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2PID
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL TYROSYL-TRNA SYNTHETASE IN COMPLEX WITH AN ADENYLATE ANALOG
Descriptor:Tyrosyl-tRNA synthetase, 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE
Authors:Bonnefond, L., Frugier, M., Touze, E., Lorber, B., Florentz, C., Giege, R., Sauter, C., Rudinger-Thirion, J.
Deposit date:2007-04-13
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Human Mitochondrial Tyrosyl-tRNA Synthetase Reveals Common and Idiosyncratic Features.
Structure, 15, 2007
3ZXI
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL TYROSYL-TRNA SYNTHETASE IN COMPLEX WITH A TYROSYL-ADENYLATE ANALOG
Descriptor:TYROSYL-TRNA SYNTHETASE, MITOCHONDRIAL, PHOSPHORIC ACID 2-AMINO-3-(4-HYDROXY-PHENYL)-PROPYL ESTER ADENOSIN-5'YL ESTER
Authors:Bonnefond, L., Frugier, M., Rudinger-Thirion, J., Balg, C., Chenevert, R., Lorber, B., Giege, R., Sauter, C.
Deposit date:2011-08-11
Release date:2011-11-16
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Exploiting Protein Engineering and Crystal Polymorphism for Successful X-Ray Structure Determination
Cryst.Growth Des., 11, 2011
4UP7
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CRYSTAL STRUCTURE OF ENTAMOEBA HISTOLYTICA LYSYL-TRNA SYNTHETASE IN COMPLEX WITH LYSYL-ADENYLATE
Descriptor:LYSINE--TRNA LIGASE, ADENOSINE-5'-[LYSYL-PHOSPHATE]
Authors:Bonnefond, L., Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
4UP8
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CRYSTAL STRUCTURE OF ENTAMOEBA HISTOLYTICA LYSYL-TRNA SYNTHETASE APO FORM
Descriptor:LYSINE--TRNA LIGASE
Authors:Bonnefond, L., Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.896 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
4UP9
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CRYSTAL STRUCTURE OF ENTAMOEBA HISTOLYTICA LYSYL-TRNA SYNTHETASE IN COMPLEX WITH ATP
Descriptor:LYSINE--TRNA LIGASE, ADENOSINE-5'-TRIPHOSPHATE
Authors:Bonnefond, L., Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.047 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
4UPA
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CRYSTAL STRUCTURE OF ENTAMOEBA HISTOLYTICA LYSYL-TRNA SYNTHETASE IN COMPLEX WITH AMPPNP
Descriptor:LYSINE--TRNA LIGASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Bonnefond, L., Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
3OQH
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CRYSTAL STRUCTURE OF B. LICHENIFORMIS CDPS YVMC-BLIC
Descriptor:Putative uncharacterized protein yvmC, GLYCEROL
Authors:Bonnefond, L., Arai, T., Suzuki, T., Ishitani, R., Nureki, O.
Deposit date:2010-09-03
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OQI
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CRYSTAL STRUCTURE OF B. LICHENIFORMIS CDPS YVMC-BLIC IN COMPLEX WITH CHES
Descriptor:Putative uncharacterized protein yvmC, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL
Authors:Bonnefond, L., Arai, T., Suzuki, T., Ishitani, R., Nureki, O.
Deposit date:2010-09-03
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OQJ
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CRYSTAL STRUCTURE OF B. LICHENIFORMIS CDPS YVMC-BLIC IN COMPLEX WITH CAPSO
Descriptor:Putative uncharacterized protein yvmC, (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid
Authors:Bonnefond, L., Arai, T., Suzuki, T., Ishitani, R., Nureki, O.
Deposit date:2010-09-03
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog.
Proc.Natl.Acad.Sci.USA, 108, 2011
3S7T
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CRYSTAL STRUCTURE OF SEMET B. LICHENIFORMIS CDPS YVMC-BLIC
Descriptor:Putative uncharacterized protein yvmC
Authors:Bonnefond, L., Ishitani, R., Nureki, O.
Deposit date:2011-05-26
Release date:2011-06-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.808 Å)
Cite:Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog.
Proc.Natl.Acad.Sci.USA, 108, 2011
4C03
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CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 REDUCED
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, SINEFUNGIN
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C04
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CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH INHIBITOR
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, SINEFUNGIN
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C05
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CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH SAH
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C06
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CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH MGCL2
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, MAGNESIUM ION
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C07
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CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH CACL2 AT 1.5 ANGSTROMS
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, CALCIUM ION
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C08
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CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH CACL2 AT 1.34 ANGSTROMS
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, PENTAETHYLENE GLYCOL, CALCIUM ION
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.338 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
5FIW
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CRYSTAL STRUCTURE OF HUMAN MYELOPEROXIDASE AT 1.7 ANGSTROMS RESOLUTION
Descriptor:MYELOPEROXIDASE, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Bonnefond, L., Cavarelli, J.
Deposit date:2015-10-02
Release date:2015-10-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Human Myeloperoxidase at 1.7 Angstroms Resolution
To be Published
5FQN
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CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH SAH AT 1.65 ANGSTROMS
Descriptor:PROTEIN ARGININE METHYLTRANSFERASE 6, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Bonnefond, L., Cavarelli, J.
Deposit date:2015-12-14
Release date:2017-01-18
Method:X-RAY DIFFRACTION (1.657 Å)
Cite:Crystal Strcutures of Prmt6 in Complex with Sah in Alternative Conformations
To be Published
5FQO
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CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH SAH AND MAGNESIUM
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, S-ADENOSYL-L-HOMOCYSTEINE, MAGNESIUM ION
Authors:Bonnefond, L., Cavarelli, J.
Deposit date:2015-12-14
Release date:2017-01-18
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Crystal Strcutures of Prmt6 in Complex with Sah in Alternative Conformations
To be Published
5LV2
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR LH1246
Descriptor:Histone-arginine methyltransferase CARM1, 5'-S-[(3S)-3-azaniumyl-3-carboxypropyl]-5'-thioadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Troffer-Charlier, N., Halby, L., Arimondo, P., Bonnefond, L., Cavarelli, J.
Deposit date:2016-09-12
Release date:2017-09-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors.
Philos.Trans.R.Soc.Lond.B Biol.Sci., 373, 2018
5LV3
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH LIGAND LH1561BR
Descriptor:Histone-arginine methyltransferase CARM1, S-ADENOSYL-L-HOMOCYSTEINE, 5-[[2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethylamino]methyl]-4-azanyl-1-[2-(4-bromanylphenoxy)ethyl]pyrimidin-2-one
Authors:Cura, V., Marechal, N., Troffer-Charlier, N., Halby, L., Arimondo, P., Bonnefond, L., Cavarelli, J.
Deposit date:2016-09-12
Release date:2017-09-20
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors.
Philos. Trans. R. Soc. Lond., B, Biol. Sci., 373, 2018
5LV4
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CRYSTAL STRUCTURE OF MOUSE PRMT6 IN COMPLEX WITH INHIBITOR LH1236
Descriptor:Protein arginine N-methyltransferase 6, (2~{R})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]amino]-2-azanyl-butanoic acid
Authors:Cura, V., Marechal, N., Troffer-Charlier, N., Halby, L., Arimondo, P., Bonnefond, L., Cavarelli, J.
Deposit date:2016-09-12
Release date:2017-09-20
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors.
Philos. Trans. R. Soc. Lond., B, Biol. Sci., 373, 2018
5LV5
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CRYSTAL STRUCTURE OF MOUSE PRMT6 IN COMPLEX WITH INHIBITOR LH1458
Descriptor:Protein arginine N-methyltransferase 6, 2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]-[(3~{S})-3-azanyl-4-oxidanyl-4-oxidanylidene-butyl]azanium
Authors:Cura, V., Marechal, N., Troffer-Charlier, N., Halby, L., Arimondo, P., Bonnefond, L., Cavarelli, J.
Deposit date:2016-09-12
Release date:2017-09-20
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors.
Philos. Trans. R. Soc. Lond., B, Biol. Sci., 373, 2018
5TBH
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR LH1236
Descriptor:Histone-arginine methyltransferase CARM1, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Troffer-Charlier, N., Halby, L., Arimondo, P., Bonnefond, L., Cavarelli, J.
Deposit date:2016-09-12
Release date:2017-09-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.341 Å)
Cite:Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors.
Philos.Trans.R.Soc.Lond.B Biol.Sci., 373, 2018
5TBI
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR LH1427
Descriptor:Histone-arginine methyltransferase CARM1, 1,2-ETHANEDIOL, 5'-S-[(3S)-3-azaniumyl-3-carboxypropyl]-5'-thioadenosine, ...
Authors:Cura, V., Marechal, N., Troffer-Charlier, N., Halby, L., Arimondo, P., Bonnefond, L., Cavarelli, J.
Deposit date:2016-09-12
Release date:2017-09-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors.
Philos.Trans.R.Soc.Lond.B Biol.Sci., 373, 2018
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