Author results

1TRL
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NMR SOLUTION STRUCTURE OF THE C-TERMINAL FRAGMENT 255-316 OF THERMOLYSIN: A DIMER FORMED BY SUBUNITS HAVING THE NATIVE STRUCTURE
Descriptor:THERMOLYSIN FRAGMENT 255 - 316
Authors:Rico, M., Jimenez, M.A., Gonzalez, C., De Filippis, V., Fontana, A.
Deposit date:1994-09-02
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of the C-terminal fragment 255-316 of thermolysin: a dimer formed by subunits having the native structure.
Biochemistry, 33, 1994
1TUC
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ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT S19-P20
Descriptor:ALPHA-SPECTRIN
Authors:Wilmanns, M., Serrano, L., Viguera, A.R.
Deposit date:1996-02-29
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
1TUD
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ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48
Descriptor:ALPHA-SPECTRIN
Authors:Viguera, A.R., Serrano, L., Wilmanns, M.
Deposit date:1996-02-29
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
1AEY
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ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, SOLUTION NMR, 15 STRUCTURES
Descriptor:ALPHA-SPECTRIN
Authors:Blanco, F.J., Ortiz, A.R., Serrano, L.
Deposit date:1997-03-02
Release date:1997-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: comparison of unrefined and refined structure sets with the crystal structure.
J.Biomol.NMR, 9, 1997
1PU1
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SOLUTION STRUCTURE OF THE HYPOTHETICAL PROTEIN MTH677 FROM METHANOTHERMOBACTER THERMAUTOTROPHICUS
Descriptor:Hypothetical protein MTH677
Authors:Blanco, F.J., Yee, A., Campos-Olivas, R., Devos, D., Valencia, A., Arrowsmith, C.H., Rico, M.
Deposit date:2003-06-23
Release date:2004-06-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the hypothetical protein Mth677 from Methanobacterium thermoautotrophicum: A novel {alpha}+{beta} fold
Protein Sci., 13, 2004
2JA4
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CRYSTAL STRUCTURE OF CD5 DOMAIN III REVEALS THE FOLD OF A GROUP B SCAVENGER CYSTEINE-RICH RECEPTOR
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD5
Authors:Rodamilans, B., Munoz, I.G., Sarrias, M.R., Lozano, F., Blanco, F.J., Montoya, G.
Deposit date:2006-11-21
Release date:2007-03-06
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal Structure of the Third Extracellular Domain of Cd5 Reveals the Fold of a Group B Scavenger Cysteine-Rich Receptor Domain.
J.Biol.Chem., 282, 2007
2O7M
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THE C-TERMINAL LOOP OF THE HOMING ENDONUCLEASE I-CREI IS ESSENTIAL FOR DNA BINDING AND CLEAVAGE. IDENTIFICATION OF A NOVEL SITE FOR SPECIFICITY ENGINEERING IN THE I-CREI SCAFFOLD
Descriptor:DNA endonuclease I-CreI
Authors:Prieto, J., Redondo, P., Padro, D., Blanco, F.J., Paques, F., Montoya, G.
Deposit date:2006-12-11
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage
Nucleic Acids Res., 35, 2007
2OTT
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CRYSTAL STRUCTURE OF CD5_DIII
Descriptor:T-cell surface glycoprotein CD5
Authors:Rodamilans, B.
Deposit date:2007-02-09
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain.
J.Biol.Chem., 282, 2007
2JTO
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SOLUTION STRUCTURE OF TICK CARBOXYPEPTIDASE INHIBITOR
Descriptor:Carboxypeptidase inhibitor
Authors:Pantoja-Uceda, D., Blanco, F.J.
Deposit date:2007-08-03
Release date:2008-07-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The NMR structure and dynamics of the two-domain tick carboxypeptidase inhibitor reveal flexibility in its free form and stiffness upon binding to human carboxypeptidase B.
Biochemistry, 47, 2008
2VBJ
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MOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS
Descriptor:DNA ENDONUCLEASE I-CREI, 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', ...
Authors:Redondo, P., Prieto, J., Munoz, I.G., Alibes, A., Stricher, F., Serrano, L., Arnould, S., Perez, C., Cabaniols, J.P., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G.
Deposit date:2007-09-14
Release date:2008-10-28
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
2VBL
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MOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS
Descriptor:DNA ENDONUCLEASE I-CREI, 5'-D(*DT*DC*DT*DG*DC*DC*DT*DT*DT*DT*DT*DT *DGP*DAP)-3', 5'-D(*DT*DT*DA*DG*DG*DA*DT*DC*DC*DT*DT*DC *DAP*DAP)-3', ...
Authors:Redondo, P., Prieto, J., Munoz, I.G., Alibes, A., Stricher, F., Serrano, L., Arnould, S., Perez, C., Cabaniols, J.P., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G.
Deposit date:2007-09-14
Release date:2008-10-28
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
2VBN
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MOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS
Descriptor:DNA ENDONUCLEASE I-CREI, 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP)-3', 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP)-3', ...
Authors:Redondo, P., Prieto, J., Munoz, I.G., Alibes, A., Stricher, F., Serrano, L., Arnould, S., Perez, C., Cabaniols, J.P., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G.
Deposit date:2007-09-14
Release date:2008-10-28
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
2VBO
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MOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS
Descriptor:DNA ENDONUCLEASE I-CREI, 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', ...
Authors:Redondo, P., Prieto, J., Munoz, I.G., Alibes, A., Stricher, F., Serrano, L., Arnould, S., Perez, C., Cabaniols, J.P., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G.
Deposit date:2007-09-14
Release date:2008-10-28
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
2VNF
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MOLECULAR BASIS OF HISTONE H3K4ME3 RECOGNITION BY ING4
Descriptor:INHIBITOR OF GROWTH PROTEIN 4, HISTONE H3, SODIUM ION, ...
Authors:Palacios, A., Munoz, I.G., Pantoja-Uceda, D., Marcaida, M.J., Torres, D., Martin-Garcia, J.M., Luque, I., Montoya, G., Blanco, F.J.
Deposit date:2008-02-04
Release date:2008-04-01
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Molecular Basis of Histone H3K4Me3 Recognition by Ing4
J.Biol.Chem., 283, 2008
2K1J
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PLAN HOMEODOMAIN FINGER OF TUMOUR SUPRESSOR ING4
Descriptor:Inhibitor of growth protein 4, ZINC ION
Authors:Palacios, A., Garcia, P., Padro, D., Lopez-Hernandez, E., Blanco, F.J.
Deposit date:2008-03-05
Release date:2008-04-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and NMR characterization of the binding to methylated histone tails of the plant homeodomain finger of the tumour suppressor ING4.
Febs Lett., 580, 2006
2K2X
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SOLUTION STRUCTURE OF TICK CARBOXYPEPTIDASE INHIBITOR AT PH 3.5
Descriptor:Carboxypeptidase inhibitor
Authors:Pantoja-Uceda, D., Blanco, F.
Deposit date:2008-04-15
Release date:2009-01-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2K2Y
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SOLUTION STRUCTURE OF THE FOLDED DOMAIN OF INTERMEDIATE IIIA OF TICK CARBOXYPEPTIDASE INHIBITOR
Descriptor:Carboxypeptidase inhibitor
Authors:Pantoja-Uceda, D., Blanco, F.
Deposit date:2008-04-15
Release date:2009-01-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2K2Z
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SOLUTION STRUCTURE OF THE FOLDED DOMAIN OF INTERMEDIATE IIIB OF TICK CARBOXYPEPTIDASE INHIBITOR
Descriptor:Carboxypeptidase inhibitor
Authors:Pantoja-Uceda, D., Blanco, F.
Deposit date:2008-04-15
Release date:2009-01-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2VS7
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH DNA AND CA
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP *GP*TP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP *CP*TP*TP*AP*CP*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', ...
Authors:Marcaida, M.J., Prieto, J., Redondo, P., Nadra, A.D., Alibes, A., Serrano, L., Grizot, S., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G.
Deposit date:2008-04-21
Release date:2008-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VS8
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH DNA AND MN
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP *GP*TP*AP*A)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*CP* DGP*DCP*DGP)-3', ...
Authors:Marcaida, M.J., Prieto, J., Redondo, P., Nadra, A.D., Alibes, A., Serrano, L., Grizot, S., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G.
Deposit date:2008-04-21
Release date:2008-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.
Proc.Natl.Acad.Sci.USA, 105, 2008
2KG4
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THREE-DIMENSIONAL STRUCTURE OF HUMAN GADD45ALPHA IN SOLUTION BY NMR
Descriptor:Growth arrest and DNA-damage-inducible protein GADD45 alpha
Authors:Sanchez, R., Pantoja-Uceda, D., Prieto, J., Diercks, T., Campos-Olivas, R., Blanco, F.J.
Deposit date:2009-03-04
Release date:2009-03-31
Last modified:2012-02-01
Method:SOLUTION NMR
Cite:Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase
J.Biol.Chem., 285, 2010
2KPZ
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HUMAN NEDD4 3RD WW DOMAIN COMPLEX WITH THE HUMAN T-CELL LEUKEMIA VIRUS 1 GAG-PRO POLIPROTEIN DERIVED PEPTIDE SDPQIPPPYVEP
Descriptor:E3 ubiquitin-protein ligase NEDD4, 12-mer from Gag-Pro polyprotein
Authors:Iglesias-Bexiga, M., Macias, M., Bonet, R., Blanco, F.J., Cobos, E.S., Luque, I.
Deposit date:2009-10-23
Release date:2010-11-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Human NEDD4 3RD WW Domain Complex with Human T-cell Leukemia virus GAP-Pro Poliprotein Derived Peptide
To be Published
2KQ0
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HUMAN NEDD4 3RD WW DOMAIN COMPLEX WITH EBOLA ZAIRE VIRUS MATRIX PROTEIN VP40 DERIVED PEPTIDE ILPTAPPEYMEA
Descriptor:E3 ubiquitin-protein ligase NEDD4, 12-mer from Matrix protein VP40
Authors:Iglesias-Bexiga, M., Macias, M., Bonet, R., Blanco, F.J., Cobos, E.S., Luque, I.
Deposit date:2009-10-23
Release date:2010-11-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Human NEDD4 3rd WW Domain Complex with Ebola Zaire Virus Matrix Protein VP40 Derived Peptide
To be Published
3MX9
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MOLECULAR BASIS OF ENGINEERED MEGANUCLEASE TARGETING OF THE ENDOGENOUS HUMAN RAG1 LOCUS
Descriptor:Protein scV3V2(G19S), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3'), ...
Authors:Munoz, I.G., Prieto, J., Subramanian, S., Coloma, J., Montoya, G.
Deposit date:2010-05-07
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
3MXA
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MOLECULAR BASIS OF ENGINEERED MEGANUCLEASE TARGETING OF THE ENDOGENOUS HUMAN RAG1 LOCUS
Descriptor:scV3V2(G19S), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(P*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ...
Authors:Munoz, I.G., Prieto, J., Subramanian, S., Coloma, J., Montoya, G.
Deposit date:2010-05-07
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
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