLORIDE ION, ... | | Authors: | Brautigam, C.A., Deka, R.K., Tomchick, D.R., Norgard, M.V. | | Deposit date: | 2016-11-30 | | Release date: | 2017-02-22 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein from Treponema pallidum.
Protein Sci., 26, 2017
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