Author results

2WP8
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YEAST RRP44 NUCLEASE
Descriptor:EXOSOME COMPLEX COMPONENT RRP45, EXOSOME COMPLEX COMPONENT SKI6, EXOSOME COMPLEX EXONUCLEASE DIS3, ...
Authors:Basquin, J., Bonneau, F., Ebert, J., Lorentzen, E., Conti, E.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Yeast Exosome Functions as a Macromolecular Cage to Channel RNA Substrates for Degradation.
Cell(Cambridge,Mass.), 139, 2009
2D4Q
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CRYSTAL STRUCTURE OF THE SEC-PH DOMAIN OF THE HUMAN NEUROFIBROMATOSIS TYPE 1 PROTEIN
Descriptor:Neurofibromin, OXTOXYNOL-10, PYROPHOSPHATE 2-
Authors:D'angelo, I., Welti, S., Bonneau, F., Scheffzek, K.
Deposit date:2005-10-22
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A novel bipartite phospholipid-binding module in the neurofibromatosis type 1 protein
Embo Rep., 7, 2006
2XZL
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UPF1-RNA COMPLEX
Descriptor:ATP-DEPENDENT HELICASE NAM7, 5- R(*UP*UP*UP*UP*UP*UP*UP*UP*U) -3, ZINC ION, ...
Authors:Chakrabarti, S., Jayachandran, U., Bonneau, F., Fiorini, F., Basquin, C., Domcke, S., Le Hir, H., Conti, E.
Deposit date:2010-11-26
Release date:2011-03-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
2XZO
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UPF1 HELICASE - RNA COMPLEX
Descriptor:REGULATOR OF NONSENSE TRANSCRIPTS 1, 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', PENTAETHYLENE GLYCOL, ...
Authors:Chakrabarti, S., Jayachandran, U., Bonneau, F., Fiorini, F., Basquin, C., Domcke, S., Le Hir, H., Conti, E.
Deposit date:2010-11-26
Release date:2011-03-30
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.395 Å)
Cite:Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
2XZP
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UPF1 HELICASE
Descriptor:REGULATOR OF NONSENSE TRANSCRIPTS 1, GLYCEROL, MALONATE ION
Authors:Chakrabarti, S., Jayachandran, U., Bonneau, F., Fiorini, F., Basquin, C., Domcke, S., Le Hir, H., Conti, E.
Deposit date:2010-11-26
Release date:2011-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
6EJ5
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A CONSERVED STRUCTURAL ELEMENT IN THE RNA HELICASE UPF1 REGULATES ITS CATALYTIC ACTIVITY IN AN ISOFORM-SPECIFIC MANNER
Descriptor:Regulator of nonsense transcripts 1
Authors:Gowravaram, M., Bonneau, F., Maciej, V.D., Chakrabarti, S.
Deposit date:2017-09-20
Release date:2018-01-24
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner.
Nucleic Acids Res., 46, 2018
2XGJ
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STRUCTURE OF MTR4, A DEXH HELICASE INVOLVED IN NUCLEAR RNA PROCESSING AND SURVEILLANCE
Descriptor:ATP-DEPENDENT RNA HELICASE DOB1, RNA (5'-(*AP*AP*AP*AP*A)-3'), ADENOSINE-5'-DIPHOSPHATE
Authors:Weir, J.R., Bonneau, F., Hentschel, J., Conti, E.
Deposit date:2010-06-04
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Analysis Reveals the Characteristic Features of Mtr4, a Dexh Helicase Involved in Nuclear RNA Processing and Surveillance.
Proc.Natl.Acad.Sci.USA, 107, 2010
3BXJ
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CRYSTAL STRUCTURE OF THE C2-GAP FRAGMENT OF SYNGAP
Descriptor:Ras GTPase-activating protein SynGAP
Authors:Pena, V., Hothorn, M., Eberth, A., Kaschau, N., Parret, A., Gremer, L., Bonneau, F., Ahmadian, M.R., Scheffzek, K.
Deposit date:2008-01-14
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction.
Embo Rep., 9, 2008
3N89
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KH DOMAINS
Descriptor:Defective in germ line development protein 3, isoform a
Authors:Nakel, K., Hartung, S.A., Bonneau, F., Eckmann, C.R., Conti, E.
Deposit date:2010-05-28
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform.
Rna, 16, 2010
4U4C
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THE MOLECULAR ARCHITECTURE OF THE TRAMP COMPLEX REVEALS THE ORGANIZATION AND INTERPLAY OF ITS TWO CATALYTIC ACTIVITIES
Descriptor:ATP-dependent RNA helicase DOB1, Protein AIR2,Poly(A) RNA polymerase protein 2, SULFATE ION, ...
Authors:Falk, S., Weir, J.R., Hentschel, J., Reichelt, P., Bonneau, F., Conti, E.
Deposit date:2014-07-23
Release date:2014-09-24
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities.
Mol.Cell, 55, 2014
4UM2
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CRYSTAL STRUCTURE OF THE TPR DOMAIN OF SMG6
Descriptor:TELOMERASE-BINDING PROTEIN EST1A, GLYCEROL
Authors:Chakrabarti, S., Bonneau, F., Schuessler, S., Eppinger, E., Conti, E.
Deposit date:2014-05-14
Release date:2014-07-23
Last modified:2014-08-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Phospho-Dependent and Phospho-Independent Interactions of the Helicase Upf1 with the Nmd Factors Smg5-Smg7 and Smg6.
Nucleic Acids Res., 42, 2014
4XR7
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STRUCTURE OF THE SACCHAROMYCES CEREVISIAE PAN2-PAN3 CORE COMPLEX
Descriptor:PAB-dependent poly(A)-specific ribonuclease subunit PAN2, PAB-dependent poly(A)-specific ribonuclease subunit PAN3
Authors:Schafer, I.B., Rode, M., Bonneau, F., Schussler, S., Conti, E.
Deposit date:2015-01-20
Release date:2015-01-28
Method:X-RAY DIFFRACTION (3.796 Å)
Cite:The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Nat. Struct. Mol. Biol., 21, 2014
4ZRL
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STRUCTURE OF THE NON CANONICAL POLY(A) POLYMERASE COMPLEX GLD-2 - GLD-3
Descriptor:Poly(A) RNA polymerase gld-2, Defective in germ line development protein 3, CHLORIDE ION
Authors:Nakel, K., Bonneau, F., Eckmann, C.R., Conti, E.
Deposit date:2015-05-12
Release date:2015-07-08
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural basis for the activation of the C. elegans noncanonical cytoplasmic poly(A)-polymerase GLD-2 by GLD-3.
Proc.Natl.Acad.Sci.USA, 112, 2015
5JNB
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STRUCTURE OF GLD-2/RNP-8 COMPLEX
Descriptor:Poly(A) RNA polymerase gld-2, RNP (RRM RNA binding domain) containing, SULFATE ION, ...
Authors:Nakel, K., Bonneau, F., Basquin, C., Eckmann, C.R., Conti, E.
Deposit date:2016-04-29
Release date:2016-06-22
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.486 Å)
Cite:Structural basis for the antagonistic roles of RNP-8 and GLD-3 in GLD-2 poly(A)-polymerase activity.
Rna, 22, 2016
4CT4
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CNOT1 MIF4G DOMAIN - DDX6 COMPLEX
Descriptor:CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6, MAGNESIUM ION, ...
Authors:Ozgur, S., Basquin, J., Conti, E.
Deposit date:2014-03-12
Release date:2014-05-07
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Biochemical Insights to the Role of the Ccr4- not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
4CT5
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DDX6
Descriptor:DDX6, ACETATE ION
Authors:Ozgur, S., Basquin, J., Conti, E.
Deposit date:2014-03-12
Release date:2014-05-07
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
4CT6
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CNOT9-CNOT1 COMPLEX
Descriptor:CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG
Authors:Basquin, J., Ozgur, S., Conti, E.
Deposit date:2014-03-12
Release date:2014-05-07
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
4CT7
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CNOT9-CNOT1 COMPLEX WITH BOUND TRYPTOPHAN
Descriptor:CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, TRYPTOPHAN, ...
Authors:Basquin, J., Ozgur, S., Conti, E.
Deposit date:2014-03-12
Release date:2014-05-07
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
4CV5
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YEAST NOT1 CN9BD-CAF40 COMPLEX
Descriptor:GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, PROTEIN CAF40, HEXATANTALUM DODECABROMIDE
Authors:Basquin, J., Conti, E.
Deposit date:2014-03-23
Release date:2014-05-07
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (3.807 Å)
Cite:Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
4Q8G
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STRUCTURE OF THE SACCHAROMYCES CEREVISIAE PAN2 PSEUDOUBIQUITIN-HYDROLASE
Descriptor:PAB-dependent poly(A)-specific ribonuclease subunit PAN2, ZINC ION
Authors:Schaefer, I.B., Conti, E.
Deposit date:2014-04-27
Release date:2014-06-04
Last modified:2014-07-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Nat.Struct.Mol.Biol., 21, 2014
4Q8H
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STRUCTURE OF THE SACCHAROMYCES CEREVISIAE PAN2 PSEUDOUBIQUITIN-HYDROLASE-RNASE MODULE
Descriptor:PAB-dependent poly(A)-specific ribonuclease subunit PAN2, MAGNESIUM ION
Authors:Schaefer, I.B., Conti, E.
Deposit date:2014-04-27
Release date:2014-06-04
Last modified:2014-07-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Nat.Struct.Mol.Biol., 21, 2014
4W8V
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CRYSTAL STRUCTURE OF CMR6 FROM PYROCOCCUS FURIOSUS
Descriptor:CRISPR system Cmr subunit Cmr6
Authors:Benda, C., Ebert, J., Baumgaertner, M., Conti, E.
Deposit date:2014-08-26
Release date:2014-10-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4.
Mol.Cell, 56, 2014
4W8W
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CRYSTAL STRUCTURE OF OLIGOMERIC CMR4 FROM PYROCOCCUS FURIOSUS
Descriptor:CRISPR system Cmr subunit Cmr4
Authors:Benda, C., Ebert, J., Baumgaertner, M., Conti, E.
Deposit date:2014-08-26
Release date:2014-10-15
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4.
Mol.Cell, 56, 2014
4W8X
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CRYSTAL STRUCTURE OF CMR1 FROM PYROCOCCUS FURIOSUS BOUND TO A NUCLEOTIDE
Descriptor:CRISPR system Cmr subunit Cmr1-1, PHOSPHATE ION, GUANOSINE-3'-MONOPHOSPHATE
Authors:Benda, C., Ebert, J., Baumgaertner, M., Conti, E.
Deposit date:2014-08-26
Release date:2014-10-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4.
Mol.Cell, 56, 2014
4W8Y
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STRUCTURE OF FULL LENGTH CMR2 FROM PYROCOCCUS FURIOSUS (MANGANESE BOUND FORM)
Descriptor:CRISPR system Cmr subunit Cmr2, ZINC ION, MANGANESE (II) ION
Authors:Benda, C., Ebert, J., Baumgaertner, M., Conti, E.
Deposit date:2014-08-26
Release date:2014-10-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4.
Mol.Cell, 56, 2014
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