Author results

1FGU
  • Download 1fgu
  • View 1fgu
Molmil generated image of 1fgu
SSDNA-BINDING DOMAIN OF THE LARGE SUBUNIT OF REPLICATION PROTEIN A
Descriptor:REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT
Authors:Bochkareva, E., Belegu, V., Korolev, S., Bochkarev, A.
Deposit date:2000-07-28
Release date:2001-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the major single-stranded DNA-binding domain of replication protein A suggests a dynamic mechanism for DNA binding.
EMBO J., 20, 2001
2B29
  • Download 2b29
  • View 2b29
Molmil generated image of 2b29
N-TERMINAL DOMAIN OF THE RPA70 SUBUNIT OF HUMAN REPLICATION PROTEIN A.
Descriptor:Replication protein A 70 kDa DNA-binding subunit
Authors:Bochkareva, E., Kaustov, L., Ayed, A., Okorokov, A., Milner, J., Arrowsmith, C.H., Bochkarev, A.
Deposit date:2005-09-18
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2B3G
  • Download 2b3g
  • View 2b3g
Molmil generated image of 2b3g
P53N (FRAGMENT 33-60) BOUND TO RPA70N
Descriptor:Replication protein A 70 kDa DNA-binding subunit, Cellular tumor antigen p53
Authors:Bochkareva, E., Kaustov, L., Ayed, A., Yi, G.S., Lu, Y., Pineda-Lucena, A., Liao, J.C., Okorokov, A.L., Milner, J., Arrowsmith, C.H., Bochkarev, A.
Deposit date:2005-09-20
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2ITL
  • Download 2itl
  • View 2itl
Molmil generated image of 2itl
THE ORIGIN BINDING DOMAIN OF THE SV40 LARGE T ANTIGEN BOUND TO THE FUNCTIONAL PEN PALINDROME DNA (23 BP)
Descriptor:24-nt PEN element of the SV40 DNA origin, large T antigen
Authors:Bochkareva, E., Seitova, A., Bochkarev, A.
Deposit date:2006-10-19
Release date:2006-12-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
Embo J., 25, 2006
2IPR
  • Download 2ipr
  • View 2ipr
Molmil generated image of 2ipr
ORIGIN BINDING DOMAIN OF THE SV40 LARGE T ANTIGEN (RESIDUES 131-259). P21 CRYSTAL FORM
Descriptor:large T antigen
Authors:Martynowski, D., Bochkareva, E., Bochkarev, A.
Deposit date:2006-10-12
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
Embo J., 25, 2006
2ITJ
  • Download 2itj
  • View 2itj
Molmil generated image of 2itj
ORIGIN BINDING DOMAIN OF THE SV40 LARGE T ANTIGEN (RESIDUES 131-259). P212121 CRYSTAL FORM
Descriptor:large T antigen
Authors:Martynowski, D., Bochkareva, E., Bochkarev, A.
Deposit date:2006-10-19
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
Embo J., 25, 2006
2NL8
  • Download 2nl8
  • View 2nl8
Molmil generated image of 2nl8
THE ORIGIN BINDING DOMAIN OF THE SV40 LARGE T ANTIGEN BOUND NON SPECIFICALLY TO A 17 BP PALINDROME DNA (SITES 1 AND 3)
Descriptor:18-nt PEN element of the SV40 DNA origin, large T antigen
Authors:Martynowski, D., Bochkareva, E., Bochkarev, A.
Deposit date:2006-10-19
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
Embo J., 25, 2006
1B3T
  • Download 1b3t
  • View 1b3t
Molmil generated image of 1b3t
EBNA-1 NUCLEAR PROTEIN/DNA COMPLEX
Descriptor:DNA (5'-D(*GP*GP*GP*AP*AP*GP*CP*AP*TP*AP*TP*GP*CP*TP*TP*CP*CP*C)-3'), PROTEIN (NUCLEAR PROTEIN EBNA1)
Authors:Bochkarev, A., Bochkareva, E., Edwards, A., Frappier, L.
Deposit date:1998-12-14
Release date:1998-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The 2.2 A structure of a permanganate-sensitive DNA site bound by the Epstein-Barr virus origin binding protein, EBNA1.
J.Mol.Biol., 284, 1998
1QUQ
  • Download 1quq
  • View 1quq
Molmil generated image of 1quq
COMPLEX OF REPLICATION PROTEIN A SUBUNITS RPA14 AND RPA32
Descriptor:PROTEIN (REPLICATION PROTEIN A 32 KD SUBUNIT), PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT)
Authors:Bochkarev, A., Bochkareva, E., Frappier, L., Edwards, A.M.
Deposit date:1999-07-02
Release date:1999-08-13
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding.
EMBO J., 18, 1999
2AEP
  • Download 2aep
  • View 2aep
Molmil generated image of 2aep
AN EPIDEMIOLOGICALLY SIGNIFICANT EPITOPE OF A 1998 INFLUENZA VIRUS NEURAMINIDASE FORMS A HIGHLY HYDRATED INTERFACE IN THE NA-ANTIBODY COMPLEX.
Descriptor:neuraminidase, FAB heavy chain, FAB light chain, ...
Authors:Venkatramani, L., Bochkareva, E., Lee, J.T., Gulati, U., Laver, W.G., Bochkarev, A., Air, G.M.
Deposit date:2005-07-23
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An Epidemiologically Significant Epitope of a 1998 Human Influenza Virus Neuraminidase Forms a Highly Hydrated Interface in the NA-Antibody Complex
J.Mol.Biol., 356, 2006
2ESH
  • Download 2esh
  • View 2esh
Molmil generated image of 2esh
CRYSTAL STRUCTURE OF CONSERVED PROTEIN OF UNKNOWN FUNCTION TM0937- A POTENTIAL TRANSCRIPTIONAL FACTOR
Descriptor:conserved hypothetical protein TM0937, CALCIUM ION
Authors:Liu, Y., Bochkareva, E., Zheng, H., Xu, X., Nocek, B., Lunin, V., Edward, A., Pai, E.F., Joachimiak, A., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-10-26
Release date:2005-12-06
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Conserved Hypothetical Protein TM0937
To be Published
1L1O
  • Download 1l1o
  • View 1l1o
Molmil generated image of 1l1o
STRUCTURE OF THE HUMAN REPLICATION PROTEIN A (RPA) TRIMERIZATION CORE
Descriptor:Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit, Replication protein A 70 kDa DNA-binding subunit, ...
Authors:Bochkareva, E.V., Korolev, S., Lees-Miller, S.P., Bochkarev, A.
Deposit date:2002-02-19
Release date:2002-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA.
EMBO J., 21, 2002
1DPU
  • Download 1dpu
  • View 1dpu
Molmil generated image of 1dpu
SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN RPA32 COMPLEXED WITH UNG2(73-88)
Descriptor:REPLICATION PROTEIN A (RPA32) C-TERMINAL DOMAIN, URACIL DNA GLYCOSYLASE (UNG2)
Authors:Mer, G., Edwards, A.M., Chazin, W.J.
Deposit date:1999-12-27
Release date:2000-11-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA.
Cell(Cambridge,Mass.), 103, 2000
2AEQ
  • Download 2aeq
  • View 2aeq
Molmil generated image of 2aeq
AN EPIDEMIOLOGICALLY SIGNIFICANT EPITOPE OF A 1998 INFLUENZA VIRUS NEURAMINIDASE FORMS A HIGHLY HYDRATED INTERFACE IN THE NA-ANTIBODY COMPLEX.
Descriptor:neuraminidase, FAB light chain, FAB heavy chain, ...
Authors:Venkatramani, L., Bochkarev, A., Air, G.M.
Deposit date:2005-07-23
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:An Epidemiologically Significant Epitope of a 1998 Human Influenza Virus Neuraminidase Forms a Highly Hydrated Interface in the NA-Antibody Complex
J.Mol.Biol., 356, 2006
2IF9
  • Download 2if9
  • View 2if9
Molmil generated image of 2if9
CRYSTAL STRUCTURE OF SV40 T-ANTIGEN ORIGIN BINDING DOMAIN DISULFIDE-LINKED DIMER
Descriptor:Large T antigen
Authors:Meinke, G., Bullock, P.A., Bohm, A.
Deposit date:2006-09-20
Release date:2007-02-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.586 Å)
Cite:The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA
Plos Biol., 5, 2007
2NTC
  • Download 2ntc
  • View 2ntc
Molmil generated image of 2ntc
CRYSTAL STRUCTURE OF SV40 LARGE T ANTIGEN ORIGIN BINDING DOMAIN WITH DNA
Descriptor:21-nt PEN element of the SV40 DNA origin, large T antigen
Authors:Bohm, A., Meinke, G., Bullock, P.A.
Deposit date:2006-11-07
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA
Plos Biol., 5, 2007
1Z1D
  • Download 1z1d
  • View 1z1d
Molmil generated image of 1z1d
STRUCTURAL MODEL FOR THE INTERACTION BETWEEN RPA32 C-TERMINAL DOMAIN AND SV40 T ANTIGEN ORIGIN BINDING DOMAIN.
Descriptor:Replication protein A 32 kDa subunit, Large T antigen
Authors:Arunkumar, A.I., Klimovich, V., Jiang, X., Ott, R.D., Mizoue, L., Fanning, E., Chazin, W.J.
Deposit date:2005-03-03
Release date:2005-05-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome.
Nat.Struct.Mol.Biol., 12, 2005