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A NEW PARADIGM FOR TUMOR NECROSIS FACTOR SIGNALLING
Descriptor:	TUMOR NECROSIS FACTOR RECEPTOR
Authors:	Naismith, J.H, Sprang, S.R.
Deposit date:	1994-10-12
Release date:	1995-12-07
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor. J.Biol.Chem., 270, 1995

Crystal structure of the BRAF:MEK1 complex
Descriptor:	7-fluoro-3-[(2-fluoro-4-iodophenyl)amino]-N-{[(2S)-2-hydroxypropyl]oxy}furo[3,2-c]pyridine-2-carboxamide, CHLORIDE ION, Dual specificity mitogen-activated protein kinase kinase 1, ...
Authors:	Sudhamsu, J, Haling, J.R, Morales, T, Brandhuber, B, Hymowitz, S.G.
Deposit date:	2013-09-10
Release date:	2014-06-18
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.8483 Å)
Cite:	Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling. Cancer Cell, 26, 2014

Crystal structure of BRAF-V600E bound to GDC0879
Descriptor:	2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol, CHLORIDE ION, Serine/threonine-protein kinase B-raf
Authors:	Sudhamsu, J, Haling, J.R, Morales, T, Brandhuber, B, Hymowitz, S.G.
Deposit date:	2013-09-10
Release date:	2014-06-18
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.802 Å)
Cite:	Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling. Cancer Cell, 26, 2014

EXTRACELLULAR DOMAIN OF THE 55KDA TUMOR NECROSIS FACTOR RECEPTOR. CRYSTALLIZED AT PH3.7 IN P 21 21 21.
Descriptor:	MAGNESIUM ION, SULFATE ION, TUMOR NECROSIS FACTOR RECEPTOR
Authors:	Naismith, J.H, Sprang, S.R.
Deposit date:	1996-07-03
Release date:	1997-01-11
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Structures of the extracellular domain of the type I tumor necrosis factor receptor. Structure, 4, 1996