Author results

5UD9
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CRYSTAL STRUCTURE OF 354BG18 FAB
Descriptor:Fab heavy chain, Light chain
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2016-12-23
Release date:2017-02-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
6MEE
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BROADLY NEUTRALIZING ANTIBODIES AGAINST HCV USE A CDRH3 DISULFIDE MOTIF TO RECOGNIZE AN E2 GLYCOPROTEIN SITE THAT CAN BE TARGETED FOR VACCINE DESIGN
Descriptor:antibody HEPC74 Heavy Chain, antibody HEPC74 Light Chain
Authors:Flyak, A.I., Bjorkman, P.J.
Deposit date:2018-09-06
Release date:2018-11-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
6MEG
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BROADLY NEUTRALIZING ANTIBODIES AGAINST HCV USE A CDRH3 DISULFIDE MOTIF TO RECOGNIZE AN E2 GLYCOPROTEIN SITE THAT CAN BE TARGETED FOR VACCINE DESIGN
Descriptor:antibody HEPC46 Heavy Chain, antibody HEPC46 Light Chain
Authors:Flyak, A.I., Bjorkman, P.J.
Deposit date:2018-09-06
Release date:2018-11-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
5UEL
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CRYSTAL STRUCTURE OF 354NC102 FAB
Descriptor:354NC102 Fab Heavy Chain, 354NC102 Fab Light Chain, SULFATE ION
Authors:Sievers, S.A., Gristick, H.B., Bjorkman, P.J.
Deposit date:2017-01-02
Release date:2017-02-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
1L6X
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FC FRAGMENT OF RITUXIMAB BOUND TO A MINIMIZED VERSION OF THE B-DOMAIN FROM PROTEIN A CALLED Z34C
Descriptor:IMMUNOGLOBULIN GAMMA-1 HEAVY CHAIN CONSTANT REGION, Minimized B-domain of Protein A Z34C, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Idusogie, E.E., Presta, L.G., Santoro-Gazzano, H., Totpal, K., Wong, P.Y., Ultsch, M., Meng, Y.G., Mullkerrin, M.G.
Deposit date:2002-03-14
Release date:2002-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc.
J.Immunol., 164, 2000
4JDV
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CRYSTAL STRUCTURE OF GERM-LINE PRECURSOR OF NIH45-46 FAB
Descriptor:Fab heavy chain, Fab light chain, SULFATE ION, ...
Authors:Diskin, R., Scharf, L., Bjorkman, P.J.
Deposit date:2013-02-25
Release date:2013-03-20
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
1DQG
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CRYSTAL STRUCTURE OF THE CYSTEINE RICH DOMAIN OF MANNOSE RECEPTOR
Descriptor:MANNOSE RECEPTOR, SULFATE ION
Authors:Liu, Y., Chirino, A.J., Misulovin, Z., Leteux, C., Feizi, T., Nussenzweig, M.C., Bjorkman, P.J.
Deposit date:2000-01-04
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the cysteine-rich domain of mannose receptor complexed with a sulfated carbohydrate ligand.
J.Exp.Med., 191, 2000
5F1S
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CRYSTAL STRUCTURE OF THE TELEOST FISH POLYMERIC IG RECEPTOR (PIGR) ECTODOMAIN
Descriptor:polymeric Immunoglobulin Receptor
Authors:Stadtmueller, B.M., Bjorkman, P.J.
Deposit date:2015-11-30
Release date:2016-03-16
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins.
Elife, 5, 2016
3S3Z
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CRYSTAL STRUCTURE AN TANDEM CYANOVIRIN-N DIMER, CVN2L10
Descriptor:Tandem Cyanovirin-N Dimer CVN2L10, SODIUM ION
Authors:Keeffe, J.R., Bjorkman, P.J., Mayo, S.L.
Deposit date:2011-05-18
Release date:2011-08-03
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Designed oligomers of cyanovirin-N show enhanced HIV neutralization.
Proc.Natl.Acad.Sci.USA, 108, 2011
2GIY
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE HSV-1 GE ECTODOMAIN
Descriptor:Glycoprotein E
Authors:Sprague, E.R., Wang, C., Baker, D., Bjorkman, P.J.
Deposit date:2006-03-29
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging.
Plos Biol., 4, 2006
2GW5
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CRYSTAL STRUCTURE OF LIR-2 (ILT4) AT 1.8 : DIFFERENCES FROM LIR-1 (ILT2) IN REGIONS IMPLICATED IN THE BINDING OF THE CYTOMEGALOVIRUS CLASS I MHC HOMOLOG UL18
Descriptor:Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor, ISOPROPYL ALCOHOL
Authors:Willcox, B.E., Thomas, L.M., Chapman, T.L., Heikema, A.P., West, A.P., Bjorkman, P.J.
Deposit date:2006-05-03
Release date:2006-06-20
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of LIR-2 (ILT4) at 1.8 A: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18.
Bmc Struct.Biol., 2, 2002
3P4L
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CRYSTAL STRUCTURE OF A HEMOJUVELIN-BINDING FRAGMENT OF NEOGENIN
Descriptor:Neogenin
Authors:Yang, F., West Jr., A.P., Bjorkman, P.J.
Deposit date:2010-10-06
Release date:2010-11-17
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a hemojuvelin-binding fragment of neogenin at 1.8A.
J.Struct.Biol., 174, 2011
4YDL
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY C38-VRC18.02 IN COMPLEX WITH HIV-1 CLADE AE STRAIN 93TH057GP120
Descriptor:Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY C38-VRC18.02, LIGHT CHAIN OF ANTIBODY C38-VRC18.02, ...
Authors:Zhou, T., Srivatsan, S., Kwong, P.D.
Deposit date:2015-02-22
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
2VSD
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CRYSTAL STRUCTURE OF CHIR-AB1
Descriptor:CHIR AB1, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Arnon, T.I., Kaiser, J.T., Bjorkman, P.J.
Deposit date:2008-04-22
Release date:2008-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The Crystal Structure of Chir-Ab1: A Primordial Avian Classical Fc Receptor.
J.Mol.Biol., 381, 2008
1FWU
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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR COMPLEXED WITH 3-SO4-LEWIS(X)
Descriptor:CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR, O3-SULFONYLGALACTOSE, BETA-METHYL-N-ACETYL-D-GLUCOSAMINE, ...
Authors:Liu, Y., Misulovin, Z., Bjorkman, P.J.
Deposit date:2000-09-24
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The molecular mechanism of sulfated carbohydrate recognition by the cysteine-rich domain of mannose receptor.
J.Mol.Biol., 305, 2001
1HSB
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DIFFERENT LENGTH PEPTIDES BIND TO HLA-AW68 SIMILARLY AT THEIR ENDS BUT BULGE OUT IN THE MIDDLE
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-AW68.1), BETA 2-MICROGLOBULIN, BOUND PEPTIDE FRAGMENT, ...
Authors:Guo, H.-C., Strominger, J.L., Wiley, D.C.
Deposit date:1993-03-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle.
Nature, 360, 1992
1XED
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CRYSTAL STRUCTURE OF A LIGAND-BINDING DOMAIN OF THE HUMAN POLYMERIC IG RECEPTOR, PIGR
Descriptor:Polymeric-immunoglobulin receptor, MAGNESIUM ION
Authors:Hamburger, A.E., West Jr., A.P., Bjorkman, P.J.
Deposit date:2004-09-10
Release date:2004-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of a Polymeric Immunoglobulin Binding Fragment of the Human Polymeric Immunoglobulin Receptor
Structure, 12, 2004
4FQ2
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CRYSTAL STRUCTURE OF 10-1074 FAB
Descriptor:Fab heavy chain, Fab light chain, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, ...
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2012-06-24
Release date:2012-11-14
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
5F7E
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CRYSTAL STRUCTURE OF GERM-LINE PRECURSOR OF 3BNC60 FAB
Descriptor:Fab heavy chain, Fab light chain
Authors:Sievers, S.A., Scharf, L., Jiang, S., Bjorkman, P.J.
Deposit date:2015-12-08
Release date:2016-04-06
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
1Z6O
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CRYSTAL STRUCTURE OF TRICHOPLUSIA NI SECRETED FERRITIN
Descriptor:Ferritin light chain, Ferritin heavy chain, FE (III) ION, ...
Authors:Hamburger, A.E., West Jr., A.P., Hamburger, Z.A., Hamburger, P., Bjorkman, P.J.
Deposit date:2005-03-22
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains.
J.Mol.Biol., 349, 2005
1T7V
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ZN-ALPHA-2-GLYCOPROTEIN; BACULO-ZAG PEG 200
Descriptor:Zinc-alpha-2-glycoprotein, N-ACETYL-D-GLUCOSAMINE, HEXAETHYLENE GLYCOL
Authors:Delker, S.L., West Jr., A.P., McDermott, L., Kennedy, M.W., Bjorkman, P.J.
Deposit date:2004-05-11
Release date:2004-12-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein.
J.Struct.Biol., 148, 2004
6MEH
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BROADLY NEUTRALIZING ANTIBODIES AGAINST HCV USE A CDRH3 DISULFIDE MOTIF TO RECOGNIZE AN E2 GLYCOPROTEIN SITE THAT CAN BE TARGETED FOR VACCINE DESIGN
Descriptor:E2 glycoprotein, antibody HEPC74 Heavy Chain, antibody HEPC74 Light Chain, ...
Authors:Flyak, A.I., Bjorkman, P.J.
Deposit date:2018-09-06
Release date:2018-11-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
1CFB
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CRYSTAL STRUCTURE OF TANDEM TYPE III FIBRONECTIN DOMAINS FROM DROSOPHILA NEUROGLIAN AT 2.0 ANGSTROMS
Descriptor:DROSOPHILA NEUROGLIAN, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ...
Authors:Huber, A.H., Wang, Y.E., Bieber, A.J., Bjorkman, P.J.
Deposit date:1994-08-27
Release date:1994-11-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of tandem type III fibronectin domains from Drosophila neuroglian at 2.0 A.
Neuron, 12, 1994
2CLR
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THREE DIMENSIONAL STRUCTURE OF A PEPTIDE EXTENDING OUT ONE END OF A CLASS I MHC BINDING SITE
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, DECAMERIC PEPTIDE FROM CALRETICULIN
Authors:Collins, E.J., Garboczi, D.N., Wiley, D.C.
Deposit date:1994-08-01
Release date:1995-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of a peptide extending from one end of a class I MHC binding site.
Nature, 371, 1994
3S3Y
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CRYSTAL STRUCTURE AN TANDEM CYANOVIRIN-N DIMER, CVN2L0
Descriptor:TANDEM CYANOVIRIN-N DIMER CVN2L0, SODIUM ION
Authors:Keeffe, J.R., Bjorkman, P.J., Mayo, S.L.
Deposit date:2011-05-18
Release date:2011-08-03
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Designed oligomers of cyanovirin-N show enhanced HIV neutralization.
Proc.Natl.Acad.Sci.USA, 108, 2011