4B7I
 
 | | Crystal Structure of Human IgG Fc Bearing Hybrid-type Glycans | | Descriptor: | CHLORIDE ION, IG GAMMA-1 CHAIN C REGION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Bowden, T.A, Baruah, K, Coles, C.H, Harvey, D.J, Song, B.D, Stuart, D.I, Aricescu, A.R, Scanlan, C.N, Jones, E.Y, Crispin, M. | | Deposit date: | 2012-08-20 | | Release date: | 2012-10-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped During Glycan Biosynthesis.
J.Am.Chem.Soc., 134, 2012
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2VWD
 | | Nipah Virus Attachment Glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GAMMA-BUTYROLACTONE, ... | | Authors: | Bowden, T.A, Crispin, M, Harvey, D.J, Aricescu, A.R, Grimes, J.M, Jones, E.Y, Stuart, D.I. | | Deposit date: | 2008-06-20 | | Release date: | 2008-10-07 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystal Structure and Carbohydrate Analysis of Nipah Virus Attachment Glycoprotein: A Template for Antiviral and Vaccine Design.
J.Virol., 82, 2008
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2WFO
 | | Crystal structure of Machupo virus envelope glycoprotein GP1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCOPROTEIN 1 | | Authors: | Bowden, T.A, Crispin, M, Graham, S.C, Harvey, D.J, Grimes, J.M, Jones, E.Y, Stuart, D.I. | | Deposit date: | 2009-04-09 | | Release date: | 2009-06-16 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Unusual Molecular Architecture of the Machupo Virus Attachment Glycoprotein.
J.Virol., 83, 2009
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2WO1
 | | Crystal Structure of the EphA4 Ligand Binding Domain | | Descriptor: | EPHRIN TYPE-A RECEPTOR, N-PROPANOL | | Authors: | Bowden, T.A, Aricescu, A.R, Nettleship, J.E, Siebold, C, Rahman-Huq, N, Owens, R.J, Stuart, D.I, Jones, E.Y. | | Deposit date: | 2009-07-21 | | Release date: | 2009-10-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural Plasticity of Eph-Receptor A4 Facilitates Cross-Class Ephrin Signalling
Structure, 17, 2009
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2WO2
 | | Crystal Structure of the EphA4-ephrinB2 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EPHRIN TYPE-A RECEPTOR, EPHRIN-B2 | | Authors: | Bowden, T.A, Aricescu, A.R, Nettleship, J.E, Siebold, C, Rahman-Huq, N, Owens, R.J, Stuart, D.I, Jones, E.Y. | | Deposit date: | 2009-07-21 | | Release date: | 2009-10-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural Plasticity of Eph-Receptor A4 Facilitates Cross-Class Ephrin Signalling
Structure, 17, 2009
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2WO3
 | | Crystal Structure of the EphA4-ephrinA2 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPHRIN TYPE-A RECEPTOR, EPHRIN-A2 | | Authors: | Bowden, T.A, Aricescu, A.R, Nettleship, J.E, Siebold, C, Rahman-Huq, N, Owens, R.J, Stuart, D.I, Jones, E.Y. | | Deposit date: | 2009-07-21 | | Release date: | 2009-10-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural Plasticity of Eph-Receptor A4 Facilitates Cross-Class Ephrin Signalling
Structure, 17, 2009
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2X9M
 | | Hendra virus attachment glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCOPROTEIN G | | Authors: | Bowden, T.A, Crispin, M, Harvey, D, Jones, E.Y, Stuart, D.I. | | Deposit date: | 2010-03-23 | | Release date: | 2010-04-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Dimeric Architecture of the Hendra Virus Attachment Glycoprotein: Evidence for a Conserved Mode of Assembly.
J.Virol., 84, 2010
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2VSM
 | | Nipah virus attachment glycoprotein in complex with human cell surface receptor ephrinB2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EPHRIN-B2, HEMAGGLUTININ-NEURAMINIDASE, ... | | Authors: | Bowden, T.A, Aricescu, A.R, Gilbert, R.J, Grimes, J.M, Jones, E.Y, Stuart, D.I. | | Deposit date: | 2008-04-25 | | Release date: | 2008-05-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis of Nipah and Hendra Virus Attachment to Their Cell-Surface Receptor Ephrin-B2
Nat.Struct.Mol.Biol., 15, 2008
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2VSK
 | | Hendra virus attachment glycoprotein in complex with human cell surface receptor ephrinB2 | | Descriptor: | EPHRIN-B2, HEMAGGLUTININ-NEURAMINIDASE | | Authors: | Bowden, T.A, Aricescu, A.R, Gilbert, R.J, Grimes, J.M, Jones, E.Y, Stuart, D.I. | | Deposit date: | 2008-04-24 | | Release date: | 2008-05-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural Basis of Nipah and Hendra Virus Attachment to Their Cell-Surface Receptor Ephrin-B2
Nat.Struct.Mol.Biol., 15, 2008
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6SG8
 | | Structure of Sosuga virus receptor binding protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | | Authors: | Bowden, T.A, Stelfox, A.J. | | Deposit date: | 2019-08-02 | | Release date: | 2019-10-09 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A structure-based rationale for sialic acid independent host-cell entry of Sosuga virus.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5OPG
 | | Structure of the Hantaan virus Gn glycoprotein ectodomain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... | | Authors: | Rissanen, I, Stass, R, Zeltina, A, Li, S, Hepojoki, J, Harlos, K, Gilbert, R.J.C, Huiskonen, J.T, Bowden, T.A. | | Deposit date: | 2017-08-09 | | Release date: | 2017-08-23 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope.
J. Virol., 91, 2017
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7QU1
 | | Machupo virus GP1 glycoprotein in complex with Fab fragment of antibody MAC1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab MAC1 heavy chain, Fab MAC1 light chain, ... | | Authors: | Ng, W.M, Sahin, M, Krumm, S.A, Seow, J, Zeltina, A, Harlos, K, Paesen, G, Pinschewer, D.D, Doores, K.J, Bowden, T.A. | | Deposit date: | 2022-01-17 | | Release date: | 2022-02-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies.
Mbio, 13, 2022
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7QU2
 | | Junin virus GP1 glycoprotein in complex with Fab fragment of antibody JUN1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab JUN1 heavy chain, ... | | Authors: | Ng, W.M, Sahin, M, Krumm, S.A, Seow, J, Zeltina, A, Harlos, K, Paesen, G, Pinschewer, D.D, Doores, K.J, Bowden, T.A. | | Deposit date: | 2022-01-17 | | Release date: | 2022-02-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies.
Mbio, 13, 2022
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8AHN
 | | Sin Nombre virus Gn in complex with Fab SNV-42 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ... | | Authors: | Stass, R, Bowden, T.A. | | Deposit date: | 2022-07-22 | | Release date: | 2023-05-24 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody.
Nat Microbiol, 8, 2023
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4UF7
 | | Ghanaian henipavirus (Gh-M74a) attachment glycoprotein in complex with human ephrinB2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... | | Authors: | Lee, B, Pernet, O, Ahmed, A.A, Zeltina, A, Beaty, S.M, Bowden, T.A. | | Deposit date: | 2015-03-13 | | Release date: | 2015-04-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Molecular Recognition of Human Ephrinb2 Cell Surface Receptor by an Emergent African Henipavirus.
Proc.Natl.Acad.Sci.USA, 112, 2015
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8AWM
 | | RVFV GnH with Fab268 bound | | Descriptor: | Glycoprotein, Heavy chain Fab268, Light chain Fab268 | | Authors: | Hulswit, R.J.G, Bowden, T.A, Stass, R. | | Deposit date: | 2022-08-30 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses.
Nat Commun, 14, 2023
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8AWL
 | | Fab RVFV-268 | | Descriptor: | CITRIC ACID, Heavy chain Fab268, Light chain Fab268 | | Authors: | Hulswit, R.J.G, Bowden, T.A, Stass, R. | | Deposit date: | 2022-08-30 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses.
Nat Commun, 14, 2023
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4ACP
 | | Deactivation of human IgG1 Fc by endoglycosidase treatment | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG GAMMA-1 CHAIN C REGION | | Authors: | Raman, K, Bowden, T.A, Krishna, B.A, Dwek, R.A, Crispin, M, Scanlan, C.N. | | Deposit date: | 2011-12-16 | | Release date: | 2012-04-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Selective Deactivation of Serum Igg: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions.
J.Mol.Biol., 420, 2012
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6HJ6
 | | Crystal structure of Loei River virus GP1 glycoprotein at pH 5.0 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Pre-glycoprotein polyprotein GP complex | | Authors: | Pryce, R, Ng, W.M, Zeltina, A, Watanabe, Y, El Omari, K, Wagner, A, Bowden, T.A. | | Deposit date: | 2018-08-31 | | Release date: | 2018-10-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structure-Based Classification Defines the Discrete Conformational Classes Adopted by the Arenaviral GP1.
J. Virol., 93, 2019
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6I9I
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5NOP
 | | Structure of Mojiang virus attachment glycoprotein | | Descriptor: | Attachment glycoprotein, CHLORIDE ION | | Authors: | Rissanen, I.R, Ahmed, A.A, Beaty, S, Azarm, K, Hong, P, Nambulli, S, Duprex, P.W, Lee, B, Bowden, T.A. | | Deposit date: | 2017-04-12 | | Release date: | 2017-07-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Idiosyncratic Mojiang virus attachment glycoprotein directs a host-cell entry pathway distinct from genetically related henipaviruses.
Nat Commun, 8, 2017
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5NUZ
 | | Junin virus GP1 glycoprotein in complex with an antibody Fab fragment | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ISOPROPYL ALCOHOL, ... | | Authors: | Zeltina, A, Krumm, S.A, Sahin, M, Struwe, W.B, Harlos, K, Nunberg, J.H, Crispin, M, Pinschewer, D.D, Doores, K.J, Bowden, T.A. | | Deposit date: | 2017-05-03 | | Release date: | 2017-06-28 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7ZM5
 | | Structure of Mossman virus receptor binding protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein | | Authors: | Stelfox, A.J, Bowden, T.A, Rissanen, I, Harlos, K. | | Deposit date: | 2022-04-19 | | Release date: | 2023-09-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Crystal structure and solution state of the C-terminal head region of the narmovirus receptor binding protein.
Mbio, 14, 2023
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7ZM6
 | | Nariva virus receptor binding protein | | Descriptor: | Attachment protein | | Authors: | Stelfox, A.J, Rissanen, I, Rambo, R, Lee, B, Bowden, T.A. | | Deposit date: | 2022-04-19 | | Release date: | 2023-09-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Crystal structure and solution state of the C-terminal head region of the narmovirus receptor binding protein.
Mbio, 14, 2023
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8A1E
 | | Rabies virus glycoprotein in complex with Fab fragments of 17C7 and 1112-1 neutralizing antibodies | | Descriptor: | Fab 1112-1 heavy chain variable domain, Fab 1112-1 light chain variable domain, Fab 17C7 heavy chain variable domain, ... | | Authors: | Ng, W.M, Fedosyuk, S, English, S, Augusto, G, Berg, A, Thorley, L, Haselon, A.S, Segireddy, R.R, Bowden, T.A, Douglas, A.D. | | Deposit date: | 2022-06-01 | | Release date: | 2022-08-17 | | Last modified: | 2022-09-28 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies.
Cell Host Microbe, 30, 2022
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