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2PC4
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BU of 2pc4 by Molmil
Crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP-tail determined at 2.4 angstrom resolution
Descriptor: Fructose-bisphosphate aldolase, PbTRAP
Authors:Bosch, J, Buscaglia, C.A, Krumm, B, Cardozo, T, Nussenzweig, V, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2007-03-29
Release date:2007-04-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QAC
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BU of 2qac by Molmil
The closed MTIP-MyosinA-tail complex from the malaria parasite invasion machinery
Descriptor: Myosin A tail domain interacting protein MTIP, Myosin-A
Authors:Bosch, J, Turley, S, Roach, C.M, Daly, T.M, Bergman, L.W, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2007-06-14
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Closed MTIP-Myosin A-Tail Complex from the Malaria Parasite Invasion Machinery.
J.Mol.Biol., 372, 2007
2F67
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BU of 2f67 by Molmil
Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.6 A resolution with BENZO[CD]INDOL-2(1H)-ONE bound
Descriptor: BENZO[CD]INDOL-2(1H)-ONE, GLYCEROL, Nucleoside 2-deoxyribosyltransferase, ...
Authors:Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-11-28
Release date:2005-12-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49, 2006
2F62
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BU of 2f62 by Molmil
Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.5 A resolution with (2-ETHYLPHENYL)METHANOL bound
Descriptor: (2-ETHYLPHENYL)METHANOL, GLYCEROL, Nucleoside 2-deoxyribosyltransferase, ...
Authors:Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-11-28
Release date:2005-12-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49, 2006
2F2T
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BU of 2f2t by Molmil
Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.7 A resolution with 5-Aminoisoquinoline bound
Descriptor: GLYCEROL, ISOQUINOLIN-5-AMINE, Nucleoside 2-deoxyribosyltransferase, ...
Authors:Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-11-17
Release date:2005-11-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49, 2006
2F64
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BU of 2f64 by Molmil
Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.6 A resolution with 1-METHYLQUINOLIN-2(1H)-ONE bound
Descriptor: 1-METHYLQUINOLIN-2(1H)-ONE, GLYCEROL, Nucleoside 2-deoxyribosyltransferase, ...
Authors:Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-11-28
Release date:2005-12-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49, 2006
2A0K
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BU of 2a0k by Molmil
Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.8 A resolution
Descriptor: GLYCEROL, Nucleoside 2-deoxyribosyltransferase, SULFATE ION
Authors:Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-06-16
Release date:2005-07-26
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49, 2006
1X6O
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BU of 1x6o by Molmil
Structural Analysis of Leishmania braziliensis eukaryotic initiation factor 5a
Descriptor: DI(HYDROXYETHYL)ETHER, eukaryotic initiation factor 5a
Authors:Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-08-11
Release date:2004-08-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Analysis of Leishmania braziliensis eukaryotic initiation factor 5a
To be Published
1XTD
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BU of 1xtd by Molmil
Structural Analysis of Leishmania mexicana eukaryotic initiation factor 5a
Descriptor: eukaryotic initiation factor 5a
Authors:Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-10-21
Release date:2004-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Analysis of Leishmania mexicana eukaryotic initiation factor 5a
To be Published
1Y13
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BU of 1y13 by Molmil
Structural Analysis of Plasmodium falciparum 6-pyruvoyl tetrahydropterin synthase (PTPS)
Descriptor: 6-pyruvoyl tetrahydropterin synthase, BIOPTERIN, ZINC ION
Authors:Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-11-17
Release date:2005-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of Plasmodium falciparum 6-pyruvoyl tetrahydropterin synthase (PTPS)
To be Published
3BWC
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BU of 3bwc by Molmil
Crystal structure of spermidine synthase from Trypanosoma cruzi in complex with SAM at 2.3 A resolution
Descriptor: BETA-MERCAPTOETHANOL, S-ADENOSYLMETHIONINE, Spermidine synthase
Authors:Bosch, J, Arakaki, T.L, Le Trong, I, Merritt, E.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2008-01-09
Release date:2008-04-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of spermidine synthase from Trypanosoma cruzi.
To be Published
3BWB
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BU of 3bwb by Molmil
Crystal structure of the apo form of spermidine synthase from Trypanosoma cruzi at 2.5 A resolution
Descriptor: Spermidine synthase
Authors:Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2008-01-08
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of spermidine synthase from Trypanosoma cruzi.
To be Published
3TGH
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BU of 3tgh by Molmil
GAP50 the anchor in the inner membrane complex of Plasmodium
Descriptor: COBALT (II) ION, DIMETHYL SULFOXIDE, Glideosome-associated protein 50, ...
Authors:Bosch, J, Paige, M.H, Vaidya, A, Bergman, L, Hol, W.G.J.
Deposit date:2011-08-17
Release date:2012-03-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum.
J.Struct.Biol., 178, 2012
2GOP
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BU of 2gop by Molmil
The beta-propeller domain of the Trilobed protease from Pyrococcus furiosus reveals an open velcro topology
Descriptor: Trilobed Protease
Authors:Bosch, J, Tamura, T, Tamura, N, Baumeister, W, Essen, L.-O.
Deposit date:2006-04-13
Release date:2007-01-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The beta-propeller domain of the trilobed protease from Pyrococcus furiosus reveals an open Velcro topology.
Acta Crystallogr.,Sect.D, 63, 2007
2A0U
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BU of 2a0u by Molmil
Crystal structure of the eukaryotic initiation factor 2B from Leishmania major at 2.1 A resolution
Descriptor: SULFATE ION, initiation factor 2B
Authors:Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-06-17
Release date:2005-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the eukaryotic initiation factor 2B from Leishmania major at 2.1 A resolution
To be Published
2A0S
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BU of 2a0s by Molmil
Crystal structure of 6-pyruvoyl tetrahydropterin synthase (PTPS) from Plasmodium vivax at 2.2 A resolution
Descriptor: 6-pyruvoyl tetrahydropterin synthase, BIOPTERIN, ZINC ION
Authors:Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-06-16
Release date:2005-07-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of 6-pyruvoyl tetrahydropterin synthase (PTPS) from Plasmodium vivax at 2.2 A resolution
To be Published
2AUC
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BU of 2auc by Molmil
Structure of the Plasmodium MTIP-MyoA complex, a key component of the parasite invasion motor
Descriptor: Myosin A, Myosin A Tail Interacting Protein
Authors:Bosch, J, Turley, S, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-08-27
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the MTIP-MyoA complex, a key component of the malaria parasite invasion motor.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2EPH
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BU of 2eph by Molmil
Crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP-tail determined at 2.7 angstrom resolution
Descriptor: Fructose-bisphosphate aldolase, PbTRAP
Authors:Bosch, J, Buscaglia, C.A, Krumm, B, Cardozo, T, Nussenzweig, V, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2007-03-30
Release date:2007-04-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4TR9
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BU of 4tr9 by Molmil
Ternary co-crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP and a small molecule inhibitor
Descriptor: ALA-ALA-ALA-SER-LEU-TYR-GLU-LYS-LYS-ALA-ALA, ALA-ALA-SER-LEU-TYR-GLU-LYS-LYS-ALA-ALA, ASP-TRP-ASN, ...
Authors:Bosch, G, Weltzer, R, O'Malley, K, Bosch, J.
Deposit date:2014-06-15
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.111 Å)
Cite:Inhibition by stabilization: targeting the Plasmodium falciparum aldolase-TRAP complex.
Malar.J., 14, 2015
4W5V
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BU of 4w5v by Molmil
Crystal structure of Human SUMO E2-conjugating enzyme (Ubc9) in complex with E1-activating enzyme (Uba2) ubiquitin fold domain (Ufd)
Descriptor: FORMIC ACID, GLYCEROL, POTASSIUM ION, ...
Authors:Boucher, L.E, Reiter, K.H, Matunis, M.J, Bosch, J.
Deposit date:2014-08-19
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human SUMO complex
To Be Published
4XDI
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BU of 4xdi by Molmil
Structure of Chlamydomonas reinhardtii THB1
Descriptor: Chlamydomonas reinhardtii THB1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Rice, S.L, Boucher, L.E, Schlessman, J.L, Bosch, J, Lecomte, J.T.J.
Deposit date:2014-12-19
Release date:2015-01-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.893 Å)
Cite:Structure of Chlamydomonas reinhardtii THB1, a group 1 truncated hemoglobin with a rare histidine-lysine heme ligation.
Acta Crystallogr.,Sect.F, 71, 2015
4TU1
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BU of 4tu1 by Molmil
Structure of Toxoplasma gondii fructose 1,6 bisphosphate aldolase
Descriptor: Fructose-1,6-bisphosphate aldolase, GLYCEROL
Authors:Boucher, L.E, Bosch, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-06-23
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Toxoplasma gondii fructose-1,6-bisphosphate aldolase.
Acta Crystallogr.,Sect.F, 70, 2014
4M1N
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BU of 4m1n by Molmil
Crystal structure of Plasmodium falciparum ubiquitin conjugating enzyme UBC9
Descriptor: SODIUM ION, Ubiquitin conjugating enzyme UBC9
Authors:Boucher, L.E, Reiter, K.H, Bosch, J, Matunis, J.M.
Deposit date:2013-08-03
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum.
J.Biol.Chem., 288, 2013
1TQX
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BU of 1tqx by Molmil
Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum
Descriptor: D-ribulose-5-phosphate 3-epimerase, putative, SULFATE ION, ...
Authors:Caruthers, J, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-06-18
Release date:2004-12-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum.
Proteins, 62, 2006
3P1W
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BU of 3p1w by Molmil
Crystal Structure of RAB GDI from Plasmodium Falciparum, PFL2060c
Descriptor: RabGDI protein
Authors:Wernimont, A.K, Neculai, A.M, Weadge, J, MacKenzie, F, Cossar, D, Tempel, W, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Langsley, G, Bosch, J, Hui, R, Pizzaro, J.C, Hutchinson, A, Structural Genomics Consortium (SGC)
Deposit date:2010-09-30
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of RAB GDI from Plasmodium Falciparum, PFL2060c
To be published

 

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