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3JD0
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BU of 3jd0 by Molmil
Glutamate dehydrogenase in complex with GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Glutamate dehydrogenase 1, mitochondrial
Authors:Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD4
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BU of 3jd4 by Molmil
Glutamate dehydrogenase in complex with NADH and GTP, closed conformation
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GUANOSINE-5'-TRIPHOSPHATE, Glutamate dehydrogenase 1, ...
Authors:Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD1
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BU of 3jd1 by Molmil
Glutamate dehydrogenase in complex with NADH, closed conformation
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Glutamate dehydrogenase 1, mitochondrial
Authors:Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JCZ
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BU of 3jcz by Molmil
Structure of bovine glutamate dehydrogenase in the unliganded state
Descriptor: Glutamate dehydrogenase 1, mitochondrial
Authors:Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S.
Deposit date:2016-03-27
Release date:2016-04-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD3
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BU of 3jd3 by Molmil
Glutamate dehydrogenase in complex with NADH and GTP, open conformation
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GUANOSINE-5'-TRIPHOSPHATE, Glutamate dehydrogenase 1, ...
Authors:Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD2
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BU of 3jd2 by Molmil
Glutamate dehydrogenase in complex with NADH, open conformation
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Glutamate dehydrogenase 1, mitochondrial
Authors:Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3DNL
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BU of 3dnl by Molmil
Molecular structure for the HIV-1 gp120 trimer in the b12-bound state
Descriptor: HIV-1 envelope glycoprotein gp120
Authors:Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S.
Deposit date:2008-07-02
Release date:2008-08-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
3DNO
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BU of 3dno by Molmil
Molecular structure for the HIV-1 gp120 trimer in the CD4-bound state
Descriptor: HIV-1 envelope glycoprotein gp120
Authors:Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S.
Deposit date:2008-07-02
Release date:2008-08-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
3DNN
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BU of 3dnn by Molmil
Molecular structure for the HIV-1 gp120 trimer in the unliganded state
Descriptor: HIV-1 envelope glycoprotein gp120
Authors:Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S.
Deposit date:2008-07-02
Release date:2008-08-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
4CC8
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BU of 4cc8 by Molmil
Pre-fusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy
Descriptor: GP120, GP41, MONOCLONAL ANTIBODY VRC03 FAB HEAVY CHAIN, ...
Authors:Bartesaghi, A, Merk, A, Borgnia, M.J, Milne, J.L.S, Subramaniam, S.
Deposit date:2013-10-18
Release date:2013-10-30
Last modified:2018-01-10
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Prefusion Structure of Trimeric HIV-1 Envelope Glycoprotein Determined by Cryo-Electron Microscopy.
Nat.Struct.Mol.Biol., 20, 2013
7U65
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BU of 7u65 by Molmil
Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2
Descriptor: Deoxyguanosinetriphosphate triphosphohydrolase, Inhibitor of dGTPase
Authors:Klemm, B.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U67
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BU of 7u67 by Molmil
Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 and GTP
Descriptor: Deoxyguanosinetriphosphate triphosphohydrolase, GUANOSINE-5'-TRIPHOSPHATE, Inhibitor of dGTPase, ...
Authors:Klemm, B.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U66
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BU of 7u66 by Molmil
Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 and dGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxyguanosinetriphosphate triphosphohydrolase, Inhibitor of dGTPase, ...
Authors:Klemm, B.P, Dillard, L.B, Borgnia, M.J, Schaaper, R.M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
6OF4
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BU of 6of4 by Molmil
Precursor ribosomal RNA processing complex, apo-state.
Descriptor: CLP1_P domain-containing protein, Ribonuclease
Authors:Pillon, M.C, Hsu, A.L, Krahn, J.M, Williams, J.G, Goslen, K.H, Sobhany, M, Borgnia, M.J, Stanley, R.E.
Deposit date:2019-03-28
Release date:2019-09-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex.
Nat.Struct.Mol.Biol., 26, 2019
6OO3
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BU of 6oo3 by Molmil
Cryo-EM structure of the C4-symmetric TRPV2/RTx complex in amphipol resolved to 2.9 A
Descriptor: TRPV2, resiniferatoxin
Authors:Zubcevic, L, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OT5
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BU of 6ot5 by Molmil
Structure of the TRPV3 K169A sensitized mutant in the presence of 2-APB at 3.6 A resolution
Descriptor: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 3,Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Borschel, W.F, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
Deposit date:2019-05-02
Release date:2019-05-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
6OO4
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BU of 6oo4 by Molmil
Cryo-EM structure of the C2-symmetric TRPV2/RTx complex in amphipol resolved to 3.3 A
Descriptor: TRPV2, resiniferatoxin
Authors:Zubcevic, L, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OT2
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BU of 6ot2 by Molmil
Structure of the TRPV3 K169A sensitized mutant in apo form at 4.1 A resolution
Descriptor: Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Borschel, W.F, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
Deposit date:2019-05-02
Release date:2019-05-22
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
6PKW
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BU of 6pkw by Molmil
Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C2 symmetry (pseudo C4 symmetry)
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Yin, Y, Wu, M, Hsu, A.L, Borschel, W.F, Borgnia, M.J, Lander, G.C, Lee, S.-Y.
Deposit date:2019-06-30
Release date:2019-08-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Nat Commun, 10, 2019
6PKV
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BU of 6pkv by Molmil
Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C4 symmetry
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Yin, Y, Wu, M, Hsu, A.L, Borschel, W.F, Borgnia, M.J, Lander, G.C, Lee, S.-Y.
Deposit date:2019-06-30
Release date:2019-08-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Nat Commun, 10, 2019
6PQP
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BU of 6pqp by Molmil
Cryo-EM structure of the human TRPA1 ion channel in complex with the covalent agonist BITC
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-benzylthioformamide, ...
Authors:Suo, Y, Wang, Z, Zubcevic, L, Hsu, A.L, He, Q, Borgnia, M.J, Ji, R.-R, Lee, S.-Y.
Deposit date:2019-07-09
Release date:2020-01-08
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Neuron, 105, 2020
6PKX
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BU of 6pkx by Molmil
Cryo-EM structure of the zebrafish TRPM2 channel in the presence of ADPR and Ca2+
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 2, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Yin, Y, Wu, M, Hsu, A.L, Borschel, W.F, Borgnia, M.J, Lander, G.C, Lee, S.-Y.
Deposit date:2019-06-30
Release date:2019-08-28
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Nat Commun, 10, 2019
6PQQ
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BU of 6pqq by Molmil
Cryo-EM structure of human TRPA1 C621S mutant in the apo state
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Transient receptor potential cation channel subfamily A member 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
Authors:Suo, Y, Wang, Z, Zubcevic, L, Hsu, A.L, He, Q, Borgnia, M.J, Ji, R.-R, Lee, S.-Y.
Deposit date:2019-07-09
Release date:2020-01-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Neuron, 105, 2020
6PQO
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BU of 6pqo by Molmil
Cryo-EM structure of the human TRPA1 ion channel in complex with the covalent agonist JT010
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-N-(3-methoxypropyl)acetamide, ...
Authors:Suo, Y, Wang, Z, Zubcevic, L, Hsu, A.L, He, Q, Borgnia, M.J, Ji, R.-R, Lee, S.-Y.
Deposit date:2019-07-09
Release date:2020-01-08
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Neuron, 105, 2020
6MAT
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BU of 6mat by Molmil
Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Rix7 mutant, unknown protein
Authors:Lo, Y.H, Sobhany, M, Hsu, A.L, Ford, B.L, Krahn, J.M, Borgnia, M.J, Stanley, R.E.
Deposit date:2018-08-28
Release date:2019-02-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7.
Nat Commun, 10, 2019

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