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2LPR
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STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1991-08-05
公開日1993-01-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
3LPR
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STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1991-08-05
公開日1993-01-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
6LPR
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STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1991-08-05
公開日1993-01-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
9LPR
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STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1991-08-05
公開日1993-01-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
1P01
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SERINE PROTEASE MECHANISM. STRUCTURE OF AN INHIBITORY COMPLEX OF ALPHA-LYTIC PROTEASE AND A TIGHTLY BOUND PEPTIDE BORONIC ACID
分子名称:ALPHA-LYTIC PROTEASE, N-(tert-butoxycarbonyl)-L-alanyl-N-[(1R)-1-(dihydroxyboranyl)-2-methylpropyl]-L-prolinamide, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Serine protease mechanism: structure of an inhibitory complex of alpha-lytic protease and a tightly bound peptide boronic acid.
Biochemistry, 26, 1987
1P02
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STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates.
Biochemistry, 28, 1989
1P03
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STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates.
Biochemistry, 28, 1989
1P04
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STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ISOLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates.
Biochemistry, 28, 1989
1P05
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STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates.
Biochemistry, 28, 1989
1P06
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STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates.
Biochemistry, 28, 1989
1P09
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STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES
分子名称:ALPHA-LYTIC PROTEASE, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural plasticity broadens the specificity of an engineered protease.
Nature, 339, 1989
1P10
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STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural plasticity broadens the specificity of an engineered protease.
Nature, 339, 1989
1IMA
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STRUCTURAL ANALYSIS OF INOSITOL MONOPHOSPHATASE COMPLEXES WITH SUBSTRATES
分子名称:INOSITOL MONOPHOSPHATASE, GADOLINIUM ATOM, D-MYO-INOSITOL-1-PHOSPHATE
著者Bone, R.
登録日1994-02-08
公開日1995-02-27
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of inositol monophosphatase complexes with substrates.
Biochemistry, 33, 1994
1IMB
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STRUCTURAL ANALYSIS OF INOSITOL MONOPHOSPHATASE COMPLEXES WITH SUBSTRATES
分子名称:INOSITOL MONOPHOSPHATASE, GADOLINIUM ATOM, L-MYO-INOSITOL-1-PHOSPHATE
著者Bone, R.
登録日1994-02-08
公開日1995-02-27
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of inositol monophosphatase complexes with substrates.
Biochemistry, 33, 1994
1IMC
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STRUCTURAL STUDIES OF METAL BINDING BY INOSITOL MONOPHOSPHATASE: EVIDENCE FOR TWO-METAL ION CATALYSIS
分子名称:INOSITOL MONOPHOSPHATASE, MANGANESE (II) ION, CHLORIDE ION
著者Bone, R.
登録日1994-02-08
公開日1995-02-27
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis.
Biochemistry, 33, 1994
1IMD
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STRUCTURAL STUDIES OF METAL BINDING BY INOSITOL MONOPHOSPHATASE: EVIDENCE FOR TWO-METAL ION CATALYSIS
分子名称:INOSITOL MONOPHOSPHATASE, MANGANESE (II) ION, PHOSPHATE ION
著者Bone, R.
登録日1994-02-08
公開日1995-02-27
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis.
Biochemistry, 33, 1994
1IME
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STRUCTURAL STUDIES OF METAL BINDING BY INOSITOL MONOPHOSPHATASE: EVIDENCE FOR TWO-METAL ION CATALYSIS
分子名称:INOSITOL MONOPHOSPHATASE, CALCIUM ION
著者Bone, R.
登録日1994-02-08
公開日1995-02-27
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis.
Biochemistry, 33, 1994
1IMF
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STRUCTURAL STUDIES OF METAL BINDING BY INOSITOL MONOPHOSPHATASE: EVIDENCE FOR TWO-METAL ION CATALYSIS
分子名称:INOSITOL MONOPHOSPHATASE
著者Bone, R.
登録日1994-02-08
公開日1995-02-27
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis.
Biochemistry, 33, 1994
4PHV
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X-RAY CRYSTAL STRUCTURE OF THE HIV PROTEASE COMPLEX WITH L-700,417, AN INHIBITOR WITH PSEUDO C2 SYMMETRY
分子名称:HIV-1 PROTEASE, N,N-BIS(2-HYDROXY-1-INDANYL)-2,6- DIPHENYLMETHYL-4-HYDROXY-1,7-HEPTANDIAMIDE
著者Bone, R.
登録日1991-10-04
公開日1993-10-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-Ray Crystal Structure of the HIV Protease Complex with L-700,417, an Inhibitor with Pseudo C2 Symmetry
J.Am.Chem.Soc., 113, 1991
2HHM
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STRUCTURE OF INOSITOL MONOPHOSPHATASE, THE PUTATIVE TARGET OF LITHIUM THERAPY
分子名称:INOSITOL MONOPHOSPHATASE, SULFATE ION, GADOLINIUM ATOM
著者Bone, R.
登録日1992-10-20
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of inositol monophosphatase, the putative target of lithium therapy.
Proc.Natl.Acad.Sci.USA, 89, 1992
1P11
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CRYSTAL STRUCTURES OF ALPHA-LYTIC PROTEASE COMPLEXES WITH IRREVERSIBLY BOUND PHOSPHONATE ESTERS
分子名称:ALPHA-LYTIC PROTEASE, PHOSPHONATE ESTER INHIBITOR A, PHOSPHONATE ESTER INHIBITOR B(TRANSITION STATE), ...
著者Bone, R., Agard, D.A.
登録日1990-10-26
公開日1993-01-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters.
Biochemistry, 30, 1991
1P12
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CRYSTAL STRUCTURES OF ALPHA-LYTIC PROTEASE COMPLEXES WITH IRREVERSIBLY BOUND PHOSPHONATE ESTERS
分子名称:ALPHA-LYTIC PROTEASE, PHOSPHONATE ESTER INHIBITOR, SULFATE ION
著者Bone, R., Agard, D.A.
登録日1990-10-26
公開日1993-01-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters.
Biochemistry, 30, 1991
1QBV
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CRYSTAL STRUCTURE OF THROMBIN COMPLEXED WITH AN GUANIDINE-MIMETIC INHIBITOR
分子名称:THROMBIN (LIGHT CHAIN), THROMBIN (HEAVY CHAIN), Hirudin, ...
著者Bone, R., Lu, T., Illig, C.R., Soll, R.M., Spurlino, J.C.
登録日1999-04-27
公開日1999-10-27
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of thrombin complexed with potent inhibitors incorporating a phenyl group as a peptide mimetic and aminopyridines as guanidine substitutes.
J.Med.Chem., 41, 1998
5LPR
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STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Fujishige, A., Bone, R., Agard, D.A.
登録日1991-08-05
公開日1993-01-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
7LPR
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STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者Fujishige, A., Bone, R., Agard, D.A.
登録日1991-08-05
公開日1993-01-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
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