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4CIS
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STRUCTURE OF MUTM IN COMPLEX WITH CARBOCYCLIC 8-OXO-G CONTAINING DNA
Descriptor:FORMAMIDOPYRIMIDIN DNA GLYCOSYLASE, DNA, ZINC ION, ...
Authors:Schneider, S., Sadeghian, K., Flaig, D., Blank, I.D., Strasser, R., Stathis, D., Winnacker, M., Carell, T., Ochsenfeld, C.
Deposit date:2013-12-15
Release date:2014-06-04
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Ribose-protonated DNA base excision repair: a combined theoretical and experimental study.
Angew. Chem. Int. Ed. Engl., 53, 2014
5ABM
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SHEEP ALDEHYDE DEHYDROGENASE 1A1
Descriptor:RETINAL DEHYDROGENASE 1, [[(2R,3S,4R,5R)-5-[(3R)-3-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanidyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphate, MAGNESIUM ION
Authors:Koch, M.F., Harteis, S., Blank, I.D., Pestel, G., Tietze, L.F., Ochsenfeld, C., Schneider, S., Sieber, S.A.
Deposit date:2015-08-07
Release date:2015-09-16
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
Angew.Chem.Int.Ed.Engl., 54, 2015
5AC0
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OVIS ARIES ALDEHYDE DEHYDROGENASE 1A1 IN COMPLEX WITH A DUOCARMYCIN ANALOG
Descriptor:RETINAL DEHYDROGENASE 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, ...
Authors:Koch, M.F., Harteis, S., Blank, I.D., Pestel, G., Tietze, L.F., Ochsenfeld, C., Schneider, S., Sieber, S.A.
Deposit date:2015-08-10
Release date:2015-08-26
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
Angew.Chem.Int.Ed.Engl., 54, 2015
5AC1
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SHEEP ALDEHYDE DEHYDROGENASE 1A1 WITH DUOCARMYCIN ANALOG INHIBITOR
Descriptor:RETINAL DEHYDROGENASE 1, 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, [[(2R,3S,4R,5R)-5-[(3R)-3-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanidyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphate, ...
Authors:Koch, M.F., Harteis, S., Blank, I.D., Pestel, G., Tietze, L.F., Ochsenfeld, C., Schneider, S., Sieber, S.A.
Deposit date:2015-08-11
Release date:2015-08-26
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
Angew.Chem.Int.Ed.Engl., 54, 2015
5AC2
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HUMAN ALDEHYDE DEHYDROGENASE 1A1 WITH DUOCARMYCIN ANALOG
Descriptor:RETINAL DEHYDROGENASE 1, 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, YTTERBIUM (III) ION, ...
Authors:Koch, M.F., Harteis, S., Blank, I.D., Pestel, G., Tietze, L.F., Ochsenfeld, C., Schneider, S., Sieber, S.A.
Deposit date:2015-08-11
Release date:2015-08-26
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
Angew.Chem.Int.Ed.Engl., 54, 2015
4G79
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STRUCTURE A C. ELEGANS SAS-6 VARIANT
Descriptor:Spindle assembly abnormal protein 6, GLYCEROL, TETRAETHYLENE GLYCOL
Authors:Erat, M.C., Vakonakis, I.
Deposit date:2012-07-20
Release date:2013-06-19
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GEU
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STRUCTURE OF A STABILISED CESAS-6 DIMER
Descriptor:Spindle assembly abnormal protein 6, GLYCEROL, TETRAETHYLENE GLYCOL
Authors:Erat, M.C., Vakonakis, I.
Deposit date:2012-08-02
Release date:2013-06-19
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GEX
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STRUCTURE OF A STABILISED CESAS-6 DIMER, SECOND CRYSTAL FORM
Descriptor:Spindle assembly abnormal protein 6, SULFATE ION
Authors:Erat, M.C., Vakonakis, I.
Deposit date:2012-08-02
Release date:2013-06-19
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GFA
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N-TERMINAL COILED-COIL DIMER OF C.ELEGANS SAS-6, CRYSTAL FORM A
Descriptor:Spindle assembly abnormal protein 6, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Erat, M.C., Vakonakis, I.
Deposit date:2012-08-03
Release date:2013-06-19
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GFC
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N-TERMINAL COILED-COIL DIMER OF C.ELEGANS SAS-6, CRYSTAL FORM B
Descriptor:Spindle assembly abnormal protein 6, 1,2-ETHANEDIOL, IMIDAZOLE, ...
Authors:Erat, M.C., Vakonakis, I.
Deposit date:2012-08-03
Release date:2013-06-19
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4TPZ
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N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P F145W (NN2)
Descriptor:Centriole protein
Authors:Hilbert, M., Kraatz, S.H.W.
Deposit date:2014-06-10
Release date:2015-06-24
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016