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3S7G
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BU of 3s7g by Molmil
Aglycosylated human igg1 fc fragment
Descriptor: Ig gamma-1 chain C region
Authors:Borrok, M.J, Georgiou, G.
Deposit date:2011-05-26
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Structural Analysis of an Aglycosylated Fc
To be Published
2QW1
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BU of 2qw1 by Molmil
Glucose/galactose binding protein bound to 3-O-methyl D-glucose
Descriptor: 3-O-methyl-beta-D-glucopyranose, CALCIUM ION, D-galactose-binding periplasmic protein, ...
Authors:Borrok, M.J, Kiessling, L.L, Forest, K.T.
Deposit date:2007-08-09
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based design of a periplasmic binding protein antagonist that prevents domain closure.
Acs Chem.Biol., 4, 2009
2FW0
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BU of 2fw0 by Molmil
Apo Open Form of Glucose/Galactose Binding Protein
Descriptor: CALCIUM ION, CITRIC ACID, D-galactose-binding periplasmic protein, ...
Authors:Borrok, M.J, Kiessling, L.L, Forest, K.T.
Deposit date:2006-01-31
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures.
Protein Sci., 16, 2007
2FVY
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BU of 2fvy by Molmil
High Resolution Glucose Bound Crystal Structure of GGBP
Descriptor: ACETATE ION, CALCIUM ION, CARBON DIOXIDE, ...
Authors:Borrok, M.J, Kiessling, L.L, Forest, K.T.
Deposit date:2006-01-31
Release date:2007-02-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures.
Protein Sci., 16, 2007
3GF4
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BU of 3gf4 by Molmil
Structure of UDP-galactopyranose mutase bound to UDP-glucose
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, UDP-galactopyranose mutase, URIDINE-5'-DIPHOSPHATE-GLUCOSE, ...
Authors:Gruber, T.D, Borrok, M.J, Kiessling, L.L, Forest, K.T.
Deposit date:2009-02-26
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Ligand binding and substrate discrimination by UDP-galactopyranose mutase.
J.Mol.Biol., 391, 2009
4UB0
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BU of 4ub0 by Molmil
New design for monovalent bispecific IgG through cysteine engineering of the CH1-CL interface
Descriptor: IgG1, heavy chain, light chain
Authors:Oganesyan, V.Y, Dall'Acqua, W.F.
Deposit date:2014-08-11
Release date:2015-07-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Improving target cell specificity using a novel monovalent bispecific IgG design.
Mabs, 7, 2015
7R8U
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BU of 7r8u by Molmil
LOX-1 - Structural and Functional Studies of a Receptor Implicated in Atherosclerosis
Descriptor: Antibody light chain, kappa, Antigen binding fragment, ...
Authors:Oganesyan, V, van Dyk, N.
Deposit date:2021-06-27
Release date:2022-06-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structural and functional studies of a monoclonal antibody blocking LOX-1
Commun Med, 2023
6WIB
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BU of 6wib by Molmil
Next generation monomeric IgG4 Fc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 4, ZINC ION
Authors:Oganesyan, V.Y, Shan, L, Dall'Acqua, W, van Dyk, N.
Deposit date:2020-04-09
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
6WOL
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BU of 6wol by Molmil
Next generation monomeric IgG4 Fc bound to neonatal Fc receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ...
Authors:Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F.
Deposit date:2020-04-24
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
6WNA
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BU of 6wna by Molmil
Next generation monomeric IgG4 Fc
Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Immunoglobulin heavy constant gamma 4, ...
Authors:Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F.
Deposit date:2020-04-22
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
6WMH
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BU of 6wmh by Molmil
Next generation monomeric IgG4 Fc
Descriptor: Immunoglobulin heavy constant gamma 4
Authors:Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F.
Deposit date:2020-04-21
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021

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