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4WOT
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ROCK2 IN COMPLEX WITH 1426382-07-1
Descriptor: Rho-associated protein kinase 2, methyl 3-[({2'-(aminomethyl)-5'-[(3-fluoropyridin-4-yl)carbamoyl]biphenyl-3-yl}carbonyl)amino]-4-fluorobenzoate
Authors:Augustin, M, Krapp, S, Boland, S, Defert, O, Bourin, A, Alen, J, Leysen, D.
Deposit date:2014-10-16
Release date:2015-05-06
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Design, synthesis, and biological evaluation of novel, highly active soft ROCK inhibitors.
J. Med. Chem., 58, 2015

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