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1C8Z
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C-TERMINAL DOMAIN OF MOUSE BRAIN TUBBY PROTEIN
Descriptor:TUBBY PROTEIN, PHOSPHATE ION
Authors:Boggon, T.J., Myers, S.C., Shapiro, L.
Deposit date:1999-07-30
Release date:1999-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Implication of tubby proteins as transcription factors by structure-based functional analysis.
Science, 286, 1999
1L3W
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C-CADHERIN ECTODOMAIN
Descriptor:EP-cadherin, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Boggon, T.J., Murray, J., Chappuis-Flament, S., Wong, E., Gumbiner, B.M., Shapiro, L.
Deposit date:2002-03-01
Release date:2002-04-26
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:C-cadherin ectodomain structure and implications for cell adhesion mechanisms
Science, 296, 2002
1YVJ
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CRYSTAL STRUCTURE OF THE JAK3 KINASE DOMAIN IN COMPLEX WITH A STAUROSPORINE ANALOGUE
Descriptor:Tyrosine-protein kinase JAK3, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE
Authors:Boggon, T.J., Li, Y., Manley, P.W., Eck, M.J.
Deposit date:2005-02-15
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog
Blood, 106, 2005
233D
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THE CRYSTAL STRUCTURE ANALYSIS OF D(CGCGAASSCGCG)2: A SYNTHETIC DNA DODECAMER DUPLEX CONTAINING FOUR 4'-THIO-2'-DEOXYTHYMIDINE NUCLEOTIDES
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*)-D(*(T49)P*(T49)P*)-D(*CP*GP*CP*G)-3')
Authors:Boggon, T.J., Hancox, E.L., McAuley-Hecht, K.E., Connolly, B.A., Hunter, W.N., Brown, T., Walker, R.T., Leonard, G.A.
Deposit date:1995-10-16
Release date:1996-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides.
Nucleic Acids Res., 24, 1996
1I7E
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C-TERMINAL DOMAIN OF MOUSE BRAIN TUBBY PROTEIN BOUND TO PHOSPHATIDYLINOSITOL 4,5-BIS-PHOSPHATE
Descriptor:TUBBY PROTEIN, L-ALPHA-GLYCEROPHOSPHO-D-MYO-INOSITOL-4,5-BIS-PHOSPHATE
Authors:Santagata, S., Boggon, T.J., Baird, C.L., Shan, W.S., Shapiro, L.
Deposit date:2001-03-08
Release date:2001-06-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:G-protein signaling through tubby proteins.
Science, 292, 2001
1BVX
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THE 1.8 A STRUCTURE OF GEL GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
Descriptor:PROTEIN (LYSOZYME)
Authors:Dong, J., Boggon, T.J., Chayen, N.E., Raftery, J., Bi, R.C., Helliwell, J.R.
Deposit date:1998-09-18
Release date:1998-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1BWH
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THE 1.8 A STRUCTURE OF GROUND CONTROL GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
Descriptor:PROTEIN (LYSOZYME)
Authors:Dong, J., Boggon, T.J., Chayen, N.E., Raftery, J., Bi, R.C.
Deposit date:1998-09-24
Release date:1998-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1BWI
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THE 1.8 A STRUCTURE OF MICROBATCH OIL DROP GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
Descriptor:PROTEIN (LYSOZYME)
Authors:Dong, J., Boggon, T.J., Chayen, N.E., Raftery, J., Bi, R.C.
Deposit date:1998-09-24
Release date:1998-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1BWJ
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THE 1.8 A STRUCTURE OF MICROGRAVITY GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
Descriptor:PROTEIN (LYSOZYME)
Authors:Dong, J., Boggon, T.J., Chayen, N.E., Raftery, J., Bi, R.C.
Deposit date:1998-09-18
Release date:1998-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1OBQ
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APOCRUSTACYANIN C1 CRYSTALS GROWN IN SPACE AND EARTH USING VAPOUR DIFFUSION GEOMETRY
Descriptor:CRUSTACYANIN C1 SUBUNIT
Authors:Habash, J., Boggon, T.J., Raftery, J., Chayen, N.E., Zagalsky, P.F., Helliwell, J.R.
Deposit date:2003-01-31
Release date:2003-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Apocrustacyanin C(1) Crystals Grown in Space and on Earth Using Vapour-Diffusion Geometry: Protein Structure Refinements and Electron-Density Map Comparisons
Acta Crystallogr.,Sect.D, 59, 2003
1OBU
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APOCRUSTACYANIN C1 CRYSTALS GROWN IN SPACE AND EARTH USING VAPOUR DIFFUSION GEOMETRY
Descriptor:CRUSTACYANIN C1 SUBUNIT
Authors:Habash, J., Boggon, T.J., Raftery, J., Chayen, N.E., Zagalsky, P.F., Helliwell, J.R.
Deposit date:2003-01-31
Release date:2003-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Apocrustacyanin C(1) Crystals Grown in Space and on Earth Using Vapour-Diffusion Geometry: Protein Structure Refinements and Electron-Density Map Comparisons
Acta Crystallogr.,Sect.D, 59, 2003
2ITN
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AMP-PNP
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2ITO
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH IRESSA
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, Gefitinib
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2014-10-15
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2ITP
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AEE788
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR PRECURSOR, 6-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]PHENYL}-N-[(1R)-1-PHENYLETHYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2ITQ
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AFN941
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, 1,2,3,4-Tetrahydrogen Staurosporine
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2ITT
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN L858R MUTATION IN COMPLEX WITH AEE788
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, 6-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]PHENYL}-N-[(1R)-1-PHENYLETHYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2ITU
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN L858R MUTATION IN COMPLEX WITH AFN941
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, 1,2,3,4-Tetrahydrogen Staurosporine
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2ITV
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN L858R MUTATION IN COMPLEX WITH AMP-PNP
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2ITW
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN IN COMPLEX WITH AFN941
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, 1,2,3,4-Tetrahydrogen Staurosporine
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2ITX
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN IN COMPLEX WITH AMP-PNP
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2ITY
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN IN COMPLEX WITH IRESSA
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, Gefitinib
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2014-10-15
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2ITZ
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN L858R MUTATION IN COMPLEX WITH IRESSA
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, CHLORIDE ION, Gefitinib
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-05-25
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2J6M
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN IN COMPLEX WITH AEE788
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, 6-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]PHENYL}-N-[(1R)-1-PHENYLETHYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
Authors:Yun, C.-H., Boggon, T.J., Li, Y., Woo, S., Greulich, H., Meyerson, M., Eck, M.J.
Deposit date:2006-09-29
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007
2KQ6
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THE STRUCTURE OF THE EF-HAND DOMAIN OF POLYCYSTIN-2 SUGGESTS A MECHANISM FOR CA2+-DEPENDENT REGULATION OF POLYCYSTIN-2 CHANNEL ACTIVITY
Descriptor:Polycystin-2
Authors:Petri, E.T., Celic, A., Kennedy, S.D., Ehrlich, B.E., Boggon, T.J., Hodsdon, M.E.
Deposit date:2009-10-28
Release date:2010-05-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity.
Proc.Natl.Acad.Sci.USA, 107, 2010
3F6Q
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CRYSTAL STRUCTURE OF INTEGRIN-LINKED KINASE ANKYRIN REPEAT DOMAIN IN COMPLEX WITH PINCH1 LIM1 DOMAIN
Descriptor:Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, IODIDE ION, ...
Authors:Chiswell, B.P., Calderwood, D.A., Boggon, T.J.
Deposit date:2008-11-06
Release date:2008-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structural basis of integrin-linked kinase-PINCH interactions.
Proc.Natl.Acad.Sci.USA, 105, 2008