Author results

5CQ3
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH 6-HYDROXYPICOLINIC ACID (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, 6-hydroxypyridine-2-carboxylic acid, ...
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-21
Release date:2015-09-09
Method:X-RAY DIFFRACTION (1.925 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 6-Hydroxypicolinic acid (SGC - Diamond I04-1 fragment screening)
To be published
5CQ4
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH 3'-HYDROXYACETOPHENONE (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, 1-(3-hydroxyphenyl)ethanone, ...
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-21
Release date:2015-09-09
Method:X-RAY DIFFRACTION (1.782 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 3'-Hydroxyacetophenone (SGC - Diamond I04-1 fragment screening)
To be published
5CQ5
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH 2,3-ETHYLENEDIOXYBENZOIC ACID (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, 2,3-dihydro-1,4-benzodioxine-5-carboxylic acid
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-21
Release date:2015-09-09
Method:X-RAY DIFFRACTION (1.961 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 2,3-Ethylenedioxybenzoic Acid (SGC - Diamond I04-1 fragment screening)
To be published
5CQ6
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH 2,6-PYRIDINEDICARBOXYLIC ACID (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, PYRIDINE-2,6-DICARBOXYLIC ACID
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-21
Release date:2015-09-09
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 2,6-Pyridinedicarboxylic acid (SGC - Diamond I04-1 fragment screening)
To be published
5CQ7
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH N,N-DIMETHYLQUINOXALINE-6-CARBOXAMIDE (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, N,N-dimethylquinoxaline-6-carboxamide, 1,2-ETHANEDIOL
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-21
Release date:2015-09-09
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with N,N-dimethylquinoxaline-6-carboxamide (SGC - Diamond I04-1 fragment screening)
To be published
5CQ8
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH 4'-HYDROXYACETOPHENONE (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, P-HYDROXYACETOPHENONE
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-21
Release date:2015-09-09
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 4'-Hydroxyacetophenone (SGC - Diamond I04-1 fragment screening)
To be published
5CQA
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH N-METHYL-2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXINE-5-CARBOXAMIDE (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, N-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide, 1,2-ETHANEDIOL
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-21
Release date:2015-09-09
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with N-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide (SGC - Diamond I04-1 fragment screening)
To be published
5CU8
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH 2-AMINO-6-CHLOROBENZOTHIAZOLE (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, 6-chloro-1,3-benzothiazol-2-amine, 1,2-ETHANEDIOL
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-24
Release date:2015-09-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 2-Amino-6-chlorobenzothiazole (SGC - Diamond I04-1 fragment screening)
To be published
5CUA
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH 1-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, 1-[4-(4-hydroxyphenyl)piperazin-1-yl]ethanone
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-24
Release date:2015-09-09
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 1-Acetyl-4-(4-hydroxyphenyl)piperazine (SGC - Diamond I04-1 fragment screening)
To be published
5CUB
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH 314268-40-1 (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, methyl 4-[(4-methylpiperazin-1-yl)methyl]benzoate, 1,2-ETHANEDIOL
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-24
Release date:2015-09-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 314268-40-1 (SGC - Diamond I04-1 fragment screening)
To be published
5CUC
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH N-ACETYL-2-PHENYLETHYLAMINE (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, N-(2-phenylethyl)acetamide, 1,2-ETHANEDIOL
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-24
Release date:2015-09-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with N-Acetyl-2-phenylethylamine (SGC - Diamond I04-1 fragment screening)
To be published
5CUD
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH 6-CHLOROPURINE (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, 6-chloro-9H-purine
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-24
Release date:2015-09-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 6-CHLOROPURINE (SGC - Diamond I04-1 fragment screening)
To be published
5CUE
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH AGN-PC-04G0SS (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, 5-chloro-N,1-dimethyl-1H-pyrazole-4-carboxamide, 1,2-ETHANEDIOL
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-24
Release date:2015-09-09
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with AGN-PC-04G0SS (SGC - Diamond I04-1 fragment screening)
To be published
5CUG
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B (BAZ2B) IN COMPLEX WITH 4-ACETAMIDOBENZOIC ACID (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:Bromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, PARA ACETAMIDO BENZOIC ACID
Authors:Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2015-07-24
Release date:2015-09-09
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 4-Acetamidobenzoic acid (SGC - Diamond I04-1 fragment screening)
To be published
4BKP
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CRYSTAL STRUCTURE OF HUMAN GDP-L-FUCOSE SYNTHASE WITH BOUND NADP
Descriptor:GDP-L-FUCOSE SYNTHASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRATE ANION, ...
Authors:Vollmar, M., Shafqat, N., Rojkova, A., Krojer, T., Bradley, A., Raynor, J.W., Kavanagh, K., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U., Yue, W.W.
Deposit date:2013-04-29
Release date:2013-06-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Human Gdp-L-Fucose Synthase with Bound Nadp
To be Published
4BL5
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CRYSTAL STRUCTURE OF HUMAN GDP-L-FUCOSE SYNTHASE WITH BOUND NADP AND PRODUCT GDP-L-FUCOSE
Descriptor:GDP-L-FUCOSE SYNTHASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, ...
Authors:Vollmar, M., Shafqat, N., Rojkova, A., Krojer, T., Bradley, A., Raynor, J.W., Kavanagh, K., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U., Yue, W.W.
Deposit date:2013-05-01
Release date:2014-05-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Human Gdp-L-Fucose Synthase with Bound Nadp and Product Gdp-L-Fucose
To be Published
4D6Q
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CRYSTAL STRUCTURE OF HUMAN JMJD2D IN COMPLEX WITH 2,4-PDCA
Descriptor:LYSINE-SPECIFIC DEMETHYLASE 4D, ZINC ION, NICKEL (II) ION, ...
Authors:Krojer, T., Vollmar, M., Bradley, A., Crawley, L., Szykowska, A., Burgess-Brown, N., Gileadi, C., Johansson, C., Oppermann, U., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
Deposit date:2014-11-14
Release date:2014-12-24
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.292 Å)
Cite:Crystal Structure of Human Jmjd2D in Complex with 2,4-Pdca
To be Published
4D6R
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CRYSTAL STRUCTURE OF HUMAN JMJD2D IN COMPLEX WITH N-OXALYLGLYCINE AND BOUND O-TOLUENESULFONAMIDE
Descriptor:LYSINE-SPECIFIC DEMETHYLASE 4D, ZINC ION, NICKEL (II) ION, ...
Authors:Krojer, T., Vollmar, M., Bradley, A., Crawley, L., Szykowska, A., Burgess-Brown, N., Gileadi, C., Johansson, C., Oppermann, U., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
Deposit date:2014-11-14
Release date:2014-12-24
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.398 Å)
Cite:Crystal Structure of Human Jmjd2D in Complex with N-Oxalylglycine and Bound O-Toluenesulfonamide
To be Published
4D6S
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CRYSTAL STRUCTURE OF HUMAN JMJD2D IN COMPLEX WITH N-OXALYLGLYCINE AND BOUND 5,6-DIMETHYLBENZIMIDAZOLE
Descriptor:LYSINE-SPECIFIC DEMETHYLASE 4D, ZINC ION, NICKEL (II) ION, ...
Authors:Krojer, T., Vollmar, M., Bradley, A., Crawley, L., Szykowska, A., Burgess-Brown, N., Gileadi, C., Johansson, C., Oppermann, U., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
Deposit date:2014-11-14
Release date:2014-12-24
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of Human Jmjd2D in Complex with N-Oxalylglycine and Bound 5,6- Dimethylbenzimidazole
To be Published
4UYI
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CRYSTAL STRUCTURE OF THE BTB DOMAIN OF HUMAN SLX4 (BTBD12)
Descriptor:STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4
Authors:Pinkas, D.M., Sanvitale, C.E., Strain-Damerell, C., Fairhead, M., Wang, D., Tallant, C., Cooper, C.D.O., Sorrell, F.J., Kopec, J., Chaikuad, A., Fitzpatrick, F., Pike, A.C.W., Hozjan, V., Ying, Z., Roos, A.K., Savitsky, P., Bradley, A., Nowak, R., Filippakopoulos, P., Krojer, T., Burgess-Brown, N.A., Marsden, B.D., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.
Deposit date:2014-09-01
Release date:2014-10-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal Structure of the Btb Domain of Human Slx4 (Btbd12)
To be Published
3ZOS
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STRUCTURE OF THE DDR1 KINASE DOMAIN IN COMPLEX WITH PONATINIB
Descriptor:EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1, 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide, 1,2-ETHANEDIOL
Authors:Canning, P., Elkins, J.M., Goubin, S., Mahajan, P., Bradley, A., Coutandin, D., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.
Deposit date:2013-02-22
Release date:2013-05-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural Mechanisms Determining Inhibition of the Collagen Receptor Ddr1 by Selective and Multi-Targeted Type II Kinase Inhibitors
J.Mol.Biol., 426, 2014
4C02
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CRYSTAL STRUCTURE OF HUMAN ACVR1 (ALK2) IN COMPLEX WITH FKBP12.6 AND DORSOMORPHIN
Descriptor:ACTIVIN RECEPTOR TYPE-1, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1B, CITRATE ANION, ...
Authors:Williams, E., Riesebos, E., Vollmar, M., Krojer, T., Bradley, A., Shrestha, L., Kupinska, K., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.
Deposit date:2013-07-31
Release date:2013-08-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Crystal Structure of Human Acvr1 (Alk2) in Complex with Fkbp12.6 And Dorsomorphin
Ph D Thesis
4MX2
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CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM LEISHMANIA DONOVANI
Descriptor:Adenylosuccinate lyase, ADENOSINE MONOPHOSPHATE, SULFATE ION, ...
Authors:Wernimont, A.K., Loppnau, P., Dong, A., Krojer, T., Bradley, A., Bushell, S., von Delft, F., Robinson, D., Gilbert, I., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Hui, R., Mottaghi, K., Structural Genomics Consortium (SGC)
Deposit date:2013-09-25
Release date:2014-04-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of adenylosuccinate lyase from Leishmania donovani
To be Published
5AME
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN SURFACE EPITOPE ENGINEERED BRD1A IN COMPLEX WITH 3D CONSORTIUM FRAGMENT 4-ACETYL- PIPERAZIN-2-ONE (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:BROMODOMAIN-CONTAINING PROTEIN 1, 4-acetyl-piperazin-2-one, SODIUM ION
Authors:Pearce, N.M., Fairhead, M., Strain-Damerell, C., Talon, R., Wright, N., Ng, J.T., Bradley, A., Cox, O., Bowkett, D., Collins, P., Brandao-Neto, J., Douangamath, A., Krojer, T., Burgess-Brown, N., Brennan, P., Arrowsmith, C.H., Edwards, E., Bountra, C., von Delft, F.
Deposit date:2015-03-10
Release date:2015-03-18
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.578 Å)
Cite:Crystal Structure of the Bromodomain of Human Surface Epitope Engineered Brd1A in Complex with 3D Consortium Fragment 4-Acetyl-Piperazin-2-One
To be Published
5AMF
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN SURFACE EPITOPE ENGINEERED BRD1A IN COMPLEX WITH 3D CONSORTIUM FRAGMENT ETHYL 4,5,6,7- TETRAHYDRO-1H-INDAZOLE-5-CARBOXYLATE (SGC - DIAMOND I04-1 FRAGMENT SCREENING)
Descriptor:BROMODOMAIN-CONTAINING PROTEIN 1, ETHYL (5R)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE-5-CARBOXYLATE, SODIUM ION
Authors:Pearce, N.M., Fairhead, M., Strain-Damerell, C., Talon, R., Wright, N., Ng, J.T., Bradley, A., Cox, O., Bowkett, D., Collins, P., Brandao-Neto, J., Douangamath, A., Krojer, T., Burgess-Brown, N., Brennan, P., Arrowsmith, C.H., Edwards, E., Bountra, C., von Delft, F.
Deposit date:2015-03-10
Release date:2015-03-18
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of the Bromodomain of Human Surface Epitope Engineered Brd1A in Complex with 3D Consortium Fragment Ethyl 4,5,6,7-Tetrahydro-1H-Indazole-5-Carboxylate
To be Published
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