Author results

1HV2
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SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE
Descriptor:ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR
Authors:Botuyan, M.V., Mer, G., Yi, G.-S., Koth, C.M., Case, D.A., Edwards, A.M., Chazin, W.J., Arrowsmith, C.H.
Deposit date:2001-01-05
Release date:2001-09-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide.
J.Mol.Biol., 312, 2001
1CUR
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REDUCED RUSTICYANIN, NMR
Descriptor:CU(I) RUSTICYANIN, COPPER (II) ION
Authors:Botuyan, M.V., Dyson, H.J.
Deposit date:1996-04-19
Release date:1996-11-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of Cu(I) rusticyanin from Thiobacillus ferrooxidans: structural basis for the extreme acid stability and redox potential.
J.Mol.Biol., 263, 1996
6CO2
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STRUCTURE OF AN ENGINEERED PROTEIN (NUDT16TI) IN COMPLEX WITH 53BP1 TUDOR DOMAINS
Descriptor:NUDT16-Tudor-interacting (NUDT16TI), TP53-binding protein 1
Authors:Botuyan, M.V., Thompson, J.R., Cui, G., Mer, G.
Deposit date:2018-03-10
Release date:2018-06-06
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Nat. Struct. Mol. Biol., 25, 2018
2FHD
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CRYSTAL STRUCTURE OF CRB2 TANDEM TUDOR DOMAINS
Descriptor:DNA repair protein rhp9/CRB2, PHOSPHATE ION
Authors:Lee, J., Botuyan, M.V., Thompson, J.R., Mer, G.
Deposit date:2005-12-23
Release date:2007-01-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.
Cell(Cambridge,Mass.), 127, 2006
2G3R
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CRYSTAL STRUCTURE OF 53BP1 TANDEM TUDOR DOMAINS AT 1.2 A RESOLUTION
Descriptor:Tumor suppressor p53-binding protein 1, SULFATE ION
Authors:Lee, J., Botuyan, M.V., Thompson, J.R., Mer, G.
Deposit date:2006-02-20
Release date:2007-01-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair.
Cell(Cambridge,Mass.), 127, 2006
6CO1
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STRUCTURE OF HUMAN TIRR IN COMPLEX WITH 53BP1 TUDOR DOMAINS
Descriptor:Tudor-interacting repair regulator protein, TP53-binding protein 1
Authors:Cui, G., Botuyan, M.V., Mer, G.
Deposit date:2018-03-10
Release date:2018-06-06
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.179 Å)
Cite:Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Nat. Struct. Mol. Biol., 25, 2018
6D0L
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STRUCTURE OF HUMAN TIRR
Descriptor:Tudor-interacting repair regulator protein
Authors:Cui, G., Botuyan, M.V., Mer, G.
Deposit date:2018-04-10
Release date:2018-06-06
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Nat. Struct. Mol. Biol., 25, 2018
2B02
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CRYSTAL STRUCTURE OF ARNT PAS-B DOMAIN
Descriptor:Aryl hydrocarbon receptor nuclear translocator
Authors:Lee, J., Botuyan, M.V., Nomine, Y., Ohh, M., Thompson, J.R., Mer, G.
Deposit date:2005-09-12
Release date:2006-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure and Binding Properties of ARNT PAS-B Heterodimerization Domain
To be Published
2MWO
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SOLUTION STRUCTURE OF 53BP1 TANDEM TUDOR DOMAINS IN COMPLEX WITH A P53K370ME2 PEPTIDE
Descriptor:Tumor suppressor p53-binding protein 1, Cellular tumor antigen p53
Authors:Cui, G., Botuyan, M.V., Mer, G.
Deposit date:2014-11-15
Release date:2014-12-10
Last modified:2015-03-18
Method:SOLUTION NMR
Cite:Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1.
Structure, 23, 2015
2MWP
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SOLUTION STRUCTURE OF 53BP1 TANDEM TUDOR DOMAINS IN COMPLEX WITH A P53K382ME2 PEPTIDE
Descriptor:Tumor suppressor p53-binding protein 1, Cellular tumor antigen p53
Authors:Cui, G., Botuyan, M.V., Mer, G.
Deposit date:2014-11-15
Release date:2014-12-10
Last modified:2015-03-18
Method:SOLUTION NMR
Cite:Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1.
Structure, 23, 2015
2QQR
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JMJD2A HYBRID TUDOR DOMAINS
Descriptor:JmjC domain-containing histone demethylation protein 3A, SULFATE ION
Authors:Lee, J., Botuyan, M.V., Mer, G.
Deposit date:2007-07-26
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
2QQS
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JMJD2A TANDEM TUDOR DOMAINS IN COMPLEX WITH A TRIMETHYLATED HISTONE H4-K20 PEPTIDE
Descriptor:JmjC domain-containing histone demethylation protein 3A, METHYLATED HISTONE H4 PEPTIDE
Authors:Lee, J., Botuyan, M.V., Mer, G.
Deposit date:2007-07-26
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
3P8D
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CRYSTAL STRUCTURE OF THE SECOND TUDOR DOMAIN OF HUMAN PHF20 (HOMODIMER FORM)
Descriptor:Medulloblastoma antigen MU-MB-50.72
Authors:Cui, G., Lee, J., Thompson, J.R., Botuyan, M.V., Mer, G.
Deposit date:2010-10-13
Release date:2011-06-22
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
Nat.Struct.Mol.Biol., 19, 2012
3SD4
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CRYSTAL STRUCTURE OF THE FIRST TUDOR DOMAIN OF HUMAN PHF20
Descriptor:PHD finger protein 20
Authors:Cui, G., Botuyan, M.V., Thompson, J.R., Mer, G.
Deposit date:2011-06-08
Release date:2011-06-22
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.928 Å)
Cite:PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
Nat.Struct.Mol.Biol., 19, 2012
5TBN
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SOLUTION NMR STRUCTURE OF PHF20 PHD DOMAIN IN COMPLEX WITH A HISTONE H3K4ME2 PEPTIDE
Descriptor:PHD finger protein 20, Histone H3.1, ZINC ION
Authors:Cui, G., Botuyan, M.V., Mer, G.
Deposit date:2016-09-12
Release date:2016-10-12
Last modified:2017-09-20
Method:SOLUTION NMR
Cite:PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation.
Cell Rep, 17, 2016
5UMR
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF HUMAN FACT COMPLEX SUBUNIT SSRP1
Descriptor:FACT complex subunit SSRP1
Authors:Su, D., Hu, Q., Thompson, J.R., Heroux, A., Botuyan, M.V., Mer, G.
Deposit date:2017-01-29
Release date:2018-01-31
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Crystal structure of N-terminal domain of human FACT complex subunit SSRP1
To Be Published
5UMS
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CRYSTAL STRUCTURE OF MIDDLE DOUBLE PH DOMAIN OF HUMAN FACT COMPLEX SUBUNIT SSRP1
Descriptor:FACT complex subunit SSRP1
Authors:Su, D., Hu, Q., Thompson, J.R., Botuyan, M.V., Mer, G.
Deposit date:2017-01-29
Release date:2018-01-31
Method:X-RAY DIFFRACTION (1.569 Å)
Cite:Crystal structure of middle double PH domain of human FACT complex subunit SSRP1
To Be Published
5UMT
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF HUMAN FACT COMPLEX SUBUNIT SPT16
Descriptor:FACT complex subunit SPT16, ethane-1,2-diol, GLYCEROL
Authors:Su, D., Hu, Q., Thompson, J.R., Botuyan, M.V., Mer, G.
Deposit date:2017-01-29
Release date:2018-01-31
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:Crystal structure of N-terminal domain of human FACT complex subunit SPT16
To Be Published
5UMU
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CRYSTAL STRUCTURE OF THE MIDDLE DOUBLE PH DOMAIN OF HUMAN FACT COMPLEX SUBUNIT SPT16
Descriptor:FACT complex subunit SPT16, FORMIC ACID, ACETATE ION
Authors:Hu, Q., Thompson, J.R., Heroux, A., Su, D., Botuyan, M.V., Mer, G.
Deposit date:2017-01-29
Release date:2018-01-31
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Crystal structure of the middle double PH domain of human FACT complex subunit SPT16
To Be Published
5UMV
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CRYSTAL STRUCTURE OF THE BRCT DOMAIN OF S. CEREVISIAE REV1
Descriptor:DNA repair protein REV1
Authors:Lee, J., Xu, C., Thompson, J.R., Botuyan, M.V., Mer, G.
Deposit date:2017-01-29
Release date:2018-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the BRCT domain of S. cerevisiae Rev1
To Be Published
5VEY
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SOLUTION NMR STRUCTURE OF HISTONE H2A-H2B MONO-UBIQUITYLATED AT H2A LYS15 IN COMPLEX WITH RNF169 (653-708)
Descriptor:Histone H2B type 1-J,Histone H2A type 1-B/E, Polyubiquitin-B, E3 ubiquitin-protein ligase RNF169
Authors:Hu, Q., Botuyan, M.V., Cui, G., Mer, G.
Deposit date:2017-04-06
Release date:2017-05-17
Last modified:2017-05-31
Method:SOLUTION NMR
Cite:Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18.
Mol. Cell, 66, 2017
5VF0
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SOLUTION NMR STRUCTURE OF HUMAN RAD18 (198-240) IN COMPLEX WITH UBIQUITIN
Descriptor:Polyubiquitin-B, E3 ubiquitin-protein ligase RAD18, ZINC ION
Authors:Hu, Q., Botuyan, M.V., Mer, G.
Deposit date:2017-04-06
Release date:2017-05-17
Last modified:2017-09-20
Method:SOLUTION NMR
Cite:Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18.
Mol. Cell, 66, 2017
5VWE
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SOLUTION NMR STRUCTURE OF THE HMG DOMAIN OF HUMAN FACT COMPLEX SUBUNIT SSRP1
Descriptor:FACT complex subunit SSRP1
Authors:Hu, Q., Botuyan, M.V., Mer, G.
Deposit date:2017-05-21
Release date:2018-05-23
Method:SOLUTION NMR
Cite:Solution NMR structure of the HMG domain of human FACT complex subunit SSRP1
To Be Published
5VX7
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SOLUTION NMR STRUCTURE OF THE BRCT DOMAIN OF S. CEREVISIAE REV1
Descriptor:DNA repair protein REV1
Authors:Xu, C., Cui, G., Botuyan, M.V., Mer, G.
Deposit date:2017-05-23
Release date:2018-01-31
Method:SOLUTION NMR
Cite:Solution NMR structure of the BRCT domain of S. cerevisiae Rev1
To Be Published
5VZM
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SOLUTION NMR STRUCTURE OF HUMAN REV1 (932-1039) IN COMPLEX WITH UBIQUITIN
Descriptor:Ubiquitin, DNA repair protein REV1
Authors:Cui, G., Botuyan, M.V., Mer, G.
Deposit date:2017-05-29
Release date:2018-05-23
Last modified:2018-07-04
Method:SOLUTION NMR
Cite:Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin.
J. Mol. Biol., 430, 2018
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