Author results

3JCZ
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STRUCTURE OF BOVINE GLUTAMATE DEHYDROGENASE IN THE UNLIGANDED STATE
Descriptor:Glutamate dehydrogenase 1, mitochondrial
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-27
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD0
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH GTP
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD1
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, CLOSED CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD2
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD3
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, OPEN CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD4
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GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, CLOSED CONFORMATION
Descriptor:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3DNL
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MOLECULAR STRUCTURE FOR THE HIV-1 GP120 TRIMER IN THE B12-BOUND STATE
Descriptor:HIV-1 envelope glycoprotein gp120
Authors:Borgnia, M.J., Liu, J., Bartesaghi, A., Sapiro, G., Subramaniam, S.
Deposit date:2008-07-02
Release date:2008-08-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
3DNN
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MOLECULAR STRUCTURE FOR THE HIV-1 GP120 TRIMER IN THE UNLIGANDED STATE
Descriptor:HIV-1 envelope glycoprotein gp120
Authors:Borgnia, M.J., Liu, J., Bartesaghi, A., Sapiro, G., Subramaniam, S.
Deposit date:2008-07-02
Release date:2008-08-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
3DNO
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MOLECULAR STRUCTURE FOR THE HIV-1 GP120 TRIMER IN THE CD4-BOUND STATE
Descriptor:HIV-1 envelope glycoprotein gp120
Authors:Borgnia, M.J., Liu, J., Bartesaghi, A., Sapiro, G., Subramaniam, S.
Deposit date:2008-07-02
Release date:2008-08-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
4CC8
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PRE-FUSION STRUCTURE OF TRIMERIC HIV-1 ENVELOPE GLYCOPROTEIN DETERMINED BY CRYO-ELECTRON MICROSCOPY
Descriptor:GP41, GP120, MONOCLONAL ANTIBODY VRC03 FAB HEAVY CHAIN, ...
Authors:Bartesaghi, A., Merk, A., Borgnia, M.J., Milne, J.L.S., Subramaniam, S.
Deposit date:2013-10-18
Release date:2013-10-30
Last modified:2018-01-10
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Prefusion Structure of Trimeric HIV-1 Envelope Glycoprotein Determined by Cryo-Electron Microscopy.
Nat.Struct.Mol.Biol., 20, 2013
6MAT
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CRYO-EM STRUCTURE OF THE ESSENTIAL RIBOSOME ASSEMBLY AAA-ATPASE RIX7
Descriptor:Rix7 mutant, unknown protein, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lo, Y.H., Sobhany, M., Hsu, A.L., Ford, B.L., Krahn, J.M., Borgnia, M.J., Stanley, R.E.
Deposit date:2018-08-28
Release date:2019-02-06
Last modified:2019-02-13
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7.
Nat Commun, 10, 2019
6NN6
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STRUCTURE OF DOT1L-H2BK120UB NUCLEOSOME COMPLEX
Descriptor:Histone H3.2, Histone H4, Histone H2A type 1, ...
Authors:Anderson, C.J., Baird, M.R., Hsu, A., Barbour, E.H., Koyama, Y., Borgnia, M.J., McGinty, R.K.
Deposit date:2019-01-14
Release date:2019-02-13
Last modified:2019-02-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase.
Cell Rep, 26, 2019
6NR2
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CRYO-EM STRUCTURE OF THE TRPM8 ION CHANNEL IN COMPLEX WITH THE MENTHOL ANALOG WS-12 AND PI(4,5)P2
Descriptor:Transient receptor potential cation channel subfamily M member 8, (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl icosa-5,8,11,14-tetraenoate, (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide
Authors:Yin, Y., Le, S.C., Hsu, A.L., Borgnia, M.J., Yang, H., Lee, S.-Y.
Deposit date:2019-01-22
Release date:2019-02-20
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.
Science, 363, 2019
6NR3
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CRYO-EM STRUCTURE OF THE TRPM8 ION CHANNEL IN COMPLEX WITH HIGH OCCUPANCY ICILIN, PI(4,5)P2, AND CALCIUM
Descriptor:Transient receptor potential cation channel subfamily M member 8, Icilin, (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl icosa-5,8,11,14-tetraenoate, ...
Authors:Yin, Y., Le, S.C., Hsu, A.L., Borgnia, M.J., Yang, H., Lee, S.-Y.
Deposit date:2019-01-22
Release date:2019-02-20
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.
Science, 363, 2019
6NR4
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CRYO-EM STRUCTURE OF THE TRPM8 ION CHANNEL WITH LOW OCCUPANCY ICILIN, PI(4,5)P2, AND CALCIUM
Descriptor:Transient receptor potential cation channel subfamily M member 8
Authors:Yin, Y., Le, S.C., Hsu, A.L., Borgnia, M.J., Yang, H., Lee, S.-Y.
Deposit date:2019-01-22
Release date:2019-02-20
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.
Science, 363, 2019
6OF2
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PRECURSOR RIBOSOMAL RNA PROCESSING COMPLEX, STATE 2.
Descriptor:Ribonuclease, CLP1_P domain-containing protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Pillon, M.C., Hsu, A.L., Krahn, J.M., Williams, J.G., Goslen, K.H., Sobhany, M., Borgnia, M.J., Stanley, R.E.
Deposit date:2019-03-28
Release date:2019-09-11
Last modified:2019-09-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex.
Nat.Struct.Mol.Biol., 26, 2019
6OF3
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PRECURSOR RIBOSOMAL RNA PROCESSING COMPLEX, STATE 1.
Descriptor:Ribonuclease, CLP1_P domain-containing protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Pillon, M.C., Hsu, A.L., Krahn, J.M., Williams, J.G., Goslen, K.H., Sobhany, M., Borgnia, M.J., Stanley, R.E.
Deposit date:2019-03-28
Release date:2019-09-11
Last modified:2019-09-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex.
Nat.Struct.Mol.Biol., 26, 2019
6OF4
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PRECURSOR RIBOSOMAL RNA PROCESSING COMPLEX, APO-STATE.
Descriptor:Ribonuclease, CLP1_P domain-containing protein
Authors:Pillon, M.C., Hsu, A.L., Krahn, J.M., Williams, J.G., Goslen, K.H., Sobhany, M., Borgnia, M.J., Stanley, R.E.
Deposit date:2019-03-28
Release date:2019-09-11
Last modified:2019-09-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex.
Nat.Struct.Mol.Biol., 26, 2019
6OO3
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CRYO-EM STRUCTURE OF THE C4-SYMMETRIC TRPV2/RTX COMPLEX IN AMPHIPOL RESOLVED TO 2.9 A
Descriptor:TRPV2, resiniferatoxin
Authors:Zubcevic, L., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OO4
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CRYO-EM STRUCTURE OF THE C2-SYMMETRIC TRPV2/RTX COMPLEX IN AMPHIPOL RESOLVED TO 3.3 A
Descriptor:TRPV2, resiniferatoxin
Authors:Zubcevic, L., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OO5
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CRYO-EM STRUCTURE OF THE C2-SYMMETRIC TRPV2/RTX COMPLEX IN AMPHIPOL RESOLVED TO 4.2 A
Descriptor:TRPV2, resiniferatoxin
Authors:Zubcevic, L., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OO7
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CRYO-EM STRUCTURE OF THE C2-SYMMETRIC TRPV2/RTX COMPLEX IN NANODISCS
Descriptor:TRPV2, resiniferatoxin
Authors:Zubcevic, L., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OT2
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STRUCTURE OF THE TRPV3 K169A SENSITIZED MUTANT IN APO FORM AT 4.1 A RESOLUTION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Borschel, W.F., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-05-02
Release date:2019-05-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
6OT5
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STRUCTURE OF THE TRPV3 K169A SENSITIZED MUTANT IN THE PRESENCE OF 2-APB AT 3.6 A RESOLUTION
Descriptor:Transient receptor potential cation channel subfamily V member 3,Transient receptor potential cation channel subfamily V member 3, 2-aminoethyl diphenylborinate
Authors:Zubcevic, L., Borschel, W.F., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-05-02
Release date:2019-05-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
6PKV
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CRYO-EM STRUCTURE OF THE ZEBRAFISH TRPM2 CHANNEL IN THE APO CONFORMATION, PROCESSED WITH C4 SYMMETRY
Descriptor:Transient receptor potential cation channel subfamily M member 2
Authors:Yin, Y., Wu, M., Hsu, A.L., Borschel, W.F., Borgnia, M.J., Lander, G.C., Lee, S.-Y.
Deposit date:2019-06-30
Release date:2019-08-28
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C4 symmetry
To Be Published
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